- Building Energy and Comfort Optimization
- Esophageal and GI Pathology
- Gallbladder and Bile Duct Disorders
- Impact of Light on Environment and Health
- Thermal Radiation and Cooling Technologies
- solar cell performance optimization
- Solar Thermal and Photovoltaic Systems
- Urban Heat Island Mitigation
- Infection Control and Ventilation
- Optical Wireless Communication Technologies
- Bariatric Surgery and Outcomes
- Bladder and Urothelial Cancer Treatments
- Tuberculosis Research and Epidemiology
- Fault Detection and Control Systems
- Infectious Aortic and Vascular Conditions
- Diverse Academic Research Analysis
- Actinomycetales infections and treatment
- Diagnosis and treatment of tuberculosis
- Aortic aneurysm repair treatments
- Light effects on plants
- Minimally Invasive Surgical Techniques
- Intestinal and Peritoneal Adhesions
- Gastrointestinal Bleeding Diagnosis and Treatment
- Multicomponent Synthesis of Heterocycles
- Mycobacterium research and diagnosis
Central Scientific Instruments Organisation
2021-2024
Academy of Scientific and Innovative Research
2021-2024
Geisinger Lewistown Hospital
2021
Geisinger Medical Center
2019-2020
Christian Medical College
2016
Christian Medical College & Hospital
2016
Pfizer (United States)
2010
The Royal Free Hospital
2006
University College London
2006
Vardhman Mahavir Medical College & Safdarjung Hospital
2005
The oxazolidinone PNU-100480 is superior to linezolid against experimental murine tuberculosis. Two metabolites contribute but do not fully account for its superiority. This study examined the safety, tolerability, pharmacokinetics, and mycobactericidal activity of single ascending doses PNU-100480.Nineteen healthy volunteers received 2 escalating oral (35-1500 mg) or placebo. Eight subjects 4 daily 300 mg linezolid. Drug concentrations bactericidal Mycobacterium tuberculosis in whole-blood...
Endoscopic ultrasound-directed transgastric endoscopic retrograde cholangiopancreatography (ERCP; EDGE) is an alternative to enteroscopy- and laparoscopy-assisted ERCP in patients with Roux-en-Y gastric bypass anatomy. Although short-term results are promising, the long-term outcomes not known. The aims of this study were: (1) determine rates adverse events after EDGE, a focus on persistent gastrogastric or jejunogastric fistula; (2) identify predictors (3) assess closure when fistula...
After the outbreak of COVID-19 pandemic, a rise in demand has occurred for efficient designs disinfection systems that utilize ultraviolet-C (UVC) radiation to inactivate airborne microorganisms effectively. This paper proposes what we believe be novel standalone system inactivating Mycobacterium tuberculosis (which requires higher dosage value than SARS-CoV-2) from medium size room 12.5ft×12.5ft×9ft. The structure consists UVC source at center and spiral pathway guiding air around source,...
In this paper, the mean-wavelength-based Fresnel lens was designed by merging modified edge ray principle and idea of superposition. The bottom-to-top approach optimizes design individual prisms according to predetermined plastic optical fiber (POF) bundle size. simulated efficiency collector for sun's visible spectrum (380-740 nm) light is 82.93% with a uniformity ratio 0.434. Based on collector, daylighting system can deliver 199.38 lumens via 10 m long POF an 23.78%. thermal analysis...
A recent breakout of the COVID-19 pandemic inspired researchers to find ideal solutions for removing SARS-CoV-2 from indoor air. In-duct ultraviolet germicidal irradiation was employed in rooms with heating, ventilation, and air conditioning (HVAC) systems stop spread COVID-19. The current investigation introduces Bunimovich stadium-inspired flow channels inside square-shaped duct. impact channel shape on light distribution is studied compared traditional rectangular-shaped core a square δ γ...
A carefully designed daylight collector for a tubular skylight is necessary to serve the occupants' illumination needs under dynamic trajectory of sun. This work simulated an improved configuration passive comprising parabolic and conical reflectors in modeled room using lighting software tool TracePro. Results indicated that performance proposed design was significantly enhanced low altitude sun comparison with conventional skylights (with revolved cylindrical reflectors) [Light. Res....
Daylighting using natural illumination system (NILS) is gaining popularity due to transition the renewable and non-conventional energy resources. In proposed work, optomechanical design, numerical analysis, experimentation integration of a modular Fresnel lens for NILS effectively harness sunlight discussed. The integrated design delivers uniform light at receiving area daylight transportation system. This combination linear lenses designed offer moderate concentration ratio avoid hot spots....
The paper presents the design of a Customised Homocentric Fresnel Collector (CHFC) based on principle superposition and longest wavelength visible spectrum. A bottom-to-top approach is proposed that uses an individually designed homocentric prism light at 740 nm. CHFC follows uniform height method with varying pitch. An area focus achieved plastic optical fibre (POF) bundle inlet without employing any secondary element. achieves distribution concentrated spectrum radiation from Sun...
Port site metastasis is being increasingly reported as a complication following laparoscopic surgery for malignant disorders. Various factors have been to be responsible and most are associated with either high intra-peritoneal pressure due pneumoperitoneum or the ‘chimney effect’ sudden decompression of abdomen. Direct implantation offending cells at raw surface port has also implicated use retrieval bags therefore recommended. We report on rare case seeding tuberculosis in 65-year-old...
INTRODUCTION: The rising obesity epidemic in the US has led to an increase bariatric surgeries, and Roux-en-Y gastric bypass (RYGB) is a common option. These patients are at higher risk for gallstone disease, but resulting altered anatomy presents unique challenges accessing bile duct. Lap-assisted ERCP (LAERCP) most modality biliary access this setting leads high resource utilization morbidity. EUS-directed trans-gastric (EDGE), emerging as new alternative. We present comparison between...
The incidence of isolated iliac artery aneurysm is rare. We report a 78-year-old male with bilateral common and internal aneurysm. Computerized tomography angiogram the aorta revealed partially thrombosed aneurysms involving arteries mass effect. infrarenal abdominal tortuous ectatic. clinical presentation management are discussed.
INTRODUCTION: Actinomyces is a commensal in aero-digestive tracts which rarely causes infection. The commonest site cervicofacial region. Risk factors are low immunity and pre-existing tissue damage. Esophageal involvement rare. We report case of esophageal actinomycosis an immunocompetent patient. CASE DESCRIPTION/METHODS: A 71-year-old male presented with recurrent dysphagia. patient had multiple prior EGDs for management refractory peptic stricture due to gastrin secreting pancreatic...
INTRODUCTION: Patients are exposed to radiation during endoscopic retrograde cholangiopancreatography (ERCP) which may increase the cumulative risk of development cancer and/or other radiation-related adverse events. ERCP utilizes radiological guidance direct diagnosis and therapy biliary pancreatic pathology. There is limited data available evaluating if amount directed patient different by endoscopist-directed fluoroscopy versus when assisted radiology technician. Our aim was assess...