Neural architecture search (NAS) enables researchers to automatically explore broad design spaces in order improve efficiency of neural networks. This is especially important the case on-device deployment, where improvements accuracy should be balanced out with computational demands a model. In practice, performance metrics model are computationally expensive obtain. Previous work uses proxy (e.g., number operations) or layer-wise measurement network layers estimate end-to-end hardware but...

This study introduces environmentally-friendly nanocellulose-based membranes for AZO dye (methylene blue, MB) removal from wastewater. These membranes, made of cellulose nanocrystals (CNCs), carboxymethyl (CMC), zeolite, and citric acid, aim to offer eco-friendly water treatment solutions. CNCs, obtained sugarcane bagasse, act as the foundational material membranes. The aims investigate both composition (CMC/CNC/zeolite/citric acid) critical adsorption factors (initial MB concentration,...

Gastric ulcer is sores that form in the stomach mucosal layer because of erosion caused by high acid secretion and excessive use non-steroidal anti-inflammatory drugs. Prodigiosins (PdGs) are red-pigmented secondary metabolites produced bacteria, including actinomycetes. Butylcycloheptylprodigiosin (1) undecylprodigiosin (2) were identified isolated from a crude extract actinomycete RA2 Red Sea Sponge Spheciospongia mastoidea. Chemical structure 1 2 was determined NMR mass spectroscopy....

Abstract Worldwide, epilepsy is the second most prevalent neurological disorder. Disappointingly, various adverse effects are being observed with currently used antiepileptic drugs. Nanomedicine represents an effective strategy to overcome these limitations a better central drug delivery. Hence, our work aimed unravel efficacy of rutin (Rut) loaded selenium nanoparticles (SeNPs) against pentylenetetrazole (PTZ)-challenged mice. Ten days before PTZ (60 mg·kg −1 ) intraperitoneal injection,...

2-(2-Hydroxyethylamino) ethanol (EA), dodecanoic acid (DA), and a freshly prepared ionic liquid named bis(2-hydroxyethyl) ammonium dodecanoate (ADD) were exercised as mitigators towards the corrosion of aluminum production hydrogen in 2.0 M HCl. The study was performed by gravimetry, gasometry, potential-time measurements, electrochemical methods. examined concentration range such inhibitors varied between 5×10-6M 5×10-3M. amount generated is enhanced with temperature lowered increasing...

ABSTRACT The biosynthetic gene cluster for the aromatic polyketide steffimycin of anthracycline family has been cloned and characterized from “ Streptomyces steffisburgensis ” NRRL 3193. Sequence analysis a 42.8-kbp DNA region revealed presence 36 open reading frames (ORFs) (one them incomplete), 24 which, spanning 26.5 kb, are probably involved in biosynthesis. They code all activities required biosynthesis, tailoring, regulation, resistance but show no evidence genes l -rhamnose...

Three new phenazine derivatives, named izumiphenazines A−C (1−3), and the known phenazine-1,6-dicarboxylic acid (4) were isolated from Streptomyces sp. IFM 11204. The structures of compounds elucidated by means spectroscopic methods including UV, IR, HRESIMS, 1D 2D NMR. Compounds 1−3 evaluated for their activity in overcoming TRAIL (TNF-related apoptosis-inducing ligand) resistance human gastric adenocarcinoma cells. 2 (30 μM) 3 (20 combination with showed synergistic sensitizing TRAIL-resistant AGS

To isolate and evaluate the cytotoxic activity of different actinomycetes species isolated from Red Sea coast in Sharm el-Sheikh, Egypt. Forty strains were sediments seawater samples collected Actinomycetes recognized by morphological microscopic examinations. Cell viability cytotoxicity induced crude extracts on breast cancer cell lines MDA-MB-231 assessed using methylene blue assay. The with promising identified sequencing amplifying 16S rRNA genes. antibacterial activities performed...

