Eduardo Márquez Martín
A5049758158- Chronic Obstructive Pulmonary Disease (COPD) Research
- Respiratory Support and Mechanisms
- Asthma and respiratory diseases
- Respiratory and Cough-Related Research
- Pleural and Pulmonary Diseases
- Delphi Technique in Research
- Tracheal and airway disorders
- Neonatal Respiratory Health Research
- Body Composition Measurement Techniques
- Inhalation and Respiratory Drug Delivery
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Obstructive Sleep Apnea Research
- Public Health and Environmental Issues
- Health and Lifestyle Studies
- Nursing Diagnosis and Documentation
- Pulmonary Hypertension Research and Treatments
- Lung Cancer Diagnosis and Treatment
- Heart Failure Treatment and Management
- Restraint-Related Deaths
- Medical Imaging and Pathology Studies
- Employment, Labor, and Gender Studies
- Social Sciences and Policies
- Organ Transplantation Techniques and Outcomes
- Neuroscience of respiration and sleep
- Smoking Behavior and Cessation
Centro de Investigación Biomédica en Red de Enfermedades Respiratorias
2014-2025
Instituto de Biomedicina de Sevilla
2016-2025
Universidad de Sevilla
2015-2025
Hospital Universitario Virgen del Rocío
2015-2024
Instituto de Salud Carlos III
2014-2024
Centro de Investigación Biomédica en Red
2023
Instituto Nacional de Enfermedades Respiratorias
2015-2019
Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública
2018
Universidad de León
2018
Canadian Respiratory Research Network
2016
Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components. Dendritic cells (DCs) play a key role in the defense against viral infections, for instance plasmacytoid DCs (pDCs), have capacity to produce vast amounts of interferon-alpha (IFN-α). In COVID-19 there is deficit DC numbers and IFN-α production, which has been associated with disease severity. this work, we described that addition deficiency, several...
In this paper, a first approach to the design of portable device for non-contact monitoring respiratory rate by capacitive sensing is presented. The system integrated into smart vest an untethered, low-cost and comfortable breathing Chronic Obstructive Pulmonary Disease (COPD) patients during rest period between rehabilitation exercises at home. To provide extensible solution remote using sensor other devices, preliminary development e-Health platform based on Internet Medical Things (IoMT)...
<h3>Importance</h3> Active search for pulmonary embolism (PE) may improve outcomes in patients hospitalized exacerbations of chronic obstructive disease (COPD). <h3>Objective</h3> To compare usual care plus an active strategy diagnosing PE with alone COPD exacerbation. <h3>Design, Setting, and Participants</h3> Randomized clinical trial conducted across 18 hospitals Spain. A total 746 were randomized from September 2014 to July 2020 (final follow-up was November 2020). <h3>Interventions</h3>...
Background Not all hypercapnic COPD patients benefit from home noninvasive ventilation (NIV), and mechanisms through which NIV improves clinical outcomes remain uncertain. We aimed to identify “responders” NIV, denoted by a beneficial effect of on arterial partial pressure carbon dioxide ( P aCO 2 ), health-related quality life (HRQoL) survival, investigated whether achieves its an improved . Methods used individual patient data previous published trials collated for systematic review....
Chronic obstructive pulmonary disease (COPD) represents one of the most frequent causes hospital readmissions and in-hospital mortality. One in five patients requires readmission within 30 days discharge following an admission for exacerbation. These ‘early readmissions’ increase morbidity mortality, as often do not recover their baseline lung function. The identification factors associated with increased risk has been a major focus research recent years. Studies describe patient-related...
Abstract The aim was to assess the ability of nasopharyngeal SARS-CoV-2 viral load at first patient’s hospital evaluation predict unfavorable outcomes. We conducted a prospective cohort study including 321 adult patients with confirmed COVID-19 through RT-PCR in swabs. Quantitative Synthetic RNA cycle threshold values were used calculate log 10 copies/mL. Disease severity end follow up categorized into mild, moderate, and severe. Primary endpoint composite intensive care unit (ICU) admission...
Tranexamic acid (TA) is a synthetic antifibrinolytic substance used for short-term control of bleeding. However, pulmonary bleeding with endobronchial administration TA in more than 2 cases has not been attempted earlier.We tested the feasibility controlling bleeding.This was 2-year prospective observational trial consecutive patients presenting hemoptysis to our bronchoscopy unit. Patients were initially treated according recommendations Spanish National Guidelines using ice-cold saline and...
The identification of new less invasive biomarkers is necessary to improve the detection and prognostic outcome respiratory pathological processes. measurement miRNA expression through techniques such as plasma serum have been suggested analysis several lung malignancies including cancer. These studies are assuming a common deregulated both in blood tissue. present study aimed obtain representative signatures bronchoalveolar cell fraction that could serve biomarker diseases. Ten patients...
Las Terapias Respiratorias a Domicilio (TRD) engloban tratamientos variados para pacientes con enfermedades respiratorias crónicas, administrados en casa durante periodos extensos. Empresas Prestadoras de Servicios TRD (EPTRD) colaboran recursos hospitalarios atender siendo socios estratégicos. La contratación el sistema salud público implica concursos donde las EPTRD presentan ofertas técnicas y económicas. El objetivo del presente documento es ofrecer una base técnica que sirva ayuda los...
Enzyme-linked immunosorbent assay (ELISA), indirect immunofluorescent-antibody (IFA), and Western immunoblot were used to test serum samples from 128 dogs for the presence of antibody Borrelia burgdorferi. Sera included 72 suspected having Lyme disease, 32 residing in areas which disease was not considered endemic, 24 with clinical serologic evidence immune-mediated (n = 10), Rocky Mountain spotted fever 5), or leptospirosis 9). Results immunoblotting as standard against performances ELISA...
The identification of new less invasive biomarkers is necessary to improve the detection and prognostic outcome respiratory pathological processes. measurement miRNA expression through techniques such as plasma serum have been suggested analysis several lung malignancies including cancer. These studies are assuming a common deregulated both in blood tissue. present study aimed obtain representative signatures bronchoalveolar cell fraction that could serve biomarker diseases. Ten patients...
Aim: Serum ICAM-1 (sICAM-1) is known to be a smoking-associated inflammatory marker, but data in chronic obstructive pulmonary disease (COPD) are lacking. Patients & methods: A total of 142 COPD cases (48 active smokers) and 55 controls (41 were consecutively enrolled this cross-sectional study. The peripheral blood concentrations sICAM-1, IL-8 (CXCL8), CRP serum amyloid (SAA) determined by ELISA. Results: SAA (log-scale) elevated the patients with compared control subjects (p = 0.005 for p...
Second-generation tau tracers for positron emission tomography (PET) show high affinity paired helical filaments deposits characteristic of Alzheimer´s disease and low off-target binding. Differences in their chemical structure though may lead to variations regional uptake signal. In this work, we aimed compare the in-vivo [18F]PI-2620 [18F]RO948 early stages AD continuum. Data from TAU-PET FACEHBI clinical trial (EUDRA-CT 2021–000473-83) were analyzed. All participants non-demented...
Objectives. A detailed understanding of the intricate relationships between different acute phase reactants (APRs) in chronic obstructive pulmonary disease (COPD) can shed new light on its clinical course. In this case-control study, we sought to identify interaction networks a number plasma APRs COPD, with special focus their association severity. Methods. COPD cases and healthy smoking controls (3:1 ratio) were recruited our outpatient clinic. Cardiopulmonary exercise testing was used rule...