A5002178964- Adrenal and Paraganglionic Tumors
- Hormonal Regulation and Hypertension
- Adrenal Hormones and Disorders
- Parathyroid Disorders and Treatments
- Thyroid Cancer Diagnosis and Treatment
- Thyroid and Parathyroid Surgery
- Facial Rejuvenation and Surgery Techniques
- COVID-19 Clinical Research Studies
- Pituitary Gland Disorders and Treatments
- SARS-CoV-2 and COVID-19 Research
- Genetic factors in colorectal cancer
- Anesthesia and Pain Management
- Cardiac, Anesthesia and Surgical Outcomes
- Computational Drug Discovery Methods
- Long-Term Effects of COVID-19
- Cancer, Hypoxia, and Metabolism
- Craniofacial Disorders and Treatments
- Temporomandibular Joint Disorders
- Dental Implant Techniques and Outcomes
- BRCA gene mutations in cancer
- Blood Pressure and Hypertension Studies
- Spinal Hematomas and Complications
- Orthodontics and Dentofacial Orthopedics
- Apelin-related biomedical research
- Gut microbiota and health
University of Naples Federico II
2023-2025
Agostino Gemelli University Polyclinic
2020-2021
Università Cattolica del Sacro Cuore
2011-2020
Istituti di Ricovero e Cura a Carattere Scientifico
1992-2019
University of the Sacred Heart
2019
Casa Sollievo della Sofferenza
1998-1999
In addition to biochemical cure, clinical benefits after surgery for primary aldosteronism depend on the magnitude of decrease in blood pressure (BP) and use antihypertensive medications with a subsequent decreased risk cardiovascular and/or cerebrovascular morbidity drug-induced adverse effects.To evaluate change BP within an international cohort patients who recently underwent aldosteronism.A study was conducted across 16 referral medical centers Europe, United States, Canada, Australia....
The renin-angiotensin-aldosterone system (RAAS), a metabolic cascade regulating pressure and circulating blood volume, has been considered the main involved in pathogenesis of severe lung injury organs decline COVID-19 patients. angiotensin I-converting enzyme (ACE1), angiotensin-converting 2 (ACE2), angiotensinogen (AGT) receptors II receptor type 1 (AGTR1) are key factors for SARS-CoV-2 entering cells, sodium water retention with an increase pressure, promotion fibrotic inflammatory...
Laparoscopic adrenalectomy is the preferred surgical approach for adrenal resection. The simultaneous presence of obesity and subsequent liver steatosis may complicate procedure, increasing risk intra- perioperative complications. This study explores effectiveness a preoperative very low-calorie ketogenic diet in improving outcomes patients with undergoing laparoscopic adrenalectomy. A retrospective analysis was conducted on 70 from January 2021 to July 2024 at Bariatric Endocrine-Metabolic...
Maxillo-mandibular asymmetry has numerous aetiologies: congenital, traumatic, iatrogenic and post-oncologic. Patients with congenital dentofacial malformations are generally submitted to orthognathic surgery and/or additional procedures (genioplasty, alloplastic implants) satisfactory results. However, despite achieving skeletal symmetry, noticeable facial may persist.This study was performed in 45 patients (29 women 16 men) operated between December 2012 June 2014. All were affected by...
In this prospective, randomised, double-blind study, we investigated the effect of epidural anaesthesia and an antifibrinolytic agent, Aprotinin (500,000 KIU in bolus before surgery 500,000 h- 1 drip form during surgery), on intra postoperative blood loss transfusion requirements total hip arthroplasty. Sixty patients were allocated randomly to four groups (A: + general anesthesia Aprotinin, B: placebo (equal volume), C: D: placebo). Postoperative analgesia: analgesia A B, systemic with...
Abstract Background Various diagnostic tests are available to establish the primary aldosteronism (PA) diagnosis and determine disease laterality. Combined with controversies in literature, unawareness of guidelines technical demands high costs some these diagnostics, this could lead significant differences work‐up strategies worldwide. Therefore, we investigated before surgery for PA daily clinical practice within a multicenter study. Methods Patients who underwent unilateral adrenalectomy...
Abstract The important physiological and pathophysiological roles of intestinal human microbiome (HMB) in health have been emerging, owing to the access molecular biology techniques. Herein we evaluated, for first time, HMB through direct hybridization approach using n-counter flex DX technology which bypasses amplification procedure currently applied by other technologies study microbiome. To this purpose, a clinical was carried out on fecal samples, recruiting both healthy volunteers...
Abstract Atraumatic splenic rupture (ASR) is a rare clinical entity. Several underlying benign and malignant conditions have been described as leading cause. We report on case of ASR in 41-year-old man treated with laparoscopic splenectomy. Considering life-threatening condition, prompt diagnosis can be life saving.
A 68-year-old female patient with tenesmus and blood in the stool was admitted to S.G. Moscati Hospital of Taranto. Investigations revealed infiltrative mucinous colon adenocarcinoma accompanied by lymph node metastases. Following surgery adjuvant chemotherapy, computed tomography (CT) carcinoembryonic antigen screening were negative. Two years later, CT demonstrated a liver lesion. Histologic genetic analyses confirmed diagnosis metastatic colorectal cancer coexistence KRAS BRAF mutations...
The gold standard in modern surgical treatment of patients with severe maxillo-mandibular atrophy must include the aim to achieve restoration function and aesthetics immediate reconstruction oro-mandibular defects. medical records 14 who were treated a 5-year period (2010-2014) at our department maxillary mandibular atrophy, reconstructed by vascularised free fibula flap reviewed. Among former, total underwent using osteoperiosteal flap. No major complications reported. main advantage this...
Cure of hypertension after adrenalectomy for primary aldosteronism is no certainty and therefore preoperative patient counseling essential. The Primary Aldosteronism Surgical Outcome (PASO) Score a useful prediction model with an area under the curve (AUC) 0.839. PASO includes 'Target Organ Damage' (TOD) (i.e., left ventricular hypertrophy and/or microalbuminuria), which often unavailable during might limit its use in clinical practice. We hypothesized that score would still be if TOD...