- Surgical Simulation and Training
- Esophageal Cancer Research and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Pancreatic and Hepatic Oncology Research
- Cutaneous Melanoma Detection and Management
- Gastric Cancer Management and Outcomes
- Esophageal and GI Pathology
- Cardiac, Anesthesia and Surgical Outcomes
- Cannabis and Cannabinoid Research
- COVID-19 and healthcare impacts
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Trauma and Emergency Care Studies
- Enhanced Recovery After Surgery
- Intraperitoneal and Appendiceal Malignancies
- Infection Control and Ventilation
- Injury Epidemiology and Prevention
- Diversity and Career in Medicine
- Patient-Provider Communication in Healthcare
- Trauma Management and Diagnosis
- Anatomy and Medical Technology
- Intestinal Malrotation and Obstruction Disorders
- Radiation Dose and Imaging
- Gastrointestinal Tumor Research and Treatment
- Burn Injury Management and Outcomes
- Nonmelanoma Skin Cancer Studies
St. Anthony Hospital
2024
University of Colorado Denver
2015-2024
University of Colorado Anschutz Medical Campus
2015-2024
University of Colorado Cancer Center
2022-2023
University of Colorado System
2023
City Of Hope National Medical Center
2018-2022
Society of Surgical Oncology
2022
The Medical Center of Aurora
2022
City of Hope
2019-2021
University of Colorado Hospital
2021
Background Craniosynostosis, the premature closure of calvarial sutures, results in characteristic skull deformations. Correction craniosynostosis has traditionally involved an open cranial vault remodeling procedure. A technique recently developed uses endoscope to perform a strip craniectomy conjunction with postoperative molding helmet guide growth. Few studies compare these 2 approaches treatment various forms craniosynostosis. In this study, we present single institution's experience...
Objective— The aim of our study is to determine the cellular and molecular origin for pericytes in infantile hemangioma (IH) their functional role formation pathological blood vessels. Methods Results— Here we show that IH-derived stem cells (HemSCs) form pericyte-like cells. With vitro studies, demonstrate HemSC-to-pericyte differentiation depends on direct contact with endothelial JAGGED1 expressed ectopically fibroblasts was sufficient induce HemSCs acquire a phenotype, indicating...
Humans are able to compensate for low-volume blood loss with minimal change in traditional vital signs. We hypothesized that a novel algorithm, which analyzes photoplethysmogram (PPG) wave forms continuously estimate compensatory reserve would provide greater sensitivity and specificity detect compared The index (CRI) is measure of the remaining reduced central volume, where CRI 1 represents supine normovolemia 0 circulating volume at hemodynamic decompensation occurs; values between...
Management of clinical stage III melanoma, which historically was treated with surgical therapeutic lymph node dissection (TLND), has changed significantly due to the introduction effective systemic therapies including immune checkpoint and BRAF/MEK inhibitors. We asked how interventions progression free survival overall in this population. The Flatiron Health electronic health records database for Advanced Melanoma queried patients melanoma between 2018 2022 therapy. Patients were...
Humans are able to compensate for significant blood loss with little change in traditional vital signs. We hypothesized that an algorithm, which recognizes compensatory changes photoplethysmogram (PPG) waveforms, could detect active bleeding and ongoing volume injured patients.Injured adults were prospectively enrolled at a level I trauma center. PPG data collection was conducted using custom-made pulse oximeter. Waveform post-processed by algorithm calculate the reserve index (CRI),...
Enhanced recovery after surgery (ERAS) protocols for gastric cancer patients have shown improved outcomes in Asia. However, data on ERAS (GC-ERAS) programs the United States are sparse. The purpose of this study was to compare perioperative before and implementation an GC-ERAS protocol at a National Comprehensive Cancer Center States.We reviewed medical records surgically treated with curative intent from January 2012 October 2016 compared group (November 1, 2015-October 2016) historical...
Humans are able to compensate for significant loss of their circulating blood volume, allowing vital signs remain relatively stable until compensatory mechanisms overwhelmed. The authors present several clinical and performance case studies in an effort demonstrate real-time measurements individual's reserve acute changes volume. This measurement is referred as the Compensatory Reserve Index (CRI).We identified seven two physical conditions relevant military casualty operational medicine...