A5044474605- Diabetes Management and Research
- Diabetes and associated disorders
- Toxic Organic Pollutants Impact
- Pesticide Exposure and Toxicity
- Heavy Metal Exposure and Toxicity
- Chronic Disease Management Strategies
- Diabetes Management and Education
- Pancreatic function and diabetes
- Air Quality and Health Impacts
- Effects and risks of endocrine disrupting chemicals
- Paraoxonase enzyme and polymorphisms
- Memory and Neural Mechanisms
- Per- and polyfluoroalkyl substances research
- Therapeutic Uses of Natural Elements
- Antiplatelet Therapy and Cardiovascular Diseases
- Breastfeeding Practices and Influences
- Neurobiology of Language and Bilingualism
- Carcinogens and Genotoxicity Assessment
- Adolescent Sexual and Reproductive Health
- Health Systems, Economic Evaluations, Quality of Life
- Adolescent and Pediatric Healthcare
- Atrial Fibrillation Management and Outcomes
- Environmental Education and Sustainability
- Memory Processes and Influences
- Chemical Analysis and Environmental Impact
Brigham and Women's Hospital
2021-2024
Partners In Health
2021-2024
University of California, Berkeley
2006-2017
Center for Environmental Health
2011-2017
Battelle
2012
University of California System
2011
Organophosphate (OP) pesticides are neurotoxic at high doses. Few studies have examined whether chronic exposure lower levels could adversely affect children's cognitive development.We associations between prenatal and postnatal to OP abilities in school-age children.We conducted a birth cohort study (Center for the Health Assessment of Mothers Children Salinas study) among predominantly Latino farmworker families from an agricultural community California. We assessed by measuring dialkyl...
California children's exposures to polybrominated diphenyl ether flame retardants (PBDEs) are among the highest worldwide. PBDEs known endocrine disruptors and neurotoxicants in animals.Here we investigate relation of utero child PBDE exposure neurobehavioral development participants CHAMACOS (Center for Health Assessment Mothers Children Salinas), a birth cohort.We measured maternal prenatal serum samples examined association concentrations with attention, motor functioning, cognition at 5...
Abstract Numerous behavioral studies have suggested that normal aging has deleterious effects on episodic memory and recollection is disproportionately impaired relative to familiarity-based recognition. However, there a wide degree of variability in performance within the population this generalization may not apply all elderly adults. Here we investigated these issues by using event-related potentials (ERPs) measure neural correlates familiarity older adults with recognition was equivalent...
Currently, there is no nationally representative human milk biomonitoring program in the United States (U.S.) and studies have reported non-persistent pesticides of U.S. women. In this pilot study we developed a multiresidue laboratory method to measure persistent polychlorinated biphenyl (PCB) congeners samples from women residing agricultural region Salinas, CA (n = 13) urban San Francisco Bay Area, 21). Samples were collected 2002–2007. Median concentrations pg g−1 among women,...
Objectives The purpose of this qualitative study is to describe the acceptability and appropriateness continuous glucose monitoring (CGM) in people living with type 1 diabetes (PLWT1D) at first-level (district) hospitals Malawi. Design We conducted semistructured interviews among PLWT1D healthcare providers participating study. Standardised interview guides elicited perspectives on CGM use for their providers, provider effectiveness Data were coded using Dedoose software analysed a thematic...
Introduction While epidemiological data for type 1 diabetes (T1D) in low/middle-income countries, and particularly low-income countries (LICs) including Liberia is lacking, prevalence LICs thought to be increasing. T1D care often impacted by challenges diagnosis management. These challenges, misdiagnosis access insulin, can affect outcomes frequency of severe complications. Despite the nature growing burden sub-Saharan Africa, little currently known about impact on patients caregivers...
To assess the feasibility and change in clinical outcomes associated with continuous glucose monitoring (CGM) use among a rural population Malawi living type 1 diabetes. A 2:1 open randomised controlled trial. Two Partners In Health-supported Ministry of Health-run first-level district hospitals Neno, Malawi. 45 people diabetes (PLWT1D). Participants were randomly assigned to Dexcom G6 CGM (n=30) or usual care (UC) (n=15) consisting Safe-Accu monitors strips. Both arms received education....
Abstract Although pica, the craving and purposive consumption of non‐food substances, is common among many populations, especially during pregnancy, health consequences are not well understood. Further, very little known about pica M exican populations in U nited S tates exico. Therefore, we conducted formative research to understand this understudied population. Our objectives were identify frequency types behaviours, perceived aetiologies ascertain if behaviour was enough warrant a larger...
The prevalence of type 1 diabetes (T1D) is increasing in low-income countries including Malawi. In this setting, care frequently impacted by challenges diagnosis and management. Access to high-quality T1D remains limited Malawi, with fairly low availability high cost insulin other supplies diagnostics, lack knowledge, absence readily accessible guidelines. the Neno district, Partners Health established advanced clinics at district hospitals provide comprehensive, free for noncommunicable...
Introduction The majority of people living with type 1 diabetes (PLWT1D) struggle to access high-quality care in low-income countries (LICs), and lack technologies, including continuous glucose monitoring (CGM), that are considered standard high resource settings. To our knowledge, there no studies the literature describing feasibility or effectiveness CGM at rural first-level hospitals LICs. Methods analysis This is a 3-month, 2:1 open-randomised trial assess clinical outcomes introducing...
Achieving glycaemic targets for people living with diabetes (PLWD) is challenging, especially in settings limited resources. Programmes need to address gaps knowledge, skills and self-management. Diabetes Self-Management Education (DSME) an evidence-based intervention educate empower PLWD improve self-management activities. This protocol describes a pilot study assessing the feasibility, acceptability effect on clinical outcomes of implementing DSME clinics caring insulin-dependent...
Background and Aims: Organophosphate (OP) pesticides are acute neurotoxicants. In the US, they widely used in agriculture. We present associations of OP exposure during pregnancy neurodevelopment children CHAMACOS study, a longitudinal birth cohort study primarily Latino farmworker families living California. Methods: enrolled 601 pregnant women conducted neurodevelopmental assessments their at 1 6 months 1, 2, 3.5, 5, 7, 9 years. The currently undergoing 10.5 year assessment. pesticide...
Quirós-Alcalá, Lesliam; Harley, Kim; Kogut, Katherine; Trujillo, Celina; Calderon, Norma; Vedar, Michelle; Johnson, Caroline; Bradman, Asa; Nishioka, Marcia; Eskenazi, Brenda Author Information
Abstract Background The prevalence of type 1 diabetes (T1D) is thought to be growing in low-income countries such as Malawi, despite a lack epidemiological data and published literature many areas. In countries, T1D care frequently impacted by challenges diagnosis management, including misdiagnosis access insulin, which can increase severe complications affect outcomes. Access high-quality remains limited with fairly low availability high cost insulin well other supplies diagnostics,...