A5042116598- Uterine Myomas and Treatments
- Venous Thromboembolism Diagnosis and Management
- Gynecological conditions and treatments
- Prenatal Screening and Diagnostics
- Pancreatic and Hepatic Oncology Research
- Blood Coagulation and Thrombosis Mechanisms
- Endometriosis Research and Treatment
- Acute Myocardial Infarction Research
- Endometrial and Cervical Cancer Treatments
- Infectious Diseases and Tuberculosis
- Ocular Diseases and Behçet’s Syndrome
- Galectins and Cancer Biology
- scientometrics and bibliometrics research
- Macrophage Migration Inhibitory Factor
- Chronic Myeloid Leukemia Treatments
- Peripheral Neuropathies and Disorders
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- GDF15 and Related Biomarkers
- Abdominal vascular conditions and treatments
- IgG4-Related and Inflammatory Diseases
- Cardiac tumors and thrombi
- Hernia repair and management
- Ovarian cancer diagnosis and treatment
- Minerals Flotation and Separation Techniques
- Cancer Immunotherapy and Biomarkers
The University of Texas Southwestern Medical Center
2022-2024
Karyopharm Therapeutics (United States)
2023
Wroclaw Medical University
2023
University of Rochester Medical Center
2021-2023
Southwestern University
2023
Portsmouth Hospitals NHS Trust
2022
Wayne State University
2018-2021
Detroit Medical Center
2018-2021
The Barbara Ann Karmanos Cancer Institute
2020-2021
Incyte (United States)
2015-2017
343 Background: The JAK-STAT pathway plays a role in the pathogenesis of PC. In phase 2 study, JAK1/2 inhibitor Rux + C improved OS vs alone mPC pts with evidence systemic inflammation. Methods: two 3 studies, advanced/mPC only 1 prior chemotherapy regimen and C-reactive protein > 10mg/L were randomized to 21-day cycles 15 mg BID 2000 mg/m /d (day 1-14) placebo (Pb) 1-14). primary endpoint was OS. studies terminated early based on efficacy findings planned interim analysis for J1, J2...
John Hunter Hospital is the major trauma centre for a region covering more than 25,000 square kilometres. The helicopter primary retrieval service paramedic staffed and protocol driven. aim of present study was to assess overtriage rate created by such protocols, benefit patient outcomes that may be attributable service.The database used identify all cases arriving in 1996, as well their demographic details, injury severity score, details accident outcome. An expert panel reviewed medical...
Surveillance and identification of umbilical cord abnormalities is a challenging problem in obstetrics. Continuous fetal monitoring during active labor helps identify when danger exists for the fetus.A nullipara underwent emergent cesarean delivery distress was found to have fetus already separated from completely torn cord. The 17 cm length, centrally attached, pale, without bleeding vasospasm. newborn initially pale but had hemoglobin 17.4 g survived.The incidence rupture utero rare has...
Pleural epithelioid hemangioendothelioma (EHE) is a rare malignancy of vascular origin. It can affect various organs; pleural involvement and lack suspicion leads to delay in diagnosis. We present case EHE with metastasis lung parenchyma that presents chest pain dyspnea. Chest imaging showed loculated effusion, thickening, mediastinal lymphadenopathy, pulmonary nodules.
TPS4146 Background: The systemic inflammatory response characteristic of PC is mediated in part by JAK-STAT signaling and may contribute to local tumor growth disease-related weight loss, decreased muscle mass, poor performance status. In the phase II, randomized, double-blind RECAP study, combination JAK1/JAK2 inhibitor ruxolitinib with capecitabine improved overall survival (OS) versus placebo + patients mPC elevated C-reactive protein (CRP) levels or a modified Glasgow Prognostic Score...
Anti- N -methyl-D-aspartate receptor (NMDAR) encephalitis is an autoimmune disease frequently associated with ovarian teratomas. In cases where teratoma identified, treatment involves prompt removal of the teratoma, resulting in significant clinical improvement and decreased incidence relapse. We present case a 14-year-old female patient admitted for progressively worsening psychiatric neurological status, diagnosed anti-NMDAR encephalitis, negative initial imaging pathology. She was...
Background: Mortality from ovarian cancer remains high due to the lack of methods for early detection. The difficulty lies in low prevalence disease necessitating a significantly specificity and positive-predictive value (PPV) avoid unneeded invasive intervention. Currently, antigen- 125 (CA-125) is most commonly used biomarker detection cancer. In this study we determine combining macrophage migration inhibitory factor (MIF), osteopontin (OPN), prolactin (PROL) with CA-125 serum samples...
Objectives HBB-related significant hemoglobinopathies have been anecdotally associated with low fetal fraction on noninvasive prenatal screening (NIPS). We sought to compare the difference in using NIPS women (HSH) and normal hemoglobin.Study design This is a retrospective case-control study. Cases were diagnosis of HSH from commercial laboratory. The comparison group was hemoglobin AA tertiary care center database. tested for differences median quantile regression analysis, adjusting...
Leiomyomas are usually easily identifiable on routine imaging. However, there is increasing difficulty with diagnosing leiomyomas following degeneration. Subserosal that undergo cystic degeneration can imitate ovarian pathology. We present the case of a 39-year-old nulligravid woman who underwent surgery for large pelvic mass originally suspected to be origin. Intraoperatively, was found originate from uterus and determined pedunculated, fluid-filled cyst arising fibroid which had undergone...
Adhesions frequently occur postoperatively, causing morbidity. In this noninterventional observational cohort study, we enrolled patients who presented for repeat abdominal surgery, after a history of previous myomectomy, from March 1998 to June 20210 at St. Vincent's Catholic Medical Centers. The primary outcome pilot study was compare adhesion rates, extent, and severity in were treated with intraperitoneal triamcinolone acetonide during the initial myomectomy (n = 31) those did not...
• Choriocarcinomas can follow molar, ectopic, or normal pregnancies. The early diagnosis and treatment of choriocarcinomas is imperative. Atypical symptoms in pregnancy should raise suspicion for choriocarcinoma. Choriocarcinoma must always be the differential uncomplicated term
Objective: Patients with cervical cancer who are diagnosed venous thromboembolism (VTE) have worse outcomes compared to those not affected. There has yet be a reliable method predict or prevent VTE in patients. Our objective is describe the incidence of patients recurrent and metastatic (r/mCC) determine risk factors that may this setting. Methods: We performed an observational cohort study 386 r/mCC received at least one line systemic chemotherapy. collected demographic, clinical,...