AbstractThe mitigation influence of N1-(4-(dimethylamino)benzylidene)-N2-(2-((4-(dimethylamino)benzylidene)amino)ethyl)ethane1,2-diamine, (DBDB) against the corrosion carbon steel and H2 production in 1.0 M HCl solution was studied. The experimental methods mass loss, gasometry, potentiodynamic polarization, PDP, electrochemical impedance spectroscopy, EIS, were utilized. PDP data confirmed that DBDB compound attitude is a mixed-type inhibitor. protection efficacy rises with increasing added...

Large language models have high compute, latency, and memory requirements. While specialized accelerators such as GPUs TPUs typically run these workloads, CPUs are more widely available consume less energy. Accelerating LLMs with enables broader AI access at a lower cost power consumption. This acceleration potential for is especially relevant during the memory-bound decoding stage of LLM inference, which processes one token time becoming increasingly utilized reasoning models. We utilize...

<title>Abstract</title> Artificial intelligence allows improvements in renewable energy systems by increasing efficiency while enhancing reliability and reducing costs. Renewable forecasting receives substantial improvement applying deep learning methods as one of its promising approaches. The research utilizes QTM with NiOA optimization for achieving maximum performance. functions through critical processes when models high accuracy large complex datasets selecting the most appropriate...

Fish pathogens causing disease outbreaks represent a major threat to aquaculture industry and food security. The aim of the presented study is develop safe effective bioactive agents against two bacterial isolates: Aeromonas hydrophila Pseudomonas fluorescens. We employed broth microdilution method investigate antibacterial effect biosynthesized silver nanoparticles (AgNPs); rutin, natural flavonoid extracted from Ruta graveneoles; heliomycin, secondary metabolite produced by marine...

Biogenic copper nanoparticles (Cu NPs) were synthesized using the aqueous crude extract of mangrove leaves, Avicennia marina (CE). GC-MS metabolite profiling CE showed that their carbohydrates are mainly composed D-mannose (29.21%), D-fructose, (18.51%), L-sorbose (12.91%), D-galactose (5.47%) and D-Talose (5.21%). Ultra-fine 11.60 ±4.65 nm comprising Cu2O Cu(OH)2 species obtained with a carbohydrate phenolic content 35.6±3.2% 3.13±0.05 mgGA/g, respectively. The impact biogenic Cu NPs on...

The reaction of 2-(1-(2-(2-(4-methoxybenzylidene)hydrazinyl)-4-methylthiazol-5-yl)ethylidene)hydrazinecarbothioamide with a range hydrazonoyl chlorides and α-halo-compounds yielded three new series thiazole derivatives. Chemical physical techniques were used to analyze all newly prepared derivatives (1H-NMR, 13C-NMR, FT-IR mass spectrometry). potential antimicrobial anticancer properties the synthesized investigated using various in vitro biological experiments. Most compounds tested...

We aimed to investigate the potential anticonvulsant effect of green synthetized selenium nanoparticles (SeNPs) using Syzygium aromaticum extract (SAE) (SAE-SeNPs) against epileptic seizures and cortical damage induced by pentylenetetrazole (PTZ) injection in rats its mechanism. A total 84 were divided into six groups; control, PTZ-exposed group, SAE + PTZ-treated sodium selenite (Na2SeO3) SAE-SeNPs diazepam group. significantly increase (p &lt; 0.05) latency time reduce both seizure...

4-Acetylpyridine

Expression of the steffimycin gene cluster in Steptomyces albus combination with plasmids directing biosynthesis different neutral and branched-chain deoxyhexoses led to identification twelve new glycosylated derivatives degrees decoration tetracyclic core. These experiments demonstrate flexibility L-rhamnosyltransferase StfG for recognition a variety D- L-deoxyhexoses, harboring deoxygenation as 2-deoxyhexoses, 2,6-deoxyhexoses, 2,3,6-deoxyhexoses, their attachment...