A5041895823- Cancer-related molecular mechanisms research
- Genetic and Kidney Cyst Diseases
- Hippo pathway signaling and YAP/TAZ
- S100 Proteins and Annexins
- Liver Disease Diagnosis and Treatment
- Microtubule and mitosis dynamics
- RNA Research and Splicing
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Bone Metabolism and Diseases
- Liver physiology and pathology
- RNA modifications and cancer
- Hepatocellular Carcinoma Treatment and Prognosis
- Ubiquitin and proteasome pathways
- Protist diversity and phylogeny
- Heat shock proteins research
- Hepatitis B Virus Studies
- Drug-Induced Hepatotoxicity and Protection
- Cellular Mechanics and Interactions
Shaoxing University
2020-2023
Zhejiang University
2023
Nanjing Drum Tower Hospital
2019
Nanjing Medical University
2017-2018
Jiangsu Province Hospital
2017-2018
In this study, we characterized the expression of 32 other kinesin superfamily proteins (KIFs) and analyzed their association with progression prognosis hepatocellular carcinoma (HCC).The data from 295 HCC patients The Cancer Genome Atlas were included in study. An independent t-test was used to compare KIF levels adjacent tissues. Pearson's Chi-square test assess relationships tumor biomarkers clinicopathological parameters. Kaplan-Meier plots log-rank tests analyze survival, univariate...
Long non-coding RNAs (lncRNAs) play essential roles in diverse biological processes; however, current understanding of the mechanism underlying regulation tumour proliferation and metastasis is limited. Lung cancer-associated transcript 1 (LUCAT1) has been reported a variety human cancers, while its role hepatocellular carcinoma (HCC) remains unclear. This study aimed to determine LUCAT1 on progression HCC cells clinical specimens. Our results demonstrated that was up-regulated tissues...
Abstract Hepatocellular carcinoma (HCC) is the most prevalent subtype of liver cancer, and it characterized by high rate metastasis recurrence. Recent studies have boosted our understanding that Gankyrin contributes to both these pathological properties, but mechanisms underlying its aberrant regulation are poorly understood. Recently, many long noncoding RNAs (lncRNAs) been reported be involved in regulating expression oncogenes anti-oncogenes through various mechanisms. Here, using...
We evaluated microwave-assisted liver resection for hepatocellular carcinoma.We enrolled 79 patients in this study, and microwave ablation was used resection. Patients were randomized to group A (50.6%; n = 40), without ablation, or B (49.4%; 39), performed using ablation. Data analyzed statistical significance.Of the participants enrolled, 60 male, participant's average age 59.32 ± 10.34 years. The mean overall tumor diameter 4.39 (2.00) cm, did not differ between groups. Intraoperative...
Objective To investigate the effects and mechanisms of receptor-interacting serine-threonine kinase 3 (RIP3) in formation cholestatic hepatic injury. Methods The experimental study was conducted. (1) Processing viability stellate cell line HSC-T6: HSC-T6 cells were transfected by RIP3-siRNA NC-siRNA, respectively. The viabilities un-transfected, RIP3-siRNA-transfected NC-siRNA-transfected respectively measured cell-counting kit-8 (CCK-8). treated 100 μmol/L Glycochenodeoxycholic acid...
Objective: To investigate the effect and mechanism of psoralen on calvarial osteoblasts injuries caused by tricalcium phosphate (TCP) wear particles in vitro.Methods: Primary were obtained from calvaria neonatal SD rat series digestion identified with ALP staining. Calvarial treated TCP for 48 h to establish vitro model injuries. The randomly divided into control group, (0.1 mg/ml) (at concentrations 10-7, 10-6, 10-5 mol/L) groups. WST assay flow cytometry used detect cell viability...