A5046218619- Pneumonia and Respiratory Infections
- Colorectal Cancer Screening and Detection
- Gastric Cancer Management and Outcomes
- Prostate Cancer Treatment and Research
- Head and Neck Cancer Studies
- Prostate Cancer Diagnosis and Treatment
- Management of metastatic bone disease
- Advanced Radiotherapy Techniques
- Emergency and Acute Care Studies
- Radiomics and Machine Learning in Medical Imaging
- Nutrition and Health in Aging
- Reproductive Health and Technologies
- Liver Disease and Transplantation
- Genetic factors in colorectal cancer
- Assisted Reproductive Technology and Twin Pregnancy
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Organ Transplantation Techniques and Outcomes
- Medical Imaging Techniques and Applications
- Poisoning and overdose treatments
- Cancer Diagnosis and Treatment
- Sepsis Diagnosis and Treatment
- Asthma and respiratory diseases
- Prenatal Screening and Diagnostics
- Pneumocystis jirovecii pneumonia detection and treatment
- Respiratory viral infections research
BioCruces Health research Institute
2015-2022
Hospital de Cruces
2012-2022
Osakidetza
2016-2022
Government of the Republic of Korea
2020
University of the Basque Country
2012-2016
<h3>Background</h3> While several studies have reported a link between the presence of gout and adverse cardiovascular (CV) events in general population, none has addressed question whether mortality risk patients with is influenced by disease severity. <h3>Methods</h3> We applied survival analysis methodology to prospectively collected data on clinical radiographic measures severity specialty clinic based cohort 706 (1992–2008). Standardised ratios (SMR) were calculated assess magnitude...
In chronic obstructive pulmonary disease (COPD), the benefits of rehabilitation (PR) tend to wane over time. Whether maintenance techniques may help sustain achieved after completion initial PR program remains controversial.To determine whether a long-term (3-yr) preserves short-term effects on outcomes in patients with COPD.This was multicenter prospective randomized trial including 143 moderate-severe COPD, 3 years following an 8-week outpatient program. Patients were intervention group...
Background and Objective Identifying international differences in the epidemiology of acute poisonings children may help improving prevention. We sought to evaluate epidemiological presenting emergency departments (EDs) from 8 different global regions. Methods This was an multicenter cross-sectional prospective study including younger than 18 years with 105 EDs 20 countries conducted. Data collection started at each ED between January September 2013, continued for 1 year. Results During...
Abstract In pseudohypoparathyroidism (PHP), PTH resistance results from impairment of signal transduction G protein–coupled receptors caused by a deficiency the Gsα-cAMP signaling cascade due to diminished Gsα activity in maternally imprinted tissues. PHP-Ia, inactivating mutations GNAS gene lead haploinsufficiency some tissues with biallelic expression, so addition PHP, Albright's hereditary osteodystrophy (AHO) is also present. PHP-Ib, methylation defects at locus, was thought be limited...
Recent advances in genetics and epigenetics have revealed an overlap between molecular clinical features of pseudohypoparathyroidism (PHP) subtypes, broadening the previous spectrum PHP genotype-phenotype correlations indicating limitations current classification disease.The aim study was to screen patients with diagnoses type I or pseudo-PHP for underlying defects explore possible findings features.We investigated GNAS locus at level 72 affected (46 women 26 men) from 56 nonrelated...
Purpose: To describe the clinical characteristics and to assess visual prognosis of patients with syphilis-associated uveitis in northern Spain.Methods: Retrospective review records eight general referral centers.Results: Since year 2000, 50 have been diagnosed: 31 men 19 women; median age was 41 (19–76) years. A total 34% were co-infected HIV 24% presented systemic manifestations syphilis. Median initial acuity vision at last visit 93 affected eyes 20/50 (20/20–20/2000) 20/22...
with Arana-Arri E, who also wrote the discussion Gutierrez-Ibarluzea I and statistical methodology in coordination Martínez-Indart L, analyzed data drew up results; Idigoras Bilbao registered every cancer case reviewed all items related to quality control; Bujanda L clinical features contrasted against published articles; offered feedback on
The population-based Basque Colorectal Cancer (CRC) Screening Programme started in 2009 with a biennial immunochemical quantitative test (FIT) and colonoscopy under sedation positive cases. population target of 586,700 residents was from 50 to 69 years old the total coverage reached at beginning 2014. aim our study determine possible scenarios terms incidence, mortality reduction Life-years-Lost (L-y-L) medium long term CRC. Invitations were sent out by 2014, combined organizational...
This study aimed to assess the association between pediatric assessment triangle (PAT) findings during triage and markers of severity in a emergency department (PED).During period, patients arriving PED were classified by trained nurses with Pediatric Canadian Triage Acuity Scale using computer system, from which data obtained analyzed retrospectively. The primary outcome measure was percentage children hospitalized related PAT findings. secondary measures admission intensive care unit (%),...
Abstract Aims To assess the prevalence of diabetes mellitus and impaired glucose metabolism in Basque Country their relationship with cardiovascular risk factors. Methods A population‐based, cross‐sectional, cluster sampling design study was carried out an adult (≥18 years) population. total 847 participants completed a questionnaire on personal family medical history lifestyle. Anthropometric variables blood pressure were measured biochemical analysis oral tolerance test (75 g) also...
Malnutrition is very common in patients when admitted to the hospital. The aim of present study was: a) determine prevalence malnutrition at admission a tertiary care hospital and identify risk factors for malnutrition, b) test sensitivity specificity different screening tests compared subjective global assessment (SGA).We conducted prospective 24h order assess 537 adult subjects (56.4% males, mean age 61.3±17.7 years) using 4 tools: mininutritional short form (MNA-SF), nutritional 2002...
Objective: To identify types of childhood poisoning exposures leading to consultation emergency departments (ED) in Spain. Methods: We carried out a multicenter prospective registry-based cohort study including children with acute poisonings presenting 55 pediatric EDs the Spanish Society Pediatric Emergency Medicine between 2008 and 2017, during previously designated certain days. Results: During period, we registered 749 803 ED presentations, which 1749 were for (0.23%). Most commonly...
We performed a quality improvement initiative to reduce unnecessary treatments for acute bronchiolitis (AB) in primary care (PC) and the referral paediatric emergency department (ED). The involved two seasons: 2016–2017 (preintervention) 2017–2018 (postintervention). distributed an evidence-based protocol, informative posters badges with slogan ‘Bronchiolitis, less is more’. also held interactive sessions, paediatricians received weekly reports on bronchodilator prescription. main outcome...
To evaluate the influence on sperm parameters and in vitro fertilization (IVF) outcomes of administration 400 mg/day vitamin E for 3 months to men from infertile couples who are undergoing IVF.Double-blind, placebo-controlled, randomized study.Human reproduction unit a university hospital.A total 101 couples, 50 group 51 placebo group, IVF, among whom 64.4% cases had an abnormal spermiogram according World Health Organization (WHO) criteria.Vitamin (α-tocopherol), mg daily by mouth months,...
BACKGROUND AND OBJECTIVES: Identifying international differences in the management of acute pediatric poisonings may help improve quality care. The objective this study was to assess variation and appropriateness gastrointestinal decontamination (GID) procedures performed children adolescents who present with emergency departments. METHODS: This an international, multicenter, cross-sectional prospective including &lt;18 years poisoning exposures presenting 105 departments 20 countries...