A5048053034- Pain Management and Placebo Effect
- Gastrointestinal motility and disorders
- Stress Responses and Cortisol
- Pain Mechanisms and Treatments
- Ovarian function and disorders
- Health, psychology, and well-being
- Complementary and Alternative Medicine Studies
- Pediatric Pain Management Techniques
- Tryptophan and brain disorders
- Musculoskeletal pain and rehabilitation
- Psychosomatic Disorders and Their Treatments
- Acupuncture Treatment Research Studies
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Music Therapy and Health
- Sleep and related disorders
- Dermatology and Skin Diseases
- Diet and metabolism studies
- Heart Rate Variability and Autonomic Control
- Empathy and Medical Education
- Inflammatory Bowel Disease
- Infant Health and Development
- Neuroscience and Music Perception
- Reproductive Biology and Fertility
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Neuroendocrine regulation and behavior
Ruhr University Bochum
2020-2024
University of Duisburg-Essen
2015-2024
Essen University Hospital
2013-2023
University of Bonn
2003-2023
Deutsche Schmerzgesellschaft
2022
Israelitisches Krankenhaus
2022
Institut für Medizinische Informatik, Biometrie und Epidemiologie
2004-2017
Essen BioScience (United States)
2016
In-Q-Tel
2015
University of Zurich
2009
The aim of this study was to compare the performance fecal lactoferrin (Lf), calprotectin (Cal), polymorphonuclear neutrophil elastase (PMN-e), as well serum C-reactive protein (CRP) in patients with inflammatory bowel diseases (IBD) address (a) whether these markers can differentiate IBD endoscopically assessed inflammation from without and irritable syndrome (IBS); (b) they correlate endoscopic severity inflammation; (c) a combination respective disease-specific activity indices may...
Abstract Polycystic ovary syndrome (PCOS) is a common endocrine disorder characterized by chronic anovulation and hyperandrogenism. PCOS one of the leading causes infertility manifests with hirsutism, acne, obesity. To investigate its impact on health-related quality life sexuality, 50 women controls were evaluated standardized questionnaires (36-item short-form health survey, symptom checklist revised, satisfaction questionnaire). The obesity, was assessed using five-point rating scales,...
Objective : Polycystic ovary syndrome (PCOS) has been shown to cause a reduction in quality of life. This study examines the extent different PCOS symptoms on quality-of-life, psychosocial well-being and sexual satisfaction. Methods Complete metabolic, hormonal, clinical data were obtained from total 120 women with PCOS. Patients compared 50 healthy establish reductions quality-of-life emotional well-being. In addition, correlation between variables major features obesity (body mass index...
BACKGROUND: The goal was to study the effects of social support during pregnancy on maternal depressive symptoms, quality life and outcomes. METHODS: Eight hundred ninety-six women were prospectively studied in first trimester following completion pregnancy. sample divided into quartiles yielding groups low, medium high based perceived support. RESULTS: Pregnant with low reported increased symptoms reduced life. outcomes particularly pronounced who had smoked pregnancy, significant main a...
<h3>Objective</h3> To address the role of anxiety and depression symptoms in altered pain processing irritable bowel syndrome (IBS). <h3>Design</h3> In this functional magnetic resonance imaging study, blood oxygen level-dependent (BOLD) response to rectal distensions delivered at previously determined individual discomfort thresholds was assessed. <h3>Patients</h3> 15 female patients with (IBS) normal thresholds, 12 healthy women. <h3>Measures</h3> The correlation symptoms, measured...
Study Objectives:The study goal was to investigate autonomic activity with heart rate variability analysis during different sleep stages in males and females.
<i>Background:</i> The aim of this study was to investigate the effects mind-body therapy on neuroendocrine and cellular immune measures, health-related quality life disease activity in patients with ulcerative colitis (UC) remission. <i>Methods:</i> Thirty UC remission or low were randomly assigned an intervention group (n = 15) a usual-care waiting control 15). Intervention consisted structured 60-hour training program over 10 weeks which included stress management...
Comparatively little attention has been paid to the symptoms of anxiety in polycystic ovary syndrome (PCOS), although disorders constitute most common psychiatric diagnoses among endocrine patients and general population. Therefore, our goal was address prevalence, determinants implications alone or combination with depression German women PCOS. In this nation-wide, internet-based survey, (Hospital Anxiety Depression Scale, HADS) quality life (SF-12) were assessed together sociodemographic...
Perceived stress seems to be a risk factor for exacerbation of ulcerative colitis. Yoga has been shown reduce perceived stress.To assess the efficacy and safety yoga improving quality life in patients with colitis.A total 77 (75% women; 45.5 ± 11.9 years) colitis clinical remission but impaired were randomly assigned (12 supervised weekly sessions 90 min; n = 39) or written self-care advice (n 38). Primary outcome was disease-specific (Inflammatory Bowel Disease Questionnaire). Secondary...
Altered pain anticipation likely contributes to disturbed central processing in chronic conditions like irritable bowel syndrome (IBS), but the learning processes shaping expectation of remain poorly understood. We assessed neural circuitry mediating formation, extinction, and reactivation abdominal pain-related memories IBS patients compared healthy controls (HC) a differential fear conditioning paradigm.During acquisition, predictive visual cues (CS(+)) were paired with rectal distensions...
<h3>Objective</h3> Understanding the neural circuitry of placebo analgesia in context visceral pain is increasingly important given evidence clinical benefit treatment IBS. This functional MRI study addressed IBS, UC and healthy control (HC) volunteers. <h3>Design</h3> Painful rectal distensions were delivered N=17 patients with IBS , N=15 remission, sex-matched age-matched HCs an adaptation phase followed by intravenous application saline combined either positive instructions relief...
To evaluate the diagnostic use of fecal concentrations lactoferrin (Lf), calprotectin (Cal), polymorphonuclear neutrophil-elastase (PMN-e), and lysozyme (Lys) as indicators disease activity in patients with active inactive ulcerative colitis (UC).A total 76 specimens were collected from 31 UC times status disease. Disease was determined index (CAI; Rachmilewitz index), which includes a combination laboratory parameters clinical symptoms, score at least 6 indicating Fecal Lf, Cal, PMN-e, Lys...