A5062389575- Medical Imaging Techniques and Applications
- Radiation Detection and Scintillator Technologies
- Atomic and Subatomic Physics Research
- Nuclear Physics and Applications
- Advanced X-ray and CT Imaging
- Epilepsy research and treatment
- Particle Detector Development and Performance
- Neuroscience and Neuropharmacology Research
- Radiation Therapy and Dosimetry
- Photonic and Optical Devices
- Digital Radiography and Breast Imaging
- Radiomics and Machine Learning in Medical Imaging
- Advanced NMR Techniques and Applications
- Silicon Nanostructures and Photoluminescence
- Radiopharmaceutical Chemistry and Applications
- Photorefractive and Nonlinear Optics
- Advanced Radiotherapy Techniques
Ghent University
2019-2021
NEMA characterization of PET systems is generally based on 18F because it the most relevant radioisotope for clinical use PET. has a half-life 109.7 min and decays into stable 18O via β+ emission with probability over 96% maximum positron energy 0.633 MeV. Other commercially available radioisotopes, such as 82Rb 68Ga have more complex decay schemes variety prompt gammas, which can directly fall window induce false coincidence detections by scanner.Aim this work was three-fold: (A) Develop...
Abstract GABAA receptors containing the α5 subunit mediate tonic inhibition and are widely expressed in limbic system. In animals, activation of α5-containing impairs hippocampus-dependent memory. Temporal lobe epilepsy is associated with memory impairments related to neuron loss other changes. The less selective PET ligand [11C]flumazenil has revealed reductions receptors. hypothesis that receptor alterations present temporal could contribute impaired untested. We compared availability...
Recently, the first TB-PET scanner was unveiled and initial results were nevertheless impressive. However, cost of a is prohibiting for many institutions around globe. Therefore here we investigate reduction strategy incorporating flexible detector arrangement. The proposed arrangement increases axial field view while keeping overall at lower levels. We propose ring splitting, which separates full rings, compact PET scanner, to an expanded with rings having only even or odd numbered...
The vast majority of PET detectors in the field today are based on pixelated scintillators. Yet, resolution this type detector is limited by pixel size. To overcome limitation, one can use monolithic detectors. However, architecture demands specific and high-speed readout photodetector array. A commonly used approach to integrate current pulses generated every but such circuitry quickly becomes bulky, power consuming expensive. objective work investigate a novel event positioning scheme for...