- Advanced Photocatalysis Techniques
- Advanced biosensing and bioanalysis techniques
- Gold and Silver Nanoparticles Synthesis and Applications
- Advanced Nanomaterials in Catalysis
- Analytical chemistry methods development
- TiO2 Photocatalysis and Solar Cells
- Advanced oxidation water treatment
- Carbon and Quantum Dots Applications
- Nanocluster Synthesis and Applications
- Nanoparticle-Based Drug Delivery
- Nanoplatforms for cancer theranostics
- Electrochemical Analysis and Applications
- Luminescence Properties of Advanced Materials
- Gas Sensing Nanomaterials and Sensors
- Electrochemical sensors and biosensors
- Biosensors and Analytical Detection
- Drug Transport and Resistance Mechanisms
- Quantum Dots Synthesis And Properties
- Analytical Chemistry and Chromatography
- RNA Interference and Gene Delivery
- Environmental remediation with nanomaterials
- Bone Tissue Engineering Materials
- Pharmaceutical and Antibiotic Environmental Impacts
- Nanomaterials for catalytic reactions
- Microfluidic and Capillary Electrophoresis Applications
Cape Breton University
2016-2025
Northeast Forestry University
2024-2025
Zhengzhou University
2020-2025
Lanzhou University
2022-2025
Zhangzhou Municipal Hospital of Fujian Province
2025
Chinese Center For Disease Control and Prevention
2014-2025
Shaanxi Yulin Energy Group
2025
CHN Energy (China)
2025
Jiangsu University
2014-2024
Northeast Agricultural University
2021-2024
The attachment of thiolated DNA to gold nanoparticles (AuNPs) has enabled many landmark works in nanobiotechnology. This conjugate chemistry is typically performed using a salt-aging protocol where, the presence an excess amount DNA, NaCl gradually added increase loading over 1-2 days. To functionalize large AuNPs, surfactants need be used, which may generate difficulties for downstream biological applications. We report herein novel method pH 3.0 citrate buffer complete process few minutes....
Single-stranded DNA can be adsorbed by citrate capped gold nanoparticles (AuNPs), resulting in increased AuNP stability, which forms the basis of a number biochemical and analytical applications, but fundamental interaction this adsorption reaction remains unclear. In study, we measured kinetics, capacity, isotherms, demonstrating that process is governed electrostatic forces. The charge repulsion among strands between AuNPs reduced adding salt, reducing pH or using noncharged peptide...
Raman microscopy is a quantitative, label-free, and noninvasive optical imaging technique for studying inhomogeneous systems. However, the feebleness of scattering significantly limits use to low time resolutions primarily static samples. Recent developments in narrowband stimulated (SRS) have increased acquisition speed based label-free by few orders magnitude, at expense reduced spectroscopic information. On basis spectral focusing approach, we present fast SRS hyperspectral system using...
Stimulated Raman scattering (SRS) microscopy is a newly developed label-free chemical imaging technique that overcomes the speed limitation of confocal while avoiding nonresonant background problem coherent anti-Stokes (CARS) microscopy. Previous demonstrations have been limited to single band measurements. We present novel modulation multiplexing approach allows real-time detection multiple species using fast Fourier transform. demonstrate quantitative determination concentrations in...
Adsorption of a fluorophore-labeled DNA probe by graphene oxide (GO) produces sensor that gives fluorescence enhancement in the presence its complementary (cDNA). While many important analytical applications have been demonstrated, it remains unclear how hybridization takes place GO, hindering further rational improvement design. For first time, we report set experimental evidence to reveal new mechanism involving nonspecific displacement followed solution phase. In addition, show...
For many applications, it is desirable to stabilize colloids over a wide range of buffer conditions while still retaining surface accessibility for adsorption and reaction. Commonly used charge or steric stabilization cannot achieve this goal since the former sensitive salt latter blocks particle surface. We use depletion in presence high molecular weight polyethylene glycol (PEG) diverse nanomaterials, including gold nanoparticles (from 10 100 nm), graphene oxide, quantum dots, silica...
