A5010563365- Escherichia coli research studies
- Antibiotic Resistance in Bacteria
- Mycobacterium research and diagnosis
- Infectious Diseases and Mycology
- Enterobacteriaceae and Cronobacter Research
- Tuberculosis Research and Epidemiology
- Gene expression and cancer classification
- Fungal Infections and Studies
- Genetic Associations and Epidemiology
- RNA and protein synthesis mechanisms
- Diagnosis and treatment of tuberculosis
- Bioinformatics and Genomic Networks
- Evolution and Genetic Dynamics
- Genomics and Phylogenetic Studies
- Salmonella and Campylobacter epidemiology
Helmholtz Centre for Infection Research
2023-2025
Center for Experimental and Clinical Infection Research
2023-2025
Medizinische Hochschule Hannover
2023-2025
Centre de Recerca en Sanitat Animal
2022-2024
Universitat Autònoma de Barcelona
2024
Escherichia coli is both a highly prevalent commensal and major opportunistic pathogen causing bloodstream infections (BSI). A systematic analysis characterizing the genomic determinants of extra-intestinal pathogenic vs. isolates in human populations, which could inform mechanisms pathogenesis, diagnostic, prevention treatment still lacking. We used collection 912 BSI 370 E . collected France over 17-year period (2000–2017). compared their pangenomes, genetic backgrounds (phylogroups, STs,...
Identifying genetic variants associated with bacterial phenotypes, such as virulence, host preference and antimicrobial resistance, has great potential for a better understanding of the mechanisms involved in these traits. The availability large collections genomes made genome-wide association studies (GWAS) common approach this purpose. need to employ multiple software tools data pre- postprocessing limits application methods by experienced bioinformaticians. To address issue, we have...
Abstract Escherichia coli is both a highly prevalent commensal and major opportunistic pathogen causing bloodstream infections (BSI). A systematic analysis characterizing the genomic determinants of extra-intestinal pathogenic vs. isolates in human populations, which could inform mechanisms pathogenesis, diagnostics, prevention treatment still lacking. We used collection 1282 BSI E. collected France over 17-year period (2000-2017) we compared their pangenomes, genetic backgrounds...
Voles are maintenance hosts of Mycobacterium microti. In line with the goal to eradicate tuberculosis (TB) in livestock, role this mycobacteria needs be assessed since it might interfere current M. bovis/M. caprae surveillance strategies. To better understand pathogenesis TB voles, an experimental infection model was set up reproduce microti laboratory Bank voles (Myodes glareolus). Two routes (intragastric and intraperitoneal) doses (105 106 CFU/0.1 mL) were assessed. culled at different...
Adiaspiromycosis is a nontransmissible infectious pulmonary disease caused by the inhalation of propagules from fungal species belonging to family Ajellomicetaceae, especially Emergomyces crescens. E. crescens has been recorded in broad number worldwide, with small burrowing mammals being considered main hosts for this environmental pathogen. Only handful studies on adiaspiromycosis European wildlife published date. We assessed occurrence wild rodents (Murinae and Arvicolinae) central...
Abstract Identifying genetic variants associated with bacterial phenotypes, such as virulence, host preference, and antimicrobial resistance, has great potential for a better understanding of the mechanisms involved in these traits. The availability large collections genomes made genome-wide association studies (GWAS) common approach this purpose. need to employ multiple software tools data pre- post-processing limits application methods by experienced bioinformaticians. To address issue, we...