A5016624581- Photoreceptor and optogenetics research
- Neuroscience and Neural Engineering
- Neural dynamics and brain function
- CCD and CMOS Imaging Sensors
- Optical Imaging and Spectroscopy Techniques
- Molecular Communication and Nanonetworks
Columbia University
2022-2024
New York Proton Center
2023
Optical neurotechnologies use light to interface with neurons and can monitor manipulate neural activity high spatial-temporal precision over large cortical extents. While there has been significant progress in miniaturizing microscope for head-mounted configurations, these existing devices are still very bulky could never be fully implanted. Any viable translation of technologies human will require a much more noninvasive, implantable form factor. Here, we leverage advances microelectronics...
One of the goals neuroengineering is to establish high-bandwidth, fully implantable, and minimally invasive wireless neural interfaces that help interrogate circuits in freely moving socially behaving animals. Optical offer advantages over electrophysiological techniques such as cell-type specificity, low cross-talk bidirectionality, wide field-of-view (FoV). While most optical to-date have taken form bulky "mini-scopes", recent advances shown promise achieving high-resolution,...
We demonstrate a fully implantable optoelectronic neural interface device featuring an array of single-photon avalanche photodiode (SPAD) detectors with global shutter and monolithically integrated flip-chip bonded micro-LEDs (µLED) for fluorescence excitation optogenetic stimulation. The is optical filters lensless computation mask to create 200-µm-thick device. To enable the shutter, area-efficient 10b roll-over counter used in-pixel. With phase unwrapping algorithm, these counters can be...