A5035264356- Chronic Disease Management Strategies
- Frailty in Older Adults
- Health Systems, Economic Evaluations, Quality of Life
- Healthcare Systems and Technology
- Palliative Care and End-of-Life Issues
- Heart Failure Treatment and Management
- Vector-borne infectious diseases
- Viral Infections and Vectors
- Ultrasound in Clinical Applications
- Nutrition and Health in Aging
- Pharmaceutical Practices and Patient Outcomes
- Mosquito-borne diseases and control
- COVID-19 Clinical Research Studies
- Intensive Care Unit Cognitive Disorders
- Long-Term Effects of COVID-19
- Nursing care and research
- Aging, Health, and Disability
- Radiology practices and education
- Healthcare cost, quality, practices
- Antibiotic Resistance in Bacteria
- COVID-19 and healthcare impacts
- Antibiotics Pharmacokinetics and Efficacy
- Medication Adherence and Compliance
- Pneumonia and Respiratory Infections
- Geriatric Care and Nursing Homes
Hospital Universitario Virgen del Rocío
2014-2025
Universidad de Sevilla
2010-2024
Hospital Universitario Virgen Macarena
2024
Instituto de Salud Carlos III
2017-2019
Spanish Clinical Research Network
2019
Centro de Investigación Biomédica en Red
2019
Andalusian Health Service
2014
Consejería de Salud y Consumo
2014
Sociedad Española de Medicina Interna
2012
Hospital Universitario de Valme
2002
Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components. Dendritic cells (DCs) play a key role in the defense against viral infections, for instance plasmacytoid DCs (pDCs), have capacity to produce vast amounts of interferon-alpha (IFN-α). In COVID-19 there is deficit DC numbers and IFN-α production, which has been associated with disease severity. this work, we described that addition deficiency, several...
The objective of Integrated Care Pathways for Airway Diseases (AIRWAYS-ICPs) is to launch a collaboration develop multi-sectoral care pathways chronic respiratory diseases in European countries and regions.AIRWAYS-ICPs has strategic relevance the Union Health Strategy will add value existing public health knowledge by: 1) proposing common framework diseases, which facilitate comparability trans-national initiatives; 2) informing cost-effective policy development, strengthening particular...
BACKGROUND The increasing incidence of osteoporotic hip fracture (HF) has raised the requirements red blood cell (RBC) transfusions, whereas this scarce resource may cause morbidity and mortality. STUDY DESIGN AND METHODS This study was a multicenter, randomized, double‐blind, clinical trial that aimed to assess efficacy ferric carboxymaltose (FCM) with or without erythropoietin (EPO) in reducing RBC transfusion perioperative period HF. Participants (patients > 65 years admitted HF...
The presence of oxidative stress, telomere shortening, and apoptosis in polypathological patients (PP) with sarcopenia frailty remains unknown.Multicentric prospective observational study order to assess stress markers (catalase, glutathione reductase (GR), total antioxidant capacity reactive oxygen species (TAC-ROS), superoxide dismutase (SOD)), absolute length (aTL), (DNA fragmentation) peripheral blood samples a hospital-based population PP. Associations these biomarkers sarcopenia,...
Lung ultrasound (LUS) allows for the detection of a series manifestations COVID-19, such as B-lines and consolidations. The objective this work was to study inter-rater reliability (IRR) when detecting signs associated with COVID-19 in LUS, well performance test longitudinal or transverse orientation. Thirty-three physicians advanced experience LUS independently evaluated videos previously acquired using ULTRACOV system on 20 patients confirmed COVID-19. For each patient, 24 3 s were (using...
Dada la creciente adopción de ecografía clínica en medicina, es fundamental estandarizar su aplicación, formación y investigación. El propósito este documento proporcionar recomendaciones consenso para responder cuestiones sobre práctica el funcionamiento las unidades clínica. Participaron 19 expertos responsables avanzadas Se utilizó un método Delphi modificado. consideraron total 137 declaraciones consenso, basadas evidencia opinión experta. Las fueron distribuidas 10 áreas. Un 99...
Fever of intermediate duration (FID), characterized by a febrile syndrome lasting from 7 to 28 days, is frequent condition in clinical practice, but its epidemiological and etiologic features are not well described. Murine typhus (MT) worldwide illness; nevertheless, our knowledge, no studies describing characteristics have been performed the south Spain. Also, significance as cause FID unknown.To determine features, characteristics, prognosis MT and, prospectively, incidence FID.Prospective...
The mortality rate of patients with cases enterococcal bacteremia is high, although it has often been related to the patients' underlying conditions rather than infection itself. To analyze attributable prognosis (assessed by its and duration hospital stay), a prospective, matched case-control study was done. All adults an episode without endocarditis were included. A control patient randomly selected for every case sex, age ward. Univariate multivariate analyses performed. total 122 pairs...
Abstract The aim was to assess the ability of nasopharyngeal SARS-CoV-2 viral load at first patient’s hospital evaluation predict unfavorable outcomes. We conducted a prospective cohort study including 321 adult patients with confirmed COVID-19 through RT-PCR in swabs. Quantitative Synthetic RNA cycle threshold values were used calculate log 10 copies/mL. Disease severity end follow up categorized into mild, moderate, and severe. Primary endpoint composite intensive care unit (ICU) admission...
The prevalence, relationships and outcomes of sarcopenia frailty in polypathological patients remain unknown. We performed a multicenter prospective observational study six hospitals order to assess clinical features, outcome associated risk factors hospital-based population patients. cohort was recruited by performing prevalence surveys every 14 days during the inclusion period (March 2012–June 2016). Sarcopenia assessed means EWGSOP criteria Fried’s criteria. Skeletal muscle mass measured...