A5036508761- Viral Infections and Vectors
- Air Quality and Health Impacts
- Mosquito-borne diseases and control
- Toxic Organic Pollutants Impact
- Extracellular vesicles in disease
- Radiation Therapy and Dosimetry
- Drug Transport and Resistance Mechanisms
- Neuroendocrine Tumor Research Advances
- Systemic Lupus Erythematosus Research
- Cancer, Lipids, and Metabolism
- DNA Repair Mechanisms
- Genomics, phytochemicals, and oxidative stress
- Malaria Research and Control
- Autoimmune and Inflammatory Disorders Research
- Epigenetics and DNA Methylation
Universidade Federal do Paraná
2021-2023
Universidade de Cuiabá
2020-2023
Introduction: Chikungunya chronic joint disease causes debilitating arthralgia, significantly impacting the quality of life affected individuals. Methods: In this study, patients underwent clinical follow-ups, biopsies, and pre-biopsy 24 months post-biopsy serum dosage cytokines. Results: All participants were female had pain in 12 joints on average, with 41.17% exhibiting moderate activity. Histopathological analysis revealed collagen deposition. Indirect immunofluorescence detected CHIKV...
Persistent organic pollutants (POPs) may alter tumor cells phenotype, possibly increasing malignancy, but there is a lack of studies investigating the mechanisms by which POPs affect cells. The ATP-Binding Cassette (ABC) transporter proteins are widely studied component drug resistance and progression. We hypothesized that levels BDE-209 TCDD detected in human serum can modulate gene expression or activity ATP-binding cassette transporters murine melanoma (B16-F1) In this study, we observed...
Chikungunya virus (CHIKV) is a global emergent arthritogenic alphavirus transmitted by anthropophilic Stegomyia mosquitoes. fever may evolve to chronic arthralgia in 57-80% of infected patients. This study was developed identify possibly fast, simple low-cost biomarkers monitor CHIKV-induced articular disease. Between 2017 and 2018, we analyzed clinical data patients meeting the criteria established standard protocols define chikungunya Patients were classified according disease activity...