A5025453718- Catalytic C–H Functionalization Methods
- Radical Photochemical Reactions
- Sulfur-Based Synthesis Techniques
- Chemical Synthesis and Reactions
- Crystallization and Solubility Studies
- Asymmetric Hydrogenation and Catalysis
- Synthetic Organic Chemistry Methods
- Computational Drug Discovery Methods
- Chemical synthesis and alkaloids
- Catalytic Cross-Coupling Reactions
- Molecular spectroscopy and chirality
- X-ray Diffraction in Crystallography
- Oxidative Organic Chemistry Reactions
- Cyclopropane Reaction Mechanisms
- Alkaloids: synthesis and pharmacology
- Axial and Atropisomeric Chirality Synthesis
- Microwave-Assisted Synthesis and Applications
- Fluorine in Organic Chemistry
- Organophosphorus compounds synthesis
École Nationale Supérieure de Chimie de Montpellier
2022-2024
Université de Montpellier
2022-2024
Centre National de la Recherche Scientifique
2019-2024
Chimie et Interdisciplinarité, Synthèse, Analyse, Modélisation
2019
Nantes Université
2019
A user-friendly approach is presented to sidestep the venerable Grignard addition unactivated ketones access tertiary alcohols by reversing polarity of disconnection. In this work a ketone instead acts as nucleophile when adding simple olefins accomplish same overall transformation. The scope coupling broad enabled using an electrochemical approach, and reaction scalable, chemoselective, requires no precaution exclude air or water. Multiple applications demonstrate simplifying nature on...
We report herein a new catalytic strategy towards asymmetric photooxygenation of β‐dicarbonyl compounds. Our method is based on the synthesis bifunctional photosensitizer composed quinine organocatalyst grafted to an iodo‐BODIPY framework capable generating singlet oxygen. The moiety serves both interact with substrate for promoting and deactivate oxygen in absence substrate. prepared was subsequently applied oxygenation series compounds under green light irradiation. Control experiments...
<div><div><div><p>A user-friendly approach to sidestep the venerable Grignard addition unactivated ketones access tertiary alcohols by reversing polarity of disconnection. In this work a ketone instead acts as nucleophile when adding simple olefins accomplish same overall transformation. The scope coupling is broad enabled using an electrochemical and reaction scalable, chemoselective, requires no precaution exclude air or water. Multiple applications demonstrate...
Abstract P III /P V redox cycling has recently emerged as a valuable strategy to minimized the chemical waste generated by phosphine‐mediated reaction, well enabling asymmetric transformation. In this article, we detail our contribution field designing series of diversely functionalized, electron‐rich bridgehead phosphine oxides with structural features that make them well‐suited organocatalysts. Their catalytic performance been assessed in various model reactions, including Wittig or...
In the last three decades, reacting sterically congested ortho-substituted arenes to form atropochiral biaryls is an appealing venture and a challenging subject that has garnered significant attention. Therefore, there interest in developing methods prepare these compounds. this study, efficient approach produce new class 2,2' disubstituted bridgehead phosphine oxides with unusual topology exceptional conformational stability presented. Our methodology demonstrates depending on substitution...
A user-friendly approach to sidestep the venerable Grignard addition unactivated ketones access tertiary alcohols by reversing polarity of disconnection. In this work a ketone instead acts as nucleophile when adding simple olefins accomplish same overall transformation. The scope coupling is broad enabled using an electrochemical and reaction scalable, chemoselective, requires no precaution exclude air or water. Multiple applications demonstrate simplifying nature on multi-step synthesis...
A simple and rapid microwave-assisted protocol for the selective alkaline hydrolysis of phosphonate diesters has been developed to access phosphonic acid monoesters, which are otherwise difficult obtain by conventional approaches.