A5046828110- Chronic Obstructive Pulmonary Disease (COPD) Research
- Respiratory Support and Mechanisms
- Asthma and respiratory diseases
- Medical research and treatments
- Cardiovascular and exercise physiology
- Smoking Behavior and Cessation
- Mobile Health and mHealth Applications
- Body Composition Measurement Techniques
- Delphi Technique in Research
- Obstructive Sleep Apnea Research
- Respiratory and Cough-Related Research
- Neonatal Respiratory Health Research
- Health and Lifestyle Studies
- Nursing Diagnosis and Documentation
- Liver Disease and Transplantation
- Inhalation and Respiratory Drug Delivery
- Organ Transplantation Techniques and Outcomes
- Tracheal and airway disorders
- Cystic Fibrosis Research Advances
- Venous Thromboembolism Diagnosis and Management
- Pleural and Pulmonary Diseases
- Cardiovascular and Diving-Related Complications
- Behavioral Health and Interventions
- Health and Medical Education
- Liver Disease Diagnosis and Treatment
Hospital Universitario Virgen del Rocío
2015-2024
Instituto de Biomedicina de Sevilla
2013-2023
Universidad de Sevilla
2016-2023
Centro de Investigación Biomédica en Red de Enfermedades Respiratorias
2014-2023
Instituto de Salud Carlos III
2012-2023
Centro de Investigación Biomédica en Red
2020
Centre for Biomedical Network Research on Rare Diseases
2019
Florida International University
2018
Pontificia Universidad Católica de Chile
2016-2017
Junta de Andalucía
2016
Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components. Dendritic cells (DCs) play a key role in the defense against viral infections, for instance plasmacytoid DCs (pDCs), have capacity to produce vast amounts of interferon-alpha (IFN-α). In COVID-19 there is deficit DC numbers and IFN-α production, which has been associated with disease severity. this work, we described that addition deficiency, several...
We determined the effect of different exercise training modalities in patients with chronic obstructive pulmonary disease, including strength (n = 17), endurance 16), and combined 14) (half half strengthening exercises). Data were compared at baseline, end 12-week exercise-training program, 12 weeks later. Improvement walking distance was only significant group. Increases submaximal capacity for group significantly higher than those observed but similar magnitude modality, which turn muscle...
In chronic obstructive pulmonary disease (COPD), the benefits of rehabilitation (PR) tend to wane over time. Whether maintenance techniques may help sustain achieved after completion initial PR program remains controversial.To determine whether a long-term (3-yr) preserves short-term effects on outcomes in patients with COPD.This was multicenter prospective randomized trial including 143 moderate-severe COPD, 3 years following an 8-week outpatient program. Patients were intervention group...
In this paper, a first approach to the design of portable device for non-contact monitoring respiratory rate by capacitive sensing is presented. The system integrated into smart vest an untethered, low-cost and comfortable breathing Chronic Obstructive Pulmonary Disease (COPD) patients during rest period between rehabilitation exercises at home. To provide extensible solution remote using sensor other devices, preliminary development e-Health platform based on Internet Medical Things (IoMT)...
The prevalence of hepatopulmonary syndrome (HPS) and its influence on survival before after liver transplantation (LT) remain controversial. Additionally, the chronology post-LT reversibility is unclear. This study prospectively analyzed 316 patients with cirrhosis who were evaluated for LT in 2002-2007; 177 underwent at a single reference hospital. HPS was defined by partial pressure arterial oxygen (PaO2 ) <70 mmHg and/or an alveolar-arterial gradient (A-a PO2 ≥20 supine position positive...
Abstract Patients with mitochondrial myopathies (MM) usually suffer from exercise intolerance due to their impaired oxidative capacity and physical deconditioning. We evaluated the effects of a 12‐week supervised randomized rehabilitation program involving endurance training in patients MM. Twenty MM were assigned or control group. For three nonconsecutive days each week, combined cycle at 70% peak work rate upper‐body weight‐lifting exercises performed 50% maximum capacity. Training...
We conducted a pilot study of the effectiveness home telehealth for patients with advanced chronic obstructive pulmonary disease treated long-term oxygen therapy. Patients were randomized into group (n = 24) and control 21) who received usual care. in measured their vital signs on weekdays performed spirometry two days per week. The data transmitted automatically to clinical call centre. After four months monitoring mean number accident emergency department visits was slightly lower than...
Smoking cessation is a persistent leading public health challenge. Mobile (mHealth) solutions are emerging to improve smoking treatments. Previous approaches have proposed supporting with tailored motivational messages. Some managed provide short-term improvements in cessation. Yet, these were either static terms of personalization or human-based nonscalable solutions. Additionally, long-term effects neither presented nor assessed combination existing psychopharmacological therapies.This...
Abstract The aim was to assess the ability of nasopharyngeal SARS-CoV-2 viral load at first patient’s hospital evaluation predict unfavorable outcomes. We conducted a prospective cohort study including 321 adult patients with confirmed COVID-19 through RT-PCR in swabs. Quantitative Synthetic RNA cycle threshold values were used calculate log 10 copies/mL. Disease severity end follow up categorized into mild, moderate, and severe. Primary endpoint composite intensive care unit (ICU) admission...