Renata Dezengrini Slhessarenko

ORCID: 0000-0002-3246-899X
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About
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Research Areas
  • Mosquito-borne diseases and control
  • Viral Infections and Vectors
  • Insect symbiosis and bacterial influences
  • Malaria Research and Control
  • SARS-CoV-2 and COVID-19 Research
  • Parvovirus B19 Infection Studies
  • Vector-Borne Animal Diseases
  • Vector-borne infectious diseases
  • Viral Infections and Outbreaks Research
  • Animal Virus Infections Studies
  • COVID-19 Clinical Research Studies
  • Medicinal Plants and Bioactive Compounds
  • Vitamin C and Antioxidants Research
  • Viral gastroenteritis research and epidemiology
  • Inflammasome and immune disorders
  • Yersinia bacterium, plague, ectoparasites research
  • Lipoproteins and Cardiovascular Health
  • Virology and Viral Diseases
  • Coronary Interventions and Diagnostics
  • COVID-19 Impact on Reproduction
  • Cytomegalovirus and herpesvirus research
  • Environmental and biological studies
  • Autoimmune and Inflammatory Disorders Research
  • COVID-19 epidemiological studies
  • Respiratory viral infections research

Universidade Federal de Mato Grosso
2016-2025

This study aimed to verify the diversity of Culicidae species and their frequency infection with flaviviruses alphaviruses in Cuiabá, state Mato Grosso, Brazil. Mosquitoes were captured Nasci aspirators hand net 200 census tracts, identified alive at level pooled one-20 (11,090 mosquitoes, 14 species). Female pools (n = 610) subjected multiplex seminested-reverse transcription-polymerase chain reaction (RT-PCR) for 11 flavivirus five alphavirus. Positive tested by single RT-PCR followed...

10.1590/0074-02760150270 article EN cc-by Memórias do Instituto Oswaldo Cruz 2016-01-01

This study aimed to investigate the circulation of Orthobunyavirus species in state Mato Grosso (MT) Brazil. During a dengue outbreak 2011/2012, 529 serum samples were collected from patients with acute febrile illness symptoms for up five days and 387 pools female Culex quinquefasciatus captured 2013 subjected nested-reverse transcription-polymerase chain reaction segment S Simbu serogroup followed by nucleotide sequencing virus isolation Vero cells. Patients (5/529; 0.9%) Cuiabá (n = 3),...

10.1590/0074-02760150123 article EN cc-by Memórias do Instituto Oswaldo Cruz 2015-09-01

Mayaro virus (MAYV) is frequently reported in Pan-Amazonia. The aim of this study was to investigate the circulation alphaviruses during a dengue outbreak state Mato Grosso, Brazil. Serum samples from dengue-suspected patients were subjected multiplex semi-nested reverse transcriptase polymerase chain reaction for 11 flaviviruses and five alphaviruses, nucleotide sequencing viral isolation. MAYV detected 15 (2.5%) 604 patients. Twelve co-infected with 4, which isolated 10 molecular detection...

10.1590/0074-0276140108 article EN cc-by Memórias do Instituto Oswaldo Cruz 2014-08-16

Mayaro virus (MAYV) is an arbovirus that circulates in Latin America and emerging as a potential threat to public health. Infected individuals develop fever, severe inflammatory disease characterized by high rash, arthralgia, myalgia headache. The often associated with prolonged arthralgia mediated chronic inflammation can last months. Although the immune response against other arboviruses, such chikungunya (CHIKV), dengue (DENV) Zika (ZIKV), has been extensively studied, little known about...

10.1371/journal.ppat.1007934 article EN cc-by PLoS Pathogens 2019-09-03

Abstract Vertical transmission to progeny ensures the maintenance of arboviruses in their natural vectors. This mechanism is largely reported for dengue virus (DENV) and yellow fever (YFV). Few studies have addressed this Zika (ZIKV), Mayaro (MAYV) other arboviruses. The present study investigated infection rate by 4490 Aedes ( Stegomyia ) aegypti 296 albopictus (Diptera: Culicidae reared from eggs collected with ovitraps Cuiabá, Mato Grosso State, February July, 2017. After viral RNA...

10.1111/mve.12369 article EN Medical and Veterinary Entomology 2019-02-18

Dengue is the most prevalent arboviral disease in tropical areas. In Mato Grosso, outbreaks are reported every year, but studies on dengue this state scarce.Natural transovarial infection of Aedes aegypti by a flavivirus was investigated Jardim Industriário neighborhood Cuiabá, Grosso. Eggs were collected with ovitraps during dry, intermediate, and rainy seasons 2012. After eggs hatched larvae developed to adulthood, mosquitoes (n = 758) identified allocated pools 1-10 specimens according...

