Endometriosis is a condition affecting reproductive-age women and associated with dysmenorrhea, pelvic organs dysfunction, pain, infertility. The real epidemiology of endometriosis remains underestimated. No data are available on prevalence in Kazakhstan. Therefore, the aim this was to investigate epidemiology, complications, surgical management approach, outcomes Kazakhstan by analyzing large-scale Kazakhstani healthcare from Unified Nationwide Electronic Health System (UNEHS). A...

A Global Burden of Disease (GBD) study reported that 9.6 million years lived with disability (YLDs) were lost due to hip and knee osteoarthritis (KOA) in 2017. Although the GBD presents disease burden at global level, there is no information on any Central Asian country. This aims investigate epidemiology Kazakhstan. The data 56,895 people KOA between 2014-2020 was derived from Unified National Electronic Health System Kazakhstan retrospectively analyzed. majority cohort (76%) women, Kazakh...

According to the Global Burden of Disease (GBD) study, chronic kidney disease (CKD) was prevalent in 697.5 million individuals worldwide 2017. By 2040, it is anticipated that CKD will rank as fifth most common cause death. This study aims examine epidemiology Kazakhstan and project future trends prevalence mortality by 2030. The retrospective analysis performed on a database acquired from Unified National Electronic Health System for 703,122 patients with between 2014 2020. During...

This study aims to estimate tuberculosis (TB) incidence, mortality rates and survival HRs in Kazakhstan, using large-scale administrative health data records during 2014-2019.A retrospective cohort study.Data for patients with TB Kazakhstan 2014-2019, reported the Unified National Electronic Healthcare System.Patients (ICD-10 (The International Classification of Diseases, 10th revision) codes: A15-A19).Demographic factors, diagnoses comorbidities were analysed descriptive, bivariate...

The in-depth epidemiology of hypertension has not been studied in Kazakhstan (KZ) yet. We aimed to investigate the crude; age and sex standardized prevalence, incidence, all-cause mortality rate among hypertensive patients using a large-scale Unified National Electronic Health System (UNEHS) for period 2014-2019. Hypertension was defined based on ICD-10 codes (ICD-code: I10; I11; I12; I13). Of 1,908,419 patients, 1,186,706 (62.18%) were females 721,713 (37.82%) males. majority (56.3%) ethnic...

Abstract There is a lack of information on the epidemiology acute ischemic stroke (AIS), intracerebral hemorrhage (ICH), and subarachnoid (SAH) in developing countries. This research presents incidence mortality rates patients based hospital admission discharge status one Central Asian countries by analysis large-scale healthcare data. The registry data 177,947 admitted to with diagnosis between 2014 2019 were extracted from National Electronic Health System Kazakhstan. We provide...

Background The comprehensive epidemiology and impact of climate on viral meningitis (VM) in Kazakhstan are unknown. We aimed to study the incidence, in-hospital mortality influence climatic indicators VM from 2014 2019. Methods Nationwide electronic healthcare records were used explore this study. ICD-10 codes VM, demographics, hospital outcomes evaluated using descriptive statistics survival analysis. Results During 2014–2019 period, 10,251 patients with admitted hospital. 51.35% them...

Introduction: Preeclampsia is a severe multifactorial complication of pregnancy. Studies found associations between folate metabolism genes’ polymorphisms and preeclampsia. However, investigations in this field are limited among Asian populations. Thus, the study’s aim was to evaluate prevalence methionine synthase (MTR), reductase (MTRR), methylenetetrahydrofolate (MTHFR) ethnic Kazakh women with Methods: This retrospective study involving 4246 patients’ data for period 2018–2022....

HIV is a growing public health burden that threatens thousands of people in Kazakhstan. Countries around the world, including Kazakhstan, are facing significant problems predicting infection prevalence. It crucial to understand epidemiological trends infectious diseases and monitor prevalence long-term perspective. Thus, this study, we aimed forecast Kazakhstan for 10 years from 2020 2030 by using mathematical modeling time series analysis.We use statistical Autoregressive Integrated Moving...

