A5090261217- Circadian rhythm and melatonin
- Early Childhood Education and Development
- Cognitive Abilities and Testing
- Sleep and related disorders
- Cognitive and developmental aspects of mathematical skills
- Neuroscience, Education and Cognitive Function
- Intelligent Tutoring Systems and Adaptive Learning
- Child and Animal Learning Development
- Developmental and Educational Neuropsychology
- Sleep and Wakefulness Research
- Educational and Psychological Assessments
- Neuroscience and Neuropharmacology Research
- Educational Games and Gamification
- Innovative Teaching and Learning Methods
- Memory and Neural Mechanisms
- EEG and Brain-Computer Interfaces
- Photoreceptor and optogenetics research
- Online Learning and Analytics
- Neurogenesis and neuroplasticity mechanisms
- Education Methods and Practices
- Psychological and Temporal Perspectives Research
- Health, Education, and Physical Culture
- Education in Rural Contexts
- Cognitive Functions and Memory
- Food Security and Health in Diverse Populations
Ministerio de Ciencia, Tecnología e Innovación
2022-2024
Consejo Nacional de Investigaciones Científicas y Técnicas
2013-2024
Universidad Torcuato Di Tella
2014-2024
University of Buenos Aires
2004-2014
Fundación Ciencias Exactas y Naturales
2004-2014
Instituto de Neurociencias
2008-2009
Persistence is a characteristic attribute of long-term memories (LTMs). However, little known about the molecular mechanisms that mediate this process. We recently showed persistence LTM requires late protein synthesis- and BDNF-dependent phase in hippocampus. Here, we show intrahippocampal delivery BDNF reverses deficit memory caused by inhibition hippocampal synthesis. Importantly, demonstrate induces itself, transforming nonlasting trace into persistent one an ERK-dependent manner. Thus,...
Memory formation is a temporally graded process during which transcription and translation steps are required in the first hours after acquisition. Although persistence key characteristic of memory storage, its mechanisms scarcely characterized. Here, we show that long-lasting but not short-lived inhibitory avoidance long-term associated with delayed expression c-Fos hippocampus. Importantly, this late wave necessary for maintenance storage. Moreover, inhibition dorsal hippocampus 24 h...
Significance Executive functions (EF) imply processes critical for purposeful, goal-directed behavior. In children, evidence derived from laboratory measures indicates that training can improve EF. However, this hypothesis has never been explicitly examined based on real-world measures, especially of educational achievement. Here, we investigate whether a set computerized games might yield transfer low-socioeconomic status otherwise typically developing 6-y-olds in an intervention deployed...
Schools start early in the morning all over world, contrasting with adolescents' late chronotype. Interestingly, lower academic performance (i.e. grades or qualifications) was associated later chronotypes. However, it is unclear whether a direct effect of chronotype because students attend school too to perform at their best. Moreover, little known about how this affects students' success beyond grades. To address gap knowledge, we studied timing and affect grade retention repeat year)...
While poverty all over the world is more typical and extreme in rural contexts, interventions to improve cognition low socioeconomic status (SES) children are for most part based on studies conducted urban populations. This paper investigate how or settings affect child cognitive performance. Executive functions non-verbal intelligence performance, as well individual environmental information was obtained from 131 5-year-old children. For same level of SES, performed consistently worse than...
Abstract The misalignment between late chronotypes and early school start times affect health, performance psychological well-being of adolescents. Here we test whether, how, the baseline chronotype (i.e. at beginning secondary school) timing magnitude direction developmental change in during adolescence. We evaluated a sample Argentinian students (n = 259) who were randomly assigned to attend morning (07:45 a.m.–12:05 p.m.), afternoon (12:40 p.m.–05:00 p.m.) or evening (05:20 p.m.–09:40...
ABSTRACT Working memory and planning are fundamental cognitive skills supporting fluid reasoning. We show that 2 games train working in school‐aged children promote transfer to different tasks: an attentional test a reasoning test. also long‐term improvement of capacities 8‐year‐old after playing adaptive computer specifically tailored entrain these functions. capacity expanded from 5 7 items by using our games. Furthermore, steady progression the task indicates this can be trained rapidly....
Mate Marote is an open-access cognitive training software aimed at children between 4 and 8 years old. It consists of a set computerized games specifically tailored to train evaluate Executive Functions (EF), class processes critical for purposeful, goal-directed behavior, including working memory, planning, flexibility, inhibitory control. Since 2008, several studies were performed with this children’s own schools in interventions supervised in-person by scientists. After 2015, we...
ABSTRACT Pedagogy is the science and art of teaching. Each generation needs to explore history, theory, practice teacher–student interaction. Here we pave path develop a that explores cognitive physiological processes involved in human capacity communicate knowledge through We review examples from our previous work this research area discuss reveal cerebral mechanisms by which teach, unfolding complex operation such as teaching its constituents components.
Two thousand four hundred years ago Socrates gave a remarkable lesson of geometry, perhaps the first detailed record pedagogical method in vivo history [ Plato. (2008) . Apología de Sócrates. Menón. Crátilo Madrid: Alianza Editorial]. asked Meno's slave 50 questions requiring simple additions or multiplications. At end student discovered by himself how to duplicate square using diagonal given one as side new square. We studied empirically reproducibility this dialogue educated adults and...
Glutamate is the main excitatory neurotransmitter in retina, but it neurotoxic when present excessive amounts. The metabolic dependence of glutamatergic neurons upon glia via glutamate/glutamine cycle to provide precursor for glutamate well established. Since melatonin has been shown be neuroprotective several systems, report, its effect on activity was examined golden hamster retina. Melatonin (0.1-10 nM) significantly increased retinal glutamine synthetase did not affect L-glutamine...
Early childhood is a period characterized by the rapid development of several cognitive abilities known as executive functions (EFs), required for all kinds learning and adaptive behavior. Like other aspects development, both positive detrimental environmental conditions can have potential impact on EF maturation. For instance, an improvement in usually reported when children engage activities that gradually systematically challenge them. Mate Marote free online platform with videogames...
Executive functions are a class of cognitive processes critical for purposeful goal-directed behavior. Cognitive training is the adequate stimulation executive and has been extensively studied applied more than 20 years. However, there still lack solid consensus in scientific community about its potential to elicit consistent improvements untrained domains. Individual differences considered one most important factors inconsistent reports on benefits, as functioning both genetic...
Abstract Seventy‐three children between 6 and 7 years of age were presented with a problem having ambiguous subgoal ordering. Performance in this task showed reliable fingerprints: (a) non‐monotonic dependence performance as function the distance beginning end‐states problem, (b) very high levels when first move was correct, (c) states which accuracy significantly below chance. These features are consistent non‐Markov planning agent, an inherently inertial decision process, that uses...
Human circadian rhythms are entrained by the environmental light-dark cycle. In this study we have recorded diurnal and seasonal variations in a Mapuche native community of Neuquén (Patagonia, Argentina), where variables including photoperiod, temperature rainfall vary substantially throughout year could be considered as potential zeitgebers human rhythmicity. We analyzed patterns disease medical visits year. They exhibited clear peak after winter, while paramedical appeared to stable...
ABSTRACT In March 2012, 30 faculty and 49 students from all over the world met in El Calafate, Argentina, during two intense weeks. It was second Latin American School for Education, Cognitive, Neural Sciences (LASchool), sponsored by James S. McDonnell Foundation. The LA seeks to critically examine research findings potentially relevant development, design, implementation of effective educational practices, foster a new generation researchers able operate at interface between education...