A5054690382- Psychosomatic Disorders and Their Treatments
- Functional Brain Connectivity Studies
- Neurological disorders and treatments
- Mental Health and Psychiatry
- Genetic Neurodegenerative Diseases
- Health Systems, Economic Evaluations, Quality of Life
- Neural and Behavioral Psychology Studies
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Healthcare Policy and Management
- Neurology and Historical Studies
- Clinical Reasoning and Diagnostic Skills
- Mental Health Research Topics
- Dementia and Cognitive Impairment Research
- Pharmaceutical Economics and Policy
- Advanced MRI Techniques and Applications
- Neurological and metabolic disorders
- Health, Environment, Cognitive Aging
- Advanced Neuroimaging Techniques and Applications
- Primary Care and Health Outcomes
- Patient Safety and Medication Errors
- Patient-Provider Communication in Healthcare
University Medical Center Groningen
2020-2025
University of Groningen
2021-2025
Currently, the pathophysiology of myoclonus-dystonia (M-D) remains insufficiently understood. This study addresses this gap by adding innovative multivariate pattern analysis (MVPA) to traditional univariate functional magnetic resonance imaging (fMRI) data. Data from 18 M-D patients and age-matched healthy volunteers who performed a finger tapping fMRI task were analyzed. Whole-brain searchlight with varying hemodynamic response function (HRF) delays employed examine brain responses...
Background: Given their crucial role in vaccine assessment, National Immunization Technical Advisory Groups (NITAGs) should be considered the Regulation on Health Technology Assessment (EU HTAR) to maximize benefits of EU HTAR for vaccines. This review and perspective piece identifies gaps arising from NITAGs potential lack involvement proposes strategies involving them. Methods: A targeted literature guideline was conducted evaluate NITAGs’ current future relation HTAR. The impact diverse...
Patients suffering from functional neurological disorder (FND) experience disabling symptoms not caused by an underlying classical disease (such as stroke or multiple sclerosis). The diagnosis is made based on reliable positive clinical signs, but clinicians often require additional time- and cost consuming medical tests examinations. Resting-state connectivity (RS FC) showed its potential imaging-based adjunctive biomarker to help distinguish patients healthy controls could represent a...
This exploratory study set out to investigate dynamic functional connectivity (dFC) in patients with jerky and tremulous movement disorders (JT-FMD). The focus this work is on brain states, which represent distinct dFC patterns that reoccur time across subjects. Resting-state fMRI data were collected from 17 JT-FMD healthy controls (HC). Symptom severity was measured using the Clinical Global Impression-Severity scale. Depression anxiety Beck Inventory (BDI) Anxiety (BAI), respectively....
Progression of amnestic mild cognitive impairment (aMCI) to Alzheimer's disease (AD) is a clinical event with highly variable progression rates varying from 10-15% up 30-34%. Functional connectivity (FC), the temporal similarity between spatially remote neurophysiological events, has previously been reported differ aMCI patients who progress AD (pMCI) and those do not (i.e., remain stable; sMCI). However, these reports had short-term follow-up provide insight into long-term...
Objective: To explore changes in resting-state networks patients with jerky and tremulous functional movement disorders (JT-FMD). Methods: Resting-state magnetic resonance imaging data from seventeen JT-FMD age-, sex-, education-matched healthy controls (HC) were investigated. Independent component analysis was used to examine the central executive network (CEN), salience network, default mode (DMN). Frequency distribution of signal fluctuations intra- internetwork connectivity Symptom...