Cardiovascular diseases contribute to premature mortality globally, resulting in substantial social and economic burdens. The Global Burden of Disease (GBD) Study reported that 2019 alone, heart attack strokes accounted for the deaths 18.6 million individuals. Ischemic diseases, including acute myocardial infarction (AMI), 182 disability-adjusted life years (DALYs) it is leading cause death worldwide.The aim this study present burden AMI Kazakhstan describe outcome hospitalized patients.The...

<b>Background: </b>Vaccine-preventable diseases such as pertussis, measles, and influenza remain among the most significant medical socioeconomic issues in Kazakhstan, despite vaccination achievements. Thus, here we aimed to analyze long-term dynamics provide information on current epidemiology of Kazakhstan.<br /> <b>Methods: </b>A retrospective analysis infectious was carried out using data from statistical collections for 2010-2020 Unified Payment System 2014...

Peripheral artery disease (PAD) is a global health concern associated with arterial narrowing or blockage, leading to significant morbidity and mortality. The aim of this study assess the burden trends in mortality utilizing nationwide administrative data. This retrospective utilized data from Unified National Electronic Healthcare System (UNEHS) 2014 2021. Patients meeting PAD criteria were included, demographic clinical analyzed. Cox regression Competing Risk Analysis assessed risks....

Tuberculosis (TB) is a highly contagious disease that remains global concern affecting numerous countries. Kazakhstan has been facing considerable challenges in TB prevention and treatment for decades. This study aims to understand transmission dynamics by developing comparing statistical deterministic models: Seasonal Autoregressive Integrated Moving Average (SARIMA) the basic Susceptible-Infected-Recovered (SIR). data from 2014 2019 were collected Unified National Electronic Health System...

Cancer remains a leading cause of death both globally and in Kazakhstan, making it crucial to track its mortality trends. This study aimed investigate cancer trends from 2014 2022 Kazakhstan.

<b>Background and objective: </b>Hepatitis B virus (HBV) hepatitis C (HCV) are major contributors to chronic viral (CVH), leading significant global health mortality. This study aims predict the one-year mortality in patients with CVH using their demographics records.<br /> <b>Methods: </b>Clinical data from 82,700 diagnosed HBV or HCV between January 2014 December 2019 was analyzed. We developed a machine learning (ML) platform based on six broad categories...

Abstract Background Heart failure (HF) affected 64.3 million people worldwide and contributed to 9.9 years lived with disability globally in 2017. Despite its global relevance, there is a lack of comprehensive statistics on the prevalence, incidence, burden HF developing Central Asian countries. This study aims fill gap present data for Kazakhstan, largest country. Methods cases were identified through Unified National Electronic Healthcare System records 2014-2021 using appropriate ICD-10...

Abstract Tuberculosis (TB) is a major cause of morbidity and mortality worldwide. The seasonal autoregressive integrated moving average (SARIMA) model widely used for forecasting infectious disease incidence, including TB. However, there lack comprehensive research on TB epidemiology predictions the future in Kazakhstan. Therefore, this study adopted time series analysis 72 monthly observations reported cases Kazakhstan from 2014-2019. health data 2014-2019 obtained large-scale...

<b>Background</b><b>: </b>According to the National infectious disease monitoring report, there is a fluctuating pattern of incidence chickenpox in country, but are no studies reporting epidemiological situation Kazakhstan. There discernable association varicella epidemiology with climate, particularly temperature dependency. We aimed analyze and seasonality absence universal vaccination Kazakhstan.<br /> <b>M</b><b>aterial...

Background: Cardiovascular diseases contribute to premature death worldwide which leads social and economic loss. According the Global Burden of Disease Study data, in Kazakhstan, 714,104 disability-adjusted life years (DALYs) were lost between 1990 2017 from ischemic heart diseases. The aim this study is analyze separately burden acute myocardial infarction (AMI) Kazakhstan describe outcome hospitalized patients.Methods: data 79,172 people admitted hospital with ICD-10 diagnosis I21...