Christopher F. Murphy

ORCID: 0000-0002-6480-859X
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About
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Research Areas
  • Functional Brain Connectivity Studies
  • Dementia and Cognitive Impairment Research
  • Advanced Neuroimaging Techniques and Applications
  • Advanced MRI Techniques and Applications
  • Neural and Behavioral Psychology Studies
  • Schizophrenia research and treatment
  • Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Mental Health Research Topics
  • Intimate Partner and Family Violence
  • Treatment of Major Depression
  • Bipolar Disorder and Treatment
  • Neural dynamics and brain function
  • Memory and Neural Mechanisms
  • Alzheimer's disease research and treatments
  • Autism Spectrum Disorder Research
  • Psychosomatic Disorders and Their Treatments
  • Healthcare Decision-Making and Restraints
  • Neuroscience and Music Perception
  • Neurogenesis and neuroplasticity mechanisms
  • Pain Management and Placebo Effect
  • Family Caregiving in Mental Illness
  • Nerve injury and regeneration
  • Cardiac Health and Mental Health
  • Diet and metabolism studies
  • Mental Health Treatment and Access

Idaho Department of Health and Welfare
2023

Wexford General Hospital
2023

Murphy Oil Corporation (United States)
2002-2018

Cornell University
2004-2016

University of Arizona
2015

Whitney Museum of American Art
2006-2007

University of Maryland, Baltimore
2003

Moorfields Eye Hospital NHS Foundation Trust
2002

Institute of Sociology
2002

Washington University in St. Louis
1997

A survey of attitudes to mental illness was conducted in a quota sample about 2000 subjects Malvern and Bromsgrove. Factor analysis showed three main components – benevolence, authoritarianism, fear the mentally ill. Residents Bromsgrove, which is served by traditional hospital, were slightly more tolerant than those living Malvern, has community-based service, seen closure two hospitals its vicinity during last 10 years. The demographic determinants tolerance are age, education, occupation,...

10.1192/bjp.162.1.93 article EN The British Journal of Psychiatry 1993-01-01

Objective: White matter abnormalities may interfere with limbic cortical balance and lead to chronic depressive syndromes. The authors used diffusion tensor imaging test the hypothesis that depressed elders who fail achieve remission have microstructural white in cortico-striato-limbic networks implicated geriatric depression. Method: subjects were nondemented individuals nonpsychotic major After a 2-week placebo period, those had Hamilton Depression Rating Scale (HAM-D) score of 18 or...

10.1176/appi.ajp.2007.07050744 article EN American Journal of Psychiatry 2008-01-03

This study tested the hypothesis that microstructural abnormalities in white matter areas of brain containing frontostriatal tracts are associated with a low rate remission geriatric depression.Thirteen older patients major depression received open, but controlled, treatment citalopram at target daily dose 40 mg for 12 weeks. Diffusion tensor imaging was used to determine fractional anisotropy preselected regions.Survival analysis Cox's proportional hazards model revealed lower right and...

10.1176/appi.ajp.159.11.1929 article EN American Journal of Psychiatry 2002-10-31

To assess the reliability and stability of a standardized road test for healthy aging people those with dementia Alzheimer type (DAT).A prospective study involving patients DAT age-matched controls in which subjects' driving performance was evaluated by several raters an initial follow-up test.Urban medical school urban highways streets.A convenience sample 58 controls, 36 subjects very mild DAT, 29 DAT.Analysis ability (2 [3%] failed test), (7 [19%] failed), (12 [41%] failed) disclosed...

10.1001/archneur.1997.00550180029008 article EN Archives of Neurology 1997-06-01

The effect of hyperglycemia on hormone levels, metabolite and memory performance was examined in 22 subjects with very mild probable dementia the Alzheimer type (DAT) 12 normal elderly adults. Subjects were tested 3 plasma glucose conditions (fasting baseline, 175 mg/dl, 225 mg/dl) at initial 18-month follow-up sessions. Initially, adults DAT showed facilitation elevations insulin 225-mg/dl condition relative to baseline. At follow-up, patients whose had progressed significant decreases...

10.1037//0735-7044.107.6.926 article EN Behavioral Neuroscience 1993-01-01

Complex tests of declarative memory, working procedural learning, and response generation inhibition were administered to 27 younger adults (M = 20.8 years) 32 older 68.5 following ingestion saccharin (23.7 mg) or glucose (50 g). The effects administration examined along three dimensions: age, sex, glucoregulatory response, defined as the degree which blood levels returned baseline administration. Glucose significantly enhanced performance on memory measure paragraph recall for males whose...

10.3758/bf03327086 article EN Psychobiology 1994-06-01

Abstract Background Structural abnormalities of the anterior cingulate cortex (ACC) may interfere with interaction cortical and limbic networks involved in emotional regulation contribute to chronic depressive syndromes elderly. This study examined relationship regional volumes treatment remission elderly depressed patients. We hypothesized that patients who failed remit during a 12‐week controlled trial escitalopram would exhibit smaller gray matter than remitted. Methods The participants...

10.1002/gps.2290 article EN International Journal of Geriatric Psychiatry 2009-06-23

To determine the range of biometry prediction error postoperative refraction and visual outcome after cataract surgery.Postgraduate teaching hospital.Refraction outcomes were recorded prospectively for a consecutive case series 1817 procedures. Complete preoperative data available 1676 eyes (92.4%). The paired mean difference between predicted achieved refraction, percentages falling within +/-0.50 diopter (D), +/-1.00 D, +/-2.00 values that contained 99% points then calculated. number final...

10.1016/s0886-3350(01)01027-6 article EN Journal of Cataract & Refractive Surgery 2002-01-01

Abstract Objective To estimate the projected population of US adults aged 18 years or older with lifetime experience doctor‐diagnosed depressive disorder from 2005–2050. Methods Based on nationally representative survey data year 2006 Behavioral Risk Factor Surveillance Survey (BRFSS), prevalence estimates depression (minor major, and dysthymia) were weighted to incorporate complex sampling design increase generalizability findings. The by age sex in then used adult based sex‐specific Census...

10.1002/gps.2061 article EN International Journal of Geriatric Psychiatry 2008-05-23

Vignettes representing mentally ill people were presented to about 2000 randomly selected residents in Bromsgrove, served by a mental hospital, and Malvern, community-based psychiatric service. They asked the likely cause of condition, what action they would take, agencies most help. In seemed more enterprising involving various tolerant. It is possible derive simple ‘action scores' as an indicator such tolerance. Although there significant demographic differences between subgroups, overall...

10.1192/bjp.162.1.99 article EN The British Journal of Psychiatry 1993-01-01
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