A5054572577- Behavioral Health and Interventions
- Decision-Making and Behavioral Economics
- Effects of Radiation Exposure
- Smoking Behavior and Cessation
- Schizophrenia research and treatment
- Dementia and Cognitive Impairment Research
- Health Systems, Economic Evaluations, Quality of Life
- Radiation Therapy and Dosimetry
- Health disparities and outcomes
- Neural and Behavioral Psychology Studies
- Spaceflight effects on biology
- Carcinogens and Genotoxicity Assessment
- Psychological and Temporal Perspectives Research
- Optimal Experimental Design Methods
- Statistical Methods in Clinical Trials
- Radiation Dose and Imaging
- Neurological disorders and treatments
- Child and Adolescent Psychosocial and Emotional Development
- Parkinson's Disease Mechanisms and Treatments
- Radioactive contamination and transfer
- Diet and metabolism studies
- Neurotransmitter Receptor Influence on Behavior
- Balance, Gait, and Falls Prevention
- Multiple Myeloma Research and Treatments
- Meta-analysis and systematic reviews
University of Arkansas for Medical Sciences
2015-2024
Arkansas Children's Hospital
2020-2024
Radiation Effects Research Foundation
2015-2021
Johns Hopkins University
2012-2020
Clinical Research Institute
2020
Massachusetts General Hospital
2020
Johns Hopkins All Children's Hospital
2020
Arkansas Biosciences Institute
2020
Central Arkansas Veterans Healthcare System
2001-2014
City College of New York
2014
Tobacco use disproportionately affects lower socioeconomic status (SES) groups. Current explanations as to why SES groups respond less robustly tobacco control efforts and dependence treatment do not fully account for this disparity. The identification of factors that predict relapse in population might help clarify these differences. Good candidates novel prognostic include the constellation behaviors associated with executive function including self‐control/impulsiveness, propensity delay...
Glucocorticoids depress bone formation by inhibiting osteoblastogenesis and increasing osteoblast apoptosis. However, the role of resorption in initial rapid phase loss characteristic glucocorticoid-induced osteoporosis is unexplained, reason for efficacy bisphosphonates this condition remains unknown. We report that murine osteoclast cultures, glucocorticoids prolonged baseline survival osteoclasts antagonized bisphosphonate-induced caspase activation apoptosis a glucocorticoid...
Glucocorticoids depress bone formation by inhibiting osteoblastogenesis and increasing osteoblast apoptosis. However, the role of resorption in initial rapid phase loss characteristic glucocorticoid-induced osteoporosis is unexplained, reason for efficacy bisphosphonates this condition remains unknown. We report that murine osteoclast cultures, glucocorticoids prolonged baseline survival osteoclasts antagonized bisphosphonate-induced caspase activation apoptosis a glucocorticoid...
The purpose of the current study was to identify predictors delay discounting among adolescents receiving treatment for marijuana abuse or dependence, and test as a predictor outcome. Participants this were 165 (88% male) between ages 12 18 (mean age = 15.8 years; standard deviation 1.3 years) who enrolled in clinical trial comparing three behavioral treatments adolescent dependence. completed task at onset $100 $1,000 hypothetical money marijuana. Overall, smaller magnitude rewards...
To examine the benefit of adding an Internet-delivered behavior therapy to a buprenorphine medication program and voucher-based motivational incentives.
Several studies examining both control and substance-dependent populations have found delay discounting to remain stable over time. In this report, we examine whether changes in opioid-dependent individuals who complete a 12-week treatment. The 159 subjects completed assessments at baseline treatment-end come from two separate clinical trials: 56 Chopra et al. (2009) 103 Christensen (2012). Mean 12 weeks significantly decreased less than half (44.8%) of the level (95% CIs (27.5, 73.2))....
Although for more than a decade healthcare systems have attempted to provide evidence-based mental health treatments, the availability and use of psychotherapies remains low. A significant need exists identify simple but effective implementation strategies adopt complex practices within care. Emerging evidence suggests that facilitation may be an integrative strategy adoption practices. The current pilot examined external cognitive behavioral therapy (CBT) in 20 Department Veteran Affairs...
Given the lack of consensus regarding changes in temporal and probability discounting as a function smoking abstinence cigarette smokers, present study comprehensively examined possible these processes following period acute consistent with elevated withdrawal symptoms craving.Computerized assessments were collected from smokers normal 24-hr abstinence, order sessions counterbalanced across participants. Other conditions included commodity (money cigarettes), sign (gains losses), magnitude...
We examined socioeconomic disparities in a community-based tobacco dependence treatment program.We provided cognitive-behavioral and nicotine patches to 2739 smokers. use, clinical environmental, outcome differences by status (SES). used logistic regressions model end-of-treatment 3- 6-month outcomes.The probability of abstinence 3 months after was 55% greater for the highest-SES than lowest-SES (adjusted odds ratio [AOR] = 1.55; 95% confidence interval [CI] 1.03, 2.33) smokers increased 2.5...
Methionine, a central molecule in one-carbon metabolism, is an essential amino acid required for normal growth and development. Despite its importance to biological systems, methionine toxic when administered at supra-physiological levels. The aim of this study was investigate the effects short-term dietary modulation on proximal jejunum, section gut specifically responsible absorption, mouse model. Eight-week-old CBA/J male mice were fed methionine-adequate (MAD; 6.5 g/kg) or...
Delay discounting rates are predictive of drug use status, the likelihood becoming abstinent, and a variety health behaviors. Rates delay may also be related to other relevant behaviors associated with addiction, such as frequency at which individuals redeem contingency management voucher earnings. This study examined 152 participants in buprenorphine treatment program for opioid abuse. Participants received up 12 weeks combined management. Participant's was measured via urine specimens...
Nineteen nicotine-deprived cigarette smokers received monetary rewards for each minute they chose not to initiate smoking in 2-h laboratory sessions followed by a 30-min period of enforced abstinence from smoking. Reinforcer amounts were delivered according one three schedules: increasing, decreasing, and constant. Relapse time (time until first cigarette) was shortest the decreasing condition, longest increasing intermediate constant condition. All differences significant except...
Endogenous shikimic acid determinations are routinely used to assess the efficacy of glyphosate in plants. Numerous analytical methods exist public domain for detection acid, yet most commonly cited comprise spectrophotometric and high-pressure liquid chromatography (HPLC) methods. This paper compares an HPLC two (Spec 1 Spec 2) assesses effectiveness tissues glyphosate-treated Furthermore, study evaluates versatility acid-based extraction longevity plant extract samples under different...
Construal Level Theory states that psychologically proximal outcomes are construed concretely while distal abstractly. Previous research suggests the principles of can be applied to enhance self-control, as measured by delay discounting. The present studies replicate and expand on this work examining whether theory-informed priming manipulations lead discounting reductions in a repeated-measures design. Study 1 conceptually replicated previous work, with reduced observed function thinking...