A5039820818- Diabetes Management and Research
- Mental Health Treatment and Access
- Diabetes and associated disorders
- Global Public Health Policies and Epidemiology
- Vaccine Coverage and Hesitancy
- Child and Adolescent Psychosocial and Emotional Development
- SARS-CoV-2 and COVID-19 Research
- Pancreatic function and diabetes
- HIV/AIDS Research and Interventions
- Chronic Disease Management Strategies
- Diabetes Management and Education
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Global Health and Epidemiology
- Family Caregiving in Mental Illness
- Maternal Mental Health During Pregnancy and Postpartum
- HIV/AIDS Impact and Responses
- COVID-19 epidemiological studies
- Infant Development and Preterm Care
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Global Health and Surgery
- Cytomegalovirus and herpesvirus research
- COVID-19 diagnosis using AI
- Health disparities and outcomes
- COVID-19 Pandemic Impacts
- Digital Mental Health Interventions
Partners In Health
2022-2024
Sheba Medical Center
2024
Brigham and Women's Hospital
2022-2023
Public Health Institute of Malawi
2021-2023
Harvard University
2022
Problem Management Plus (PM+) is a low-intensity psychological intervention developed by the World Health Organization that can be delivered nonspecialists to address common mental health conditions in people affected adversity. Emerging evidence demonstrates efficacy of PM+ across range settings. However, published literature rarely documents adaptation processes for interventions context or culture, including curriculum implementation adaptations. Practical guidance adapting while...
Introduction: Chronic obstructive pulmonary disease (COPD) continues to pose a global public health challenge. However, literature is scarce on the burden of COPD in Malawi. We assessed prevalence and risk factors for among adults Neno, Methodology: conducted population-based analytical cross-sectional study Neno District between December 2021 November 2022. Using multi-stage sampling technique, we included 525 aged≥ 40 years. All participants underwent spirometry according American Thoracic...
Objectives The purpose of this qualitative study is to describe the acceptability and appropriateness continuous glucose monitoring (CGM) in people living with type 1 diabetes (PLWT1D) at first-level (district) hospitals Malawi. Design We conducted semistructured interviews among PLWT1D healthcare providers participating study. Standardised interview guides elicited perspectives on CGM use for their providers, provider effectiveness Data were coded using Dedoose software analysed a thematic...
Current low COVID-19 vaccination rates in low- and middle-income countries reflect an inequitable global vaccine distribution; however, local attitudes towards the are important factor to meet benchmarks. We describe toward uptake of perceptions among patients with NCDs their caregivers using cross-sectional data collected through telephone interviews Neno, Malawi. Out 126 survey respondents, 71% were patients, 29% caregivers. Twenty-two percent respondents had received at least one dose...
Introduction The Package of Essential Noncommunicable Disease Interventions—Plus (PEN-Plus) is a strategy decentralising care for severe non-communicable diseases (NCDs) including type 1 diabetes, rheumatic heart disease and sickle cell disease, to increase access care. In the PEN-Plus model, mid-level clinicians in intermediary facilities low lower middle income countries are trained provide integrated conditions where services traditionally were only available at tertiary referral...
To assess the feasibility and change in clinical outcomes associated with continuous glucose monitoring (CGM) use among a rural population Malawi living type 1 diabetes. A 2:1 open randomised controlled trial. Two Partners In Health-supported Ministry of Health-run first-level district hospitals Neno, Malawi. 45 people diabetes (PLWT1D). Participants were randomly assigned to Dexcom G6 CGM (n=30) or usual care (UC) (n=15) consisting Safe-Accu monitors strips. Both arms received education....
<strong>Background:</strong> Non-communicable diseases (NCDs) are a leading cause of worldwide morbidity and mortality, yet access to care in lower-income countries is limited. Rural communities, where poverty levels high, feel the greatest burden. In Malawi, as elsewhere African region, it particularly challenging for patients rural districts obtain locally endemic severe NCDs such type 1 diabetes, rheumatic heart disease, sickle cell disease. The Package Essential NCD Interventions – Plus...
Self-monitoring of blood glucose (SMBG) is a widely accepted standard practice for management insulin-dependentdiabetes, yet largely unavailable in rural sub-Saharan Africa (SSA). This prospective cohort study the first known report ofimplementation SMBG rural, low-income country setting.To evaluate adherence and change clinical outcomes with implementation at two hospitals Neno, Malawi.Forty-eight patients type 1 insulin-dependent 2 diabetes were trained to use glucometers logbooks....
