A5062705329- Pancreatic and Hepatic Oncology Research
- Synthesis of Indole Derivatives
- Orthopedic Infections and Treatments
- Radiomics and Machine Learning in Medical Imaging
- Immunotherapy and Immune Responses
- CAR-T cell therapy research
- Thyroid and Parathyroid Surgery
- Virus-based gene therapy research
- Thyroid Cancer Diagnosis and Treatment
- Pleural and Pulmonary Diseases
- Distributed Control Multi-Agent Systems
- MRI in cancer diagnosis
- Esophageal and GI Pathology
- Gastrointestinal Tumor Research and Treatment
- Bioactive Compounds and Antitumor Agents
- Immune cells in cancer
- Artificial Intelligence in Healthcare and Education
- Diversity and Career in Medicine
- Cardiac, Anesthesia and Surgical Outcomes
- Pancreatitis Pathology and Treatment
- Monoclonal and Polyclonal Antibodies Research
- Carbohydrate Chemistry and Synthesis
- Advances in Oncology and Radiotherapy
- Cancer Diagnosis and Treatment
- Bioactive natural compounds
Peter MacCallum Cancer Centre
2024
Medical University of South Carolina
2024
City of Hope
2021-2023
City Of Hope National Medical Center
2020-2021
Case Western Reserve University
2015-2018
MetroHealth Medical Center
2015-2018
University Hospitals of Cleveland
2016-2017
United States Naval Research Laboratory
2008
University of California, Berkeley
2008
Mount Sinai Hospital
1997
A concise synthesis of rubioncolin B is described, which features an unprecedented intramolecular Diels-Alder reaction involving ortho-quinone methide and a naphthofuran moiety. The generated through surprisingly facile tautomerization para-quinone.
Converting an immunosuppressive melanoma microenvironment into one that favors the induction of antitumor immunity is indispensable for effective cancer immunotherapy. In current study we demonstrate oat-derived β-(1-3)-(1-4)-glucan 200 kDa molecular size (BG34-200) previously shown to mediate direct interaction with macrophages could alter immune signature within microenvironment. Systemic administration BG34-200 resulted in reversion tolerant immunogenic allows M1-type activation...
Nine cases of recorded discitis are presented, in which scintigraphy played an important part the diagnosis. The patients (five men (aged 21-75 years) and four women 40-73 years)) had a history back pain varying duration from two days to three months. Final diagnosis was confirmed microbiologically (seven patients) or radiographically (two patients). Bone valuable diagnostic procedure for with earlier detection than plain radiography similar initial that third generation computed tomography....
In 51 patients treated with Yttrium-90 (Y-90) synovectomy for rheumatoid (inflammatory) arthritis (IA) and OA of the knee we found that decreased retained activity (RKA) increased extra-articular in lymph nodes liver are more likely to be IA than following bilateral injections. Joint inflammation, as assessed by radionuclide blood pool scan but not SF white cell count, correlates RKA nodes. Intra-articular steroid had no significant effect on retention or uptake. Strict hospital...
PURPOSE Preoperative prediction of postoperative complications (PCs) in inpatients with cancer is challenging. We developed an explainable machine learning (ML) model to predict PCs a heterogenous population undergoing same-hospitalization major operations. METHODS Consecutive who underwent operations from December 2017 June 2021 at single institution were retrospectively reviewed. The ML was and tested using electronic health record (EHR) data 30-day for patients Clavien-Dindo grade 3 or...
Abstract Tumour metastasis to the jaw is an uncommon finding. When it does present, usually evidence of widespread metastatic disease and represents unfavourable prognostic indicator. The clinical presentation in can vary may occur oral soft tissues, subcutaneous tissues adjacent bone, mandible or maxillary alveolus mimic dental pathology. radiographic appearance most commonly expansive, lytic lesion with irregular borders. This case report describes otherwise medically well 76‐year‐old male...
Rubioncolin B is isolated from the roots of Rubia species which are administered in Chinese medicine. The short synthesis depicted features tautomerization p-quinone I to o-quinone methide J then undergoes an intramolecular Diels-Alder reaction give complex ring system target.
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at glance that was extracted from about 200 leading journals. To access of an article which published elsewhere, please select “Full Text” option. The original trackable via the “References”
Abstract Purpose: The purpose of this study is to define the best CT perfusion analytical method for surgical candidacy pancreatic cancer patients in Neo-Adjuvant treated clinical trial population. Experimental Design: Study was designed assess tumor status. This prospective involved 24 adult with adenocarcinoma (PDAC). Inclusion criteria included, histologically or cytologically confirmed resectable, borderline locally advanced (unresectable) PDAC. All received neoadjuvant therapy...