10.1590/0037-8682-0264-2014 article EN cc-by Revista da Sociedade Brasileira de Medicina Tropical 2015-02-01

Mayaro virus (MAYV) is a neglected arthropod-borne (arbovirus) antigenically clustered into the Semliki Forest complex group of Alphavirus genus ( Togaviridae family), maintained in an unclear zoonotic cycle involving mosquitoes from Haemagogus as main vector. The genome composed positive single-stranded RNA 11.5 kb length, which contains two genes that encode four nonstructural (nsP1 to nsP4) and five structural (C, E3, E2, 6K, E1) proteins.

10.1128/jcm.01892-18 article EN Journal of Clinical Microbiology 2019-02-21

Viruses are ubiquitous and diverse microorganisms arising as a result of interactions within their vertebrate invertebrate hosts. Here we report the presence different viruses in salivary glands 1657 mosquitoes classified over 28 culicinae species from North region Brazilian Pantanal wetland through metagenomics, viral isolation, RT-PCR. In total, 12 were found, eight putative novel with relatively low similarity pre-existing families, named Pirizal iflavirus, Furrundu phlebovirus, Pixé...

10.3390/v11100957 article EN cc-by Viruses 2019-10-17

DENV-2 was the main responsible for a 70% increase in dengue incidence Brazil during 2019. That year, our metagenomic study by Illumina NextSeq on serum samples from acute febrile patients (n = 92) with suspected arbovirus infection, sampled 22 cities of state Mato Grosso (MT), middle west Brazil, revealed eight complete genomes and two near-complete sequences genotype III, one Human parvovirus B19 I (5,391 nt) Coxsackievirus A6 lineage D (4,514 nt). These share aminoacidic identities BR4 E...

10.1016/j.meegid.2023.105487 article EN cc-by-nc-nd Infection Genetics and Evolution 2023-08-06

Abstract New species of insect‐specific viruses (ISV) have been reported worldwide. In the present study, complete genome Culex flavivirus (CxFV) and partial sequences other ISVs in quinquefasciatus Say 1823 females (n = 3425) sampled 200 urban areas census tracts Cuiaba, state Mato Grosso, were identified via reverse transcriptase‐polymerase chain reaction for a NS5 region flaviviruses, nucleotide high‐throughput sequencing, viral isolation C6/36 cells. CxFV was detected 16 403 mosquito...

10.1111/mve.12374 article EN Medical and Veterinary Entomology 2019-03-19

In the present study we evaluated features of different recombinant forms Zika virus (ZIKV) proteins produced in either bacterial (Eschericha coli) or insect cells (Drosophila melanogaster). The ZIKV-envelope glycoprotein (EZIKV) is responsible for entry into host cells, main target neutralizing antibodies and has been used as a antigen serological tests development subunit vaccines. EZIKV composed three structural functional domains (EDI, EDII, EDIII), which share extensive sequence...

10.3389/fimmu.2023.1071041 article EN cc-by Frontiers in Immunology 2023-03-16

Introduction: Chikungunya chronic joint disease causes debilitating arthralgia, significantly impacting the quality of life affected individuals. Methods: In this study, patients underwent clinical follow-ups, biopsies, and pre-biopsy 24 months post-biopsy serum dosage cytokines. Results: All participants were female had pain in 12 joints on average, with 41.17% exhibiting moderate activity. Histopathological analysis revealed collagen deposition. Indirect immunofluorescence detected CHIKV...

10.1590/0037-8682-0278-2023 article EN cc-by Revista da Sociedade Brasileira de Medicina Tropical 2023-01-01

INTRODUCTION The epidemiology of Rickettsia and Ehrlichia species infection is underestimated in Mato Grosso State. METHODS: Serum samples obtained during a Dengue outbreak 2011-2012 were tested via indirect immunofluorescence and/or ELISA. RESULTS: Samples from 19/506 (3.8%) patients presented antibodies for at least one three species; 2/506 (0.4%) reacted against canis. Most afflicted are residents cities the south-central region state, where these diseases have been reported animals....

10.1590/0037-8682-0318-2016 article EN cc-by Revista da Sociedade Brasileira de Medicina Tropical 2017-06-01

INTRODUCTION: Aedes aegypti and Culex quinquefasciatus are vector species responsible for the transmission of important arboviruses. METHODS: Adult mosquitoes were collected in urban areas four municipalities Mato Grosso within 1 year. RESULTS: A total 19,110 collected. Among them, 16,578 (86,8%) C. (44% female 56% male); 2,483 (13%), A. (Stegomyia) (54% 46% 49 (0,30%), from genus Psorophora, Anopheles, Coquilettidia, Sabethes. significant correlation was observed between number all dew...

10.1590/0037-8682-0185-2019 article EN cc-by Revista da Sociedade Brasileira de Medicina Tropical 2020-01-01
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