Longxin Dong

ORCID: 0000-0002-6383-6476
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About
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Research Areas
  • Circular RNAs in diseases
  • Cancer-related molecular mechanisms research
  • Urinary Bladder and Prostate Research
  • MicroRNA in disease regulation
  • Urinary Tract Infections Management
  • Prostate Cancer Diagnosis and Treatment
  • RNA modifications and cancer
  • Nuts composition and effects
  • Tea Polyphenols and Effects
  • Prostate Cancer Treatment and Research
  • Pelvic floor disorders treatments
  • Diet, Metabolism, and Disease
  • Urinary and Genital Oncology Studies
  • Radiopharmaceutical Chemistry and Applications
  • Phytochemical and Pharmacological Studies
  • Bladder and Urothelial Cancer Treatments
  • Sunflower and Safflower Cultivation
  • Genital Health and Disease

Jiamusi University
2020-2022

First Affiliated Hospital of Jiamusi University
2020

Platycodin D (PD) is a major constituent of Platycodon grandiflorum and has multiple functions in disease control. This study focused on the function PD bladder cancer cell behaviors molecules involved. First, we administered to lines T24 5637 human uroepithelial line SV-HUC-1. Cell viability growth were evaluated using MTT, EdU, colony formation assays, apoptosis was determined Hoechst 33342 staining flow cytometry. The microRNAs (miRNAs) showing differential expression cells before after...

10.1590/1414-431x202010222 article EN cc-by Brazilian Journal of Medical and Biological Research 2021-01-01

Previous studies have reported that docetaxel combined prednisone (DP) has been used for the treatment of patients with hormone refractory prostate cancer (HRPC). However, its results are still inconsistent. Therefore, this study will synthesize latest evidence efficacy and safety DP HRPC.Cochrane Library, PUBMED, EMBASE, Web Science, CINAHL, CBM, CNKI be searched to identify randomized controlled trials published from their inception March 1, 2020, irrespective language publication time...

10.1097/md.0000000000020367 article EN Medicine 2020-05-28

This study will aim to appraise the efficacy and safety of pirarubicin for treatment patients with nonmuscle invasive bladder cancer (NMIBC).We perform a comprehensive literature search in MEDLINE, EMBASE, Cochrane Library, Scopus, PsycINFO, Web Science, Allied Complementary Medicine Database, Chinese Biomedical Literature China National Knowledge Infrastructure from their beginning February 29, 2020. All randomized controlled trials NMIBC be included regardless limitations related language...

10.1097/md.0000000000020415 article EN cc-by-nc Medicine 2020-06-03

This study will examine the effectiveness and safety of neuromuscular electrical stimulation (NMES) for treatment patients with interstitial cystitis (IC).We retrieve following electronic databases from their commencements to March 1, 2020 discover all related potential studies: MEDLINE, EMBASE, Cochrane Library, Web Science, Cumulative Index Nursing Allied Health Literature (CINAHL), China National Knowledge Infrastructure, Chinese Biomedical Database, Scientific Journal WANFANG Database....

10.1097/md.0000000000021088 article EN cc-by-nc Medicine 2020-07-09

Abstract Background This study will examine the effectiveness and safety of neuromuscular electrical stimulation (NMES) for treatment patients with interstitial cystitis (IC). Methods We retrieve following electronic databases from their commencements to March 1, 2020 discover all related potential studies: MEDLINE, EMBASE, Cochrane Library, Web Science, CINAHL, China National Knowledge Infrastructure, Chinese Biomedical Literature Database, Scientific Journal WANFANG Database. Randomized...

10.21203/rs.3.rs-27664/v1 preprint EN cc-by Research Square (Research Square) 2020-05-14

Abstract Background Clear cell renal carcinoma (CCRCC) is a prevalent urological with high metastatic risk. Circular RNAs (circRNAs) have been identified as effective diagnostic and therapeutic biomarkers for CCRCC. This research aims to disclose the involvement of circRNA ribosomal protein L23a (circ_RPL23A) in CCRCC, how it regulates carcinogenesis. Methods We performed quantitative real-time polymerase chain reaction (qRT-PCR) examine circ_RPL23A, microRNA-1233 (miR-1233) acetyl-coenzyme...

10.21203/rs.3.rs-18104/v2 preprint EN cc-by Research Square (Research Square) 2020-07-15

Abstract Background Clear cell renal carcinoma (CCRCC) is a prevalent urological with high metastatic risk. Circular RNAs (circRNAs) have been identified as effective diagnostic and therapeutic biomarkers for CCRCC. This research aims to disclose the involvement of circRNA ribosomal protein L23a (circ_RPL23A) in CCRCC, how it regulates carcinogenesis. Methods We performed quantitative real-time polymerase chain reaction (qRT-PCR) examine circ_RPL23A, microRNA-1233 (miR-1233) acetyl-coenzyme...

10.21203/rs.3.rs-18104/v1 preprint EN cc-by Research Square (Research Square) 2020-03-20
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