A PLGA nanofiber membrane supported lung-on-a-chip microdevice was developed to model the alveolar microenvironment for anti-cancer drug testing.
The photocatalytic O2 activation for pollutant removal highly depends on the controlled generation of desired reactive oxygen species (ROS). Herein, we demonstrate that robust excitonic effect BiOBr nanosheets, which is prototypical singlet (1O2) production to partially oxidize NO into a more toxic intermediate NO2, can be weakened by surface boronizing via inducing staggered band alignment from bulk and simultaneously generating vacancy (VO). destabilizes excitons facilitates their...
Amorphous nanometer alumina (nano-Al2O3) was prepared by inverse microemulsion method in the presence of aluminum sulfate octadecahydrate as source, poly(ethylene glycol) octyl-phenyl ether and cetyl trimethyl ammonium bromide emulsifiers, n-butanol co-surfactant. The optimal condition for preparing nano-Al2O3 investigated relation to effect stirring rate on morphology adsorption performance product; capacity mechanism AsO43- ion aqueous solution were explored based simulations with...
Au@Ag core−shell nanocrystals have been synthesized by using a microwave−polyol method, and their growth mechanisms studied. When HAuCl4·4H2O was reduced in ethylene glycol the presence of poly(vinylpyrrolidone) (PVP) as polymer surfactant, mixture triangular twin platelike, octahedral, multiple-twinned decahedral Au nanocrystals, having only {111} facets, prepared. Ag+ these seeds, triangular-bipyramidal, cubic, rod/wire Ag shells, {100} were overgrown, respectively. It concluded that...
The last 16 years have witnessed the landmark development of polyvalent thiolated DNA-functionalized gold nanoparticles (AuNP's) possessing striking properties within emerging field nanobiotechnology. Many novel this hybrid nanomaterial are attributed to dense DNA shell. However, question whether nonthiolated DNA-AuNP could be fabricated with a high density and similar those its counterpart has not been explored in detail. Herein, we report that by simply tuning pH mixture an ultrahigh...
In this paper, large scale hierarchically assembled NiO nanosheets have been favorably fabricated through a facile hydrothermal route. The as-prepared nanosheet assembles were characterized in detail by various analytical techniques. results showed these present the thickness of about 30 nm and surface area is 116.9 m2 g−1. These used as working electrode materials electrochemical tests, which demonstrated specific capacitance value 81.67 F g−1 at current density 0.5 A excellent long...
Abstract Imaging of nucleic acids is important for studying cellular processes such as cell division and apoptosis. A noninvasive label‐free technique attractive. Raman spectroscopy provides rich chemical information based on specific vibrational peaks. However, the signal from spontaneous scattering weak long integration times are required, which drastically limits imaging speed when used microscopy. Coherent techniques, comprising coherent anti‐Stokes (CARS) stimulated (SRS) microscopy,...
Enzyme-like metal–organic frameworks (MOFs) are currently one type of starring material in the fields artificial enzymes and analytical sensing. However, there has been little progress making use MOF structures based on catalytically active metal center with multiple valences. Herein, we report a mixed-valence Ce-MOF (Ce-BPyDC) that can exhibit both oxidase-like peroxidase-like activities. Ce-BPyDC was synthesized by facile hydrothermal method, which preserves rare coexistence Ce(III) Ce(IV)...
Biocompatible, multifunctional, stimuli responsive, and high drug loading capacity are key factors for the new generation of delivery platforms. However, it is extremely challenging to create such a platform that inherits all these advanced properties in single carrier. Herein, porous silicon nanoparticles (PSi NPs) giant liposomes assembled on microfluidic chip as an nano‐in‐micro NPs@giant liposomes), which can co‐load co‐deliver hydrophilic hydrophobic drugs combined with synthesized DNA...
Titanium dioxide (TiO2) or titania shows great promise in detoxification and drug delivery. To reach its full potential, it is important to interface TiO2 with biomolecules harness their molecular recognition function. this end, DNA attachment an topic. Previous work has mainly focused on long double-stranded single nucleotides. For biosensor development targeted delivery, more use single-stranded oligonucleotides. Herein, the interaction between fluorescently labeled oligonucleotides...