Thyroid disease is considered one of the most common health disorders, which may lead to various problems. Recent studies reveal that approximately 42 million people in India face thyroid dysfunction or disorder The hormone responsible for hypothyroidism hyperthyroidism TSH (Thyroid Stimulating Hormone), T3 (Triiodothyronine, T3-RIA), FT4 (FT4, Free Thyroxine), T4 (Thyroxine), FTI (Free Thyroxine Index, FTI, T7) are significant components test performed diagnose behavior hormone. However,...

Alzheimer's disease (AD) is one of the most prevalent types dementia, which primarily affects people over age 60. In clinical practice, it a challenging task to identify AD in its early stages, and there are currently very few reliable diagnostic systems available for identification. Additionally, studies medications have high risk failure, currently, no confirmed cure. There various stages AD: mild demented, mild, moderate. It these due demented case worsens results complete health loss...

Skin diseases are commonly identified problems all over the world. There various kinds of skin diseases, such as cancer, vulgaris, ichthyosis, and eczema. Vitiligo is one that can occur in any area body, including inner part mouth. This type have immense negative impacts on human involving memory issues, hypertension, mental health problems. Conventionally, dermatologists use biopsy, blood tests, patch testing to identify presence provide medications patients. However, these treatments don't...

Skin cancer is the most dangerous and lethal that affects millions of people each year. The accurate identification skin cancers can not be accomplished without expert dermatologists. However, specific research studies WHO in Canada, US Australia, show year 1960s to 1980s, cases has noted more than two times increased comparison with previous years. its early stage an expensive difficult task because it doesn't cause too much bad initial phase. Whereas, growth requires biopsy many other...

Oral cancer is a common form of in India, particularly among men. About 95% are squamous cell carcinomas. Tobacco along with alcohol regarded as the major risk factors.(i) To determine associations oral carcinoma (OSCC) respect to gender, age group, socioeconomic status and habits; (ii) observe distribution affected anatomical sites clinico-pathological profile OSCC patients.This an unmatched case-control study during period January 2012 December 2013. Total 471 confirmed patients 556...

It is evident from the research in recent years that short sleep has been found as a risk factor for obesity. However, we still need enough evidence this field. Therefore, explored directionality of association between duration and quality with body mass index (BMI).The aim study to evaluate BMI among young adults.(a) To assess BMI. (b) BMI.In cross-sectional study, 88 individuals selected King George's Medical University were taken participants. Majority patients males (67%). There 29...

Background/Aims Health-impairing lifestyle during adolescence is an important marker for poor health. An unhealthy may lead to physical and psychological problems in adulthood. Most of the prior researches were done among adult population. Therefore, we assessed chronotype pattern correlation health-impairing lifestyles with sleep quality according circadian typology medical students. Material Methods In this cross-sectional research, a total 203 subjects enrolled. All divided into definite...

Background: Premenstrual syndrome (PMS) is a disorder affecting large number of population in terms their physical and psychological well-being. A college drop outs are because PMS. Aims Objectives: The objective this study was to assess the prevalence presence different symptoms PMS premenstrual dysphoric (PMDD) among medical girls its effect on social academic life. Materials Methods: This conducted 1st, 2nd, 3rd year MBBS student by providing them questionnaire regarding PMDD...

It is well established that obesity a major health risk in diabetes and associated diseases. Epigenetic changes, specially DNA methylation, play an important role regulation of adipokines. The objective the present study was to evaluate methylation status at promoter region leptin gene obese individuals its association with metabolic factors.The included (n=100) non-obese (n=75) aged 25-45 years, measured their physical, biochemical parameters (glucose, insulin, lipid profiles) leptin,...

Diurnal variability in airways has most commonly been reported using peak expiratory flow (PEF) and forced volume one second (FEV1). Characteristics of small, mid large caliber are expected to be different but have not studied.The aim the study was assess diurnal variation small FEF25, FEF50, FEF75 FEF25-75 along with PEF FEV1 healthy subjects.Spirometry performed 161 subjects twice a day. FEF75, FEF25-75, were determined compared.It revealed that all parameters exhibit significant...

Background: Obesity is the leading public health crisis of our time. A chronic imbalance between energy intake and expenditure will eventually lead to obesity. Several micronutrients are found be involved in development Magnesium have some role Aims Objective: Objective this study was evaluate correlation serum magnesium with different parameters obesity such as body weight, basal metabolic rate, waist circumference (WC), waist-hip ratio on basis hypothesis that subjects hypomagnesemia...

Curcumin, traditionally utilized as a flavouring zest part of Indian cooking, has been accounted to decrease the proliferation potential most cancer cells. Apoptosis is mechanism by which anticancer therapies including chemotherapy, radiation and antihormonal therapy kill tumour/cancer Novel agents that may sensitize drug-resistant tumour cells for induction apoptosis customary treatments could lead regression improved prognosis refractory disease. Indeed, chemotherapeutic have shown killing...

The role of resistin in insulin sensitivity and metabolic syndrome has been controversial until now. Increased plasma/serum levels are associated with resistance. aim this study was to investigate the relationship between serum markers males.A total 386 male volunteers were enrolled a case-control study. All analyzed confirm following guidelines National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) 2001. Of volunteers, 192 categorized as cases syndrome, whereas 194...

Context Orexin is a recently identified neuropeptide hormone. Objectives Acute and long-term post-bariatric changes in relationship to post-operative metabolic outcomes. Design Participants Men women undergoing biliopancreatic diversion with duodenal switch bariatric surgery (n = 76, BMI≥35 kg/m2) were evaluated for body composition plasma parameters at baseline, acutely (1 5 days) (6 12 months) post-surgery. Setting University Hospital Centre, Canada. Interventions Main Outcome Measures...

Studies have shown that alterations in the sleep cycle can predispose to several disorders. Most of previous studies were done on adults. Hence, aim study was see effect circadian disruption health adolescent population.In this cross-sectional study, 203 subjects enrolled. Study divided into three groups: definite evening chronotype, intermediate and morning chronotype. Sleep quality measured by Pittsburgh Quality Index (PSQI). Daytime sleepiness chronotype Epworth Sleepiness Score...

The present investigations were aimed to identify the possible association between genetic polymorphism in interleukin-6 (IL-6) G-174C gene, which confers susceptibility metabolic syndrome, and serum level of resistin North Indian women. study population comprised 370 unrelated women (192 having abdominal obesity 178 controls). Polymorphism genotype (CC+GC) IL-6 gene was determined using a combination polymerase chain reaction (PCR) sequence-specific primer with restriction fragment length...

The central component of the complement system, C3, is associated with obesity, metabolic syndrome and cardiovascular disease however underlying reasons are unknown. In present study we evaluated gene expression cleavage product C3a/C3adesArg its cognate receptor C3aR in subcutaneous omental adipose tissue women.Women (n = 140, 21-69 years, BMI 19.5-79 kg/m2) were for anthropometric blood parameters, expression.Subjects separated into groups 34-36) according to obesity: normal/overweight...