- Micro and Nano Robotics
- Marine Biology and Environmental Chemistry
- Molecular Communication and Nanonetworks
- Polymer Surface Interaction Studies
- Microfluidic and Bio-sensing Technologies
- Environmental Toxicology and Ecotoxicology
- Marine Ecology and Invasive Species
- Antimicrobial agents and applications
- Modular Robots and Swarm Intelligence
- Marine Bivalve and Aquaculture Studies
- Characterization and Applications of Magnetic Nanoparticles
- Advanced DC-DC Converters
- Photoreceptor and optogenetics research
- Electrohydrodynamics and Fluid Dynamics
- Advanced Materials and Mechanics
- Lipid Membrane Structure and Behavior
- Maritime Transport Emissions and Efficiency
- GaN-based semiconductor devices and materials
- Photosynthetic Processes and Mechanisms
- Ship Hydrodynamics and Maneuverability
- Marine and Offshore Engineering Studies
- Marine Sponges and Natural Products
- Synthesis of heterocyclic compounds
- Advanced biosensing and bioanalysis techniques
- Ocean Waves and Remote Sensing
Sichuan Agricultural University
2024
Ocean University of China
2015-2024
Hong Kong Polytechnic University
2023
University of Chinese Academy of Sciences
2022
Harbin Institute of Technology
2018-2020
Shenzhen Second People's Hospital
2019
Shenzhen University Health Science Center
2019
Xiamen University
2013-2018
Nanjing Tech University
2014
Materials Science & Engineering
2014
The T-1000 liquid metal terminator, which can transform and self-repair, represents a dream for decades that robots fundamentally change our daily life. Until now, some large-scale machines have been developed. However, there is no report on nanoscaled their biomedical applications. We describe here shape-transformable fusible rodlike swimming nanomachine, based the biocompatible transformable gallium. These nanomachines were prepared by pressure-filter-template technology, diameter length...
Abstract We report a near‐infrared (NIR) light‐powered Janus mesoporous silica nanomotor (JMSNM) with macrophage cell membrane (MPCM) cloaking that can actively seek cancer cells and thermomechanically percolate membrane. Upon exposure to NIR light, heat gradient across the boundary of JMSNMs is generated by photothermal effect Au half‐shells, resulting in self‐thermophoretic force propels JMSNMs. In biological medium, MPCM camouflaging not only prevent dissociative blocks from adhering but...
We report an ultrasound-driven gold-nanoshell-functionalized polymer multilayer tubular nanoswimmer that can photomechanically perforate the membrane of a cancer cell by assistance near-infrared (NIR) light. The nanoswimmers were constructed template-assisted layer-by-layer technique and subsequent functionalization Au nanoshells inside big opening. exhibit efficient controllable movement toward target cells through manipulation acoustic field. Next, with end-on attachment onto HeLa achieve...
Summary Chlamydomonas reinhardtii is a unicellular green alga. It model system for studying functions of the chloroplast, basal body and flagella. The completion genome sequence makes it possible to use reverse genetic approaches in this organism. contains set endogenous microRNAs (miRNAs) that down‐regulate their target gene expression through mRNA cleavage. Here we developed an artificial miRNA‐based strategy knock down . Using miRNA precursor as backbone, constructed two miRNAs (amiRNAs)...
Isolation of specific rare cell subtypes from whole blood is critical in cellular analysis and important basic clinical research. Traditional immunomagnetic capture suffers suboptimal sensitivity, specificity, time- cost-effectiveness. Mimicking the features octopuses, a device termed "NanoOctopus" was developed for cancer isolation blood. The consists long multimerized aptamer DNA strands, or tentacle DNA, immobilized on magnetic microparticle surfaces. Their ultrahigh sensitivity...
Abstract Swimming nanorobots performing efficient self‐propulsion in various biofluids have drawn tremendous attention over 15 years due to their application including active drug delivery, precise cell manipulation, noninvasive surgery, rapid biosensor, and mobile vivo imaging the field of biomedicine. However, there are still many challenges using swimming practice for delivery therapy, such as biocompatibility chemical fuels or externally physical fields, biodegradation synthetic...
Abstract We report a near‐infrared (NIR) light‐powered Janus mesoporous silica nanomotor (JMSNM) with macrophage cell membrane (MPCM) cloaking that can actively seek cancer cells and thermomechanically percolate membrane. Upon exposure to NIR light, heat gradient across the boundary of JMSNMs is generated by photothermal effect Au half‐shells, resulting in self‐thermophoretic force propels JMSNMs. In biological medium, MPCM camouflaging not only prevent dissociative blocks from adhering but...
An inner-motile photocatalyst film is developed by employing artificial cilia, which provides an impactful methodology for overcoming mass transfer limitation due to the microfluidic mixing capability. The photocatalytic performance significantly enhanced.
In recent years, there has been considerable push toward the biomedical applications with active particles, which have great potential to revolutionize disease diagnostics and therapy. The direct penetration of particles through cell membrane leads more efficient intracellular delivery than previously considered endocytosis processes but may cause disruption. Understanding fundamental behaviors membranes in response such extreme impacts by is crucial develop particle-based technologies...
Utilizing bottom-up controllable molecular assembly, the bio-inspired polyelectrolyte multilayer conical nanoswimmers with gold-nanoshell functionalization on different segments are presented to achieve optimal upstream propulsion performance. The experimental investigation reveals that presence of gold nanoshells big openings could not only bestow efficient directional but also minimize impact from external flow. at facilitate acoustically powered against a flow velocity up 2.00 mm s–1,...
Objective To investigate the effects of Saffloryellow (SY) on flaps with ischemiareperfusion injury (IRI) in rats and mechanism.Methods Thirty-two SD were used to establish IRI skin along superficial epgastric artery.All randomly divided into control experimental groups (n =16 each).SY injection [40 mg/(kg· d)] normal saline same volume injected abdominal cavity respectively at 1 h prior reperfusion next 6 days after operation.The survival rate,pathologic changes,levels superoxide dismutase...
Ship fouling has significant adverse effects on vessel performance and environmental sustainability. Therefore, this research study develops a bi-level programming model to simultaneously optimize cleaning equipment deployment by service providers in the upper level decisions shipping companies lower level. To address interaction within problem, is transformed into single-level formulation using big-M method. This transformation greatly simplifies complexity of computation reduces time....
In this paper, a high frequency OLED driver circuit is proposed. Without choke inductors, the profile of can be greatly reduced. Class Φ <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> inverter used to reduce voltage stress switch while maintaining soft switching characteristics. The T-type network maintains constant current output over wide load range reflected impedance remains resistive. A 48V input 150mA prototype based on GaN HEMTs...