Stüve-Wiedemann syndrome (SWS) is a rare, severe autosomal recessive disorder (#OMIM 601559) caused by pathogenic variants in the LIFR gene. It characterized skeletal dysplasia and dysautonomia carries high mortality rate infancy, which decreases significantly after age of 2. Detailed case descriptions enhance understanding this rare condition. We report male, full-term infant born to consanguineous Yemeni parents with no family history genetic disorders. Prenatal ultrasound revealed short,...

Lumpy skin disease (LSD) is a highly infectious endemic viral of cattle in Africa and the Middle East. The objectives this study were to assess histopathological changes infected with LSD measure serum malondialdehyde (MDA - oxidant) total anti-oxidant capacity (TAC anti-oxidant), trace elements (zinc, copper, iron), cytokines (interleukin [IL]-1β, IL-6, tumor necrosis factor-alpha [TNF-α]), haptoglobin (Hp), amyloid A (SAA), aspartate aminotransferase (AST), alanine (ALT), creatine...

The goals of this study were to determine serum protein fractions, acute phase proteins and inflammatory cytokine concentrations, as well histological alterations, phagocytic activity, index in sheep with pneumonia.An overall 50 adult assessed categorized into control healthy (Group 1, n=20), pneumonia 2, n = 30).Pneumonia is medically diagnosed by physical examinations, ultrasonography, histopathological investigation.Serum fraction concentrations measured electrophoresis, while biomarkers...

Equine herpesvirus type 1 (EHV-1) causes rhinopneumonitis, abortion, and neurological outbreaks (equine myeloencephalopathy, EHM) in horses. EHV-1 also lethal encephalitis small laboratory animals such as mice hamsters experimentally. ORF76 is a homolog of HSV-1 US9, which kinase. Starting with an bacterial artificial chromosome clone neuropathogenic strain Ab4p (pAb4p BAC), we constructed deletion mutant (Ab4p∆ORF76) by replacing the rpsLneo gene. Deletion had no influence on replication,...

It is well established that dendritic cells and macrophages play a role in antigen presentation to B T shaping cell responses via cytokines they produce. We have previously reported depletion of neutrophils improves the production mucosal IgA after sublingual immunization with Bacillus anthracis edema toxin as adjuvant. These past studies also demonstrated an inverse correlation exists between number by cells. Using specific inhibitors elastase, we addressed whether elastase activity...

The goals of this study were to measure serum vitamin A (retinol) and E (α-tocopherol) trace elements concentrations (copper, zinc selenium) during diseases condition determine their association with hematological parameters immune status hospitalized camels. total 95 dromedary camels [healthy (n=65); (n=30)] included in study. Vitamin significantly lower than apparently healthy ones (P<0.05). Hospitalized had selenium compared E, copper, positively correlated phagocytic activity likelihood...

Staphylococcus pyoderma is a common problem in dogs that need novel treatment rather than antibiotic therapy. The aim of this study was to investigate the therapeutic efficacy, anti-inflammatory, and antioxidative properties Aloe vera (Aloe barbadensis) gel ointment on dogs' compared gentamicin ointment.The inhibition zone A. extract 20% 40% 1% against aureus determined well diffusion agar. Twenty Baladi local breed were used as control negative group before intradermal inoculation with 105...

Bovine tuberculosis represents one of the very important infectious diseases in Egypt and  world. It has zoonotic importance causes severe economic losses. Accurate rapid diagnosis considered as milestone for control disease. In this study ELISA technique was used for confirmation positive reactors cows that tested with single intradermal tuberculin test, to detect false reactors. PPD ST.CF antigens have been two different coatingantigens technique. 3747 cattle from dairy farms five...

The present study was carried out to evaluate the diagnostic value of inflammatory biomarkers on diseased camels via exploring possible effects oxidants and antioxidants status in addition characterizing profiles acute phase proteins cytokines. Forty-eight adult male female dromedary (Camelus dromedaries) were examined, according general health conditions, clinical laboratory diagnosis they split into 3 groups. Group 1: Included 20 apparently healthy act as a control group, 2: 12 suffered...

<title>Abstract</title> <bold>Background:</bold> The goal of this study was to evaluate the therapeutic efficacy silymarin against sheep pneumonia utilizing clinical, biochemical and metabolomics approaches. <bold>Methods:</bold> Fifty adult male Barki were divided into two groups based on their health status. Group 1 included healthy (n = 10); 2 sick with clinical evidence 40), which further classified four subgroups treatment protocols: subgroup (SG1) given traditional treatment; (SG2)...

Equine herpesvirus type 1 (EHV-1) causes rhinopneumonitis, abortion and neurological outbreaks (equine myeloencephalopathy, EHM) in horses. EHV-1 also lethal encephalitis laboratory small animals such as mice hamsters experimentally. ORF76 is a homologue of HSV-1 US9, which kinase. Starting with an bacterial artificial chromosome clone neuropathogenic strain Ab4p (pAb4p BAC), we constructed deletion mutant (Ab4p∆ORF76) by replacing the rpsLneo gene. Deletion had no influence on replication,...

Abstract El-Khodery, S.A., Nassif, M.N. and Hassan, H.Y. 2010. Two dimension echocardiography in normal buffaloes (Bubalus bubalis). J. Appl. Anim. Res., 37: 57–61. To study ultrasonographic appearance dimensions of the heart 13 adult, non-pregnant (3–7 years, 419.6±24.9 kg) were examined, (in standing position) at 3–6 intercostal space on both sides thorax using 3.5-MHz convex transducer. All chambers clearly visualized caudal long axis view from sides. Right left ventricles short right...

Acute ruminal acidosis is a common problem in ruminants that feed on high amount of concentrates and has been associated with inflammatory condition the rumen metabolic acidosis. The goals this study were to measure acute phase proteins (haptoglobin C-reactive protein concentrations), biochemical changes determine their association mortality sheep A total 25 included divided two groups [one group suffered from (n=15) another control healthy (n=10)]. Haptoglobin C- reactive (CRP)...

To evaluate the nasal histopathological and metabolic effects of administratio n intranasal insulin (INI) in type 2 diabetic (T2D) individuals. A total 51 adult male T2D patients were divided into 4 groups: group I received INI azone, II INI, azone polyacrylic acid, III IV, every or acid separately. Basal mucosal biopsy oral glucose tolerance test (OGTT) performed for all patients. On second day, fasting blood samples collected, then spray was administered. The same administrations given...

Pyoderma is common in dogs, and its treatment requires a novel medication rather than antibiotic therapy. This study aimed to determine the biochemical histopathological changes associated with topical application of Aloe vera 20% 40% ointments, compared gentamicin 0.1% ointment, dogs suffering from Staphylococcus aureus pyoderma.Serum skin samples were collected negative control group before inducing pyoderma other subdivided groups on 3rd, 7th, 10th, 14th days post-inoculation for...