Cardiovascular disease (CVD) is a major cause of death in Malawi. In rural districts, heart failure (HF) care limited and provided by non-physicians. The causes patient outcomes HF Africa are largely unknown. our study, non-physician providers performed focused cardiac ultrasound (FOCUS) for diagnosis longitudinal clinical follow-up Neno,
The prevalence of type 1 diabetes (T1D) is increasing in low-income countries including Malawi. In this setting, care frequently impacted by challenges diagnosis and management. Access to high-quality T1D remains limited Malawi, with fairly low availability high cost insulin other supplies diagnostics, lack knowledge, absence readily accessible guidelines. the Neno district, Partners Health established advanced clinics at district hospitals provide comprehensive, free for noncommunicable...
Background Globally, an estimated five percent of adults have major depressive disorder. However, little is known about the relationship between these individuals' symptoms and their household members' mental health well-being.Objectives We aimed to investigate prevalence predictors among adult members patients living with disorder in Neno District, Malawi.Methods As part a cluster randomized controlled trial providing depression care disorder, we conducted surveys patients' (n = 236)...
Internalized stigma is common among individuals with sexually transmitted infections such as HIV and those mental health conditions major depressive disorder (MDD). As part of a cluster randomized trial, we investigated the prevalence correlates internalized adults living comorbid MDD in rural Malawi (n = 339). We found heightened toward illness cohort: more than half respondents (54%) endorsed negative perceptions associated each condition. HIV-related was higher no education (
Introduction The majority of people living with type 1 diabetes (PLWT1D) struggle to access high-quality care in low-income countries (LICs), and lack technologies, including continuous glucose monitoring (CGM), that are considered standard high resource settings. To our knowledge, there no studies the literature describing feasibility or effectiveness CGM at rural first-level hospitals LICs. Methods analysis This is a 3-month, 2:1 open-randomised trial assess clinical outcomes introducing...
Malawi is a low-income country in sub-Saharan Africa that has limited resources to address significant burden of disease-including HIV/AIDS. Additionally, depression leading cause disability the but largely remains undiagnosed and untreated. The lack cost-effective, scalable solutions fundamental barrier expanding treatment. Against this backdrop, one major success been scale-up network more than 700 HIV clinics, with over half million patients enrolled antiretroviral therapy (ART). As...
Abstract Purpose Cytomegalovirus (CMV) is associated with significant morbidity and mortality among solid organ transplant (SOT) recipients. Strategies for CMV prevention include universal prophylaxis or preemptive approach. We aimed to evaluate the optimal Methods performed a systematic review meta-analysis of randomized controlled trials comparing versus therapy in SOT. The primary outcome was disease. Subgroup analysis outcomes D+ R− patients performed. Results Nine have met inclusion...
COVID-19-related knowledge and behaviors remain essential for controlling the spread of disease, especially among vulnerable patients with advanced, chronic diseases. We prospectively assessed changes over 11 months in testing, knowledge, non-communicable diseases rural Malawi using four rounds telephone interviews between November 2020 to October 2021. The most commonly reported risks included visiting health facilities (35-49%), attending mass gatherings (33-36%), travelling outside...
Perinatal depression contributes significantly to morbidity and mortality of women children in low- middle-income countries. However, due low resources little evidence on the impact screening treatment, few interventions are offered. Our study aims assess feasibility symptoms with treatment rural Malawi. Screening for was conducted using Patient Health Questionnaire 2 (PHQ-2) PHQ-9. Women identified have moderate severe were treated through a group counselling intervention—WHO Group Problem...
Abstract Background The prevalence of type 1 diabetes (T1D) is thought to be growing in low-income countries such as Malawi, despite a lack epidemiological data and published literature many areas. In countries, T1D care frequently impacted by challenges diagnosis management, including misdiagnosis access insulin, which can increase severe complications affect outcomes. Access high-quality remains limited with fairly low availability high cost insulin well other supplies diagnostics,...
Abstract Objective To assess changes over time in COVID-19 knowledge, risks, symptoms, testing, and infection prevention practices among patients with complex non-communicable disease (NCD) receiving care at Neno District Lisungwi Community Hospitals, Malawi. Design participants We conducted a prospective open cohort study using telephone-based data collection enrolled NCD clinics. four rounds of between November 2020 October 2021. Setting Rural southwestern Malawi which has population 150,...