A5051827413- Childhood Cancer Survivors' Quality of Life
- Glioma Diagnosis and Treatment
- Acute Lymphoblastic Leukemia research
- Family Support in Illness
- Cancer survivorship and care
- Palliative Care and End-of-Life Issues
- Cancer-related cognitive impairment studies
- Brain Metastases and Treatment
- Pituitary Gland Disorders and Treatments
- Advanced Radiotherapy Techniques
- COVID-19 and healthcare impacts
- COVID-19 and Mental Health
- Cerebrospinal fluid and hydrocephalus
- Healthcare professionals’ stress and burnout
- Adolescent and Pediatric Healthcare
- Family and Patient Care in Intensive Care Units
- Global Cancer Incidence and Screening
- Genital Health and Disease
- Religion, Spirituality, and Psychology
- Meningioma and schwannoma management
- Breast Implant and Reconstruction
- Congenital Diaphragmatic Hernia Studies
- Lung Cancer Diagnosis and Treatment
- Anesthesia and Neurotoxicity Research
- Head and Neck Cancer Studies
Tata Memorial Hospital
2014-2025
Homi Bhabha National Institute
2017-2025
Peter MacCallum Cancer Centre
2024
The University of Melbourne
2024
Advanced Centre for Treatment, Research and Education in Cancer
2022
Abstract Background The evolving treatment paradigm in children and adolescents with craniopharyngioma (CP) aims at minimizing late functional sequelae. Advanced radiotherapeutic techniques offer theoretical advantages of preserving neurological functions, however, clinical evidence such is limited. current study constitutes a secondary analysis CP patients Randomized Control Trial testing Conventional RT (ConvRT) versus Stereotactic Conformal Radiotherapy (SCRT)(NCT00517959). Methods...
PURPOSE The number of cancer survivors living with and beyond treatment is rising globally. It fundamental to understand the extent type psychosocial care services offered worldwide. We evaluated models survivorship care, practices in post-treatment phase, barriers/facilitators delivery services, including low- middle-income countries (LMICs). METHODS International Psycho-Oncology Society (IPOS) Survivorship Special Interest Group led a cross-sectional online survey between March November...
PURPOSE Despite an increasing number of survivors childhood cancer (CCS) in low- and middle-income countries, survivorship care is its nascent stages. We describe the spectrum late effects seen, challenges faced, lessons learnt over three decades a program India. METHODS demographics profile all CCS enrolled our After Completion Treatment Clinic from February 5, 1991 (inception) to 4, 2021. analyzed trends by decade diagnosis. RESULTS There were 3,067 survivors, median age was 18 years...
PURPOSE To evaluate stress levels among the health care workers (HCWs) of radiation oncology community in Asian countries. METHODS HCWs departments from 29 tertiary cancer centers Bangladesh, India, Indonesia and Nepal were studied May 2020 to July 2020. A total 758 eligible identified. The 7-Item Generalized Anxiety Disorder, 9-Item Patient Health Questionnaire, 22-Item Impact Events Scale-Revised used for assessing anxiety, depression, post-traumatic disorder. Univariate multivariate...
Abstract Background The adverse influence of undernutrition in children with cancer may be remediated by early nutritional intervention. This study assessed the efficacy ready‐to‐use therapeutic food (RUTF) improving status and reducing treatment‐related toxicities (TRTs) such children. Methods In a randomized controlled phase‐3 open‐label trial, severely moderately undernourished were 1:1 to receive standard therapy (SNT) or SNT+RUTF for 6 weeks. primary outcome (weight gain >10%)...
Abstract Background Cancer affects mental health in older adults with cancer (OAC), affecting almost 50% of the patients. There are only a few studies on psychiatric disorders OAC, especially low resource settings. We report our real-world experience prevalence and factors associated OAC referred to psycho-oncology service an Indian tertiary care institute. Methods retrospectively analysed medical records patients aged 60 + cancer-directed treatment or follow-up for < 2 years after...
Cancer patients and their family caregivers have reported various needs that are not met. Recognition of the unmet by healthcare professionals may be a first step to adequately systematically addressing them. Thus, International Psycho-Oncology Society Survivorship Online Survey was developed measure professionals' evaluation about around globe.The survey in English translated additional 14 different languages. The distributed on web-based REDCap application over 50 psycho-oncology societies...
Abstract Purpose We describe the challenges faced and lessons learnt over three decades of a childhood cancer survivorship program in India. Methods provide descriptive analysis barriers running this program, our strategies management, detail stages development holistic support system. Results The profile late effects cohort survivors is notable for high prevalence psychosocial issues metabolic syndrome. Major difficulties were transitioning patients to care attrition follow-up, which...
Health-care staff working in oncology setting experience excessive stress, which if unrelieved can lead to burnout. Staff support groups have been found beneficial.This study aims evaluate the structure, process, and impact of a group conducted for field workers involved cancer screening an urban tertiary center developing country.Retrospective analysis care center.Prospectively maintained data with structured notes documenting process sessions was analyzed. Impact analyzed through feedback...
Families of children with cancer undergoing treatment during COVID-19 pandemic represent a vulnerable population for psychological distress and early identification remedial measures are imperative wellbeing both the caregivers. This article reports results assessment in primary caregivers at tertiary care center.Primary (≤15 years) taking our institute period July 2020 to August were prospectively evaluated using Patient Health Questionnaire-9 (PHQ-9) Generalized Anxiety Disorder-7 (GAD-7)...
19 Background: To assess the evaluation of late effects in childhood cancer survivors who have transitioned to AYA age group on longitudinal follow up After Completion Therapy (ACT) clinic at Tata Memorial Hospital, Mumbai. Methods: ACT database was analyzed for attained 15-30 yrs last demographics, grade &pattern up. Results: Of 1720 Survivors ( > , 2 off therapy & disease free) registered from Feb 91-Feb15, 976(56.7%) are group, M.F = 707/269 (2.6:1), Hematolymphoid : Solid...
Abstract Introduction Psychological concerns are common in children and adolescents with cancer, for which they require referral to specialist services. There is a dearth of pediatric psycho-oncology services India. limited studies on emotional related distress children. Objectives To evaluate the types problems associated factors cancer referred service tertiary care oncology center Materials Methods A retrospective analysis all referrals institution's over 5 years was performed. Patients...
The purpose of this study was to report long-term neurocognitive and clinical outcomes in children treated for average-risk medulloblastoma with hyperfractionated radiation therapy (HFRT) alone.Between 2006 2010, 20 rigorously staged were on a prospective HFRT without upfront adjuvant systemic chemotherapy after written informed consent. delivered as twice-daily fractions (1 Gy/fraction, 6-8 hours apart, 5 days/week) craniospinal axis (36 Gy/36 fractions) plus conformal tumor-bed boost (32...
Abstract Background: The Hospital and Anxiety Depression Scale (HADS) is useful for screening depression anxiety in cancer. It has not been validated the Marathi language, which third most common language India. We aimed to examine reliability validity of Marathi-translated version HADS cancer patients their caregivers. Methods: In a cross-sectional study design, we administered Scale-Marathi (HADS-Marathi) 100 participants (50 50 caregivers) after obtaining informed consent. team...
2035 Background: Evidence for modern conformal partial brain radiotherapy is largely on retrospective or small case-series. We report longitudinal detailed neuropsychological outcomes from a prospective randomized trial comparing high-precision (CRT) versus conventional (Conv RT) in children and young adults with progressive/residual benign low-grade tumors (NCT00517959). Methods: Between 2001-10, 200 patients (132 males, 68 females; median age 13 years) were to receive CRT (n=105; multiple...
46 Background: Ugam is a support group of childhood cancer survivors from After Completion Treatment (ACT) clinic at Tata Memorial Hospital (TMH), functioning under umbrella Indian Cancer Society (ICS), not for profit organisation. Ugam’s mission empowerment and advocacy. ACT-Ugam has provided role model holistic care to survivors.Project PICASSO (Partnership in Survivorship Optimization) developed by ICS promote & facilitate paediatric unit (PCU) based ACT provide psychosocial across...