Jhony Anacleto-Santos

ORCID: 0000-0002-6538-9788
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Research Areas
  • Toxoplasma gondii Research Studies
  • Phytochemical compounds biological activities
  • X-ray Diffraction in Crystallography
  • Synthesis and Characterization of Heterocyclic Compounds
  • Crystallization and Solubility Studies
  • Bee Products Chemical Analysis
  • Vanadium and Halogenation Chemistry
  • Phytochemistry and Biological Activities
  • Insect and Pesticide Research
  • Insect Pest Control Strategies
  • Environmental Toxicology and Ecotoxicology
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Metal complexes synthesis and properties
  • Biological Activity of Diterpenoids and Biflavonoids
  • Toxin Mechanisms and Immunotoxins
  • Parasitic Infections and Diagnostics
  • Fern and Epiphyte Biology
  • Cytomegalovirus and herpesvirus research
  • Cassava research and cyanide
  • Natural product bioactivities and synthesis
  • Antimicrobial Peptides and Activities
  • Advances in Cucurbitaceae Research

Universidad Nacional Autónoma de México
2022-2025

Universidad Autónoma de la Ciudad de México
2024

Universidad Autónoma Metropolitana
2018-2019

Pleopeltis crassinervata has demonstrated antimicrobial effects, including anti-Toxoplasma activity, which been attributed to the presence of compounds such as terpenes and fatty acid methyl esters. In this study, effects P. hexane subfraction one (Hsf1) on Toxoplasma gondii tachyzoite ultrastructure were evaluated using TEM SEM, lytic cycle processes adhesion, invasion, proliferation phase-contrast microscopy. Additionally, antioxidant capacity its main (phytol hexadecenoic ester)...

10.3390/antiox14030342 article EN cc-by Antioxidants 2025-03-14

Pleopeltis crassinervata (Pc) is a fern that, according to ethnobotanical records, used in Mexican traditional medicine treat gastrointestinal ailments. Recent reports indicate that the hexane fraction (Hf) obtained from Pc methanolic frond extract affects Toxoplasma gondii tachyzoite viability vitro; therefore, present study, activity of different subfractions (Hsf) by chromatographic methods was evaluated same biological model. Gas chromatography/mass spectrometry (GC/MS) analysis carried...

10.3390/antibiotics12050889 article EN cc-by Antibiotics 2023-05-10

During Toxoplasma gondii chronic infection, certain internal factors that trigger the proliferation of neural progenitor cells (NPCs), such as brain inflammation, cell death, and changes in cytokine levels, are observed. NPCs give rise to neuronal types adult some mammals. capable dividing differentiating into a restricted repertoire glial types. In this study, was evaluated CD-1 male mice chronically infected with T. ME49 strain. Histological sections from were order observe tissue cysts....

10.3390/microorganisms11112671 article EN cc-by Microorganisms 2023-10-31

is a fern documented in ethnobotanical records for its use Mexican traditional medicine to treat gastric disorders and mouth ulcers. Consequently, conducting biological pharmacological assays crucial validate the therapeutic efficacy of this plant within context medicine. In present study, we investigated activity extracts fractions obtained from

10.3390/pharmaceutics16050624 article EN cc-by Pharmaceutics 2024-05-07

Abstract Tetrahedral copper(II) and zinc(II) coordination compounds from 5-nitroimidazole derivatives, viz . 1-(2-chloroethyl)-2-methyl-5-nitroimidazole (cenz) ornidazole 1-(3-chloro-2-hydroxypropyl)-2-methyl-5-nitroimidazole (onz), were synthesized spectroscopically characterized. Their molecular structures determined by X-ray diffraction studies. The complexes [Cu(onz) 2 X ], [Zn(onz) [Cu(cenz) ] [Zn(cenz) (X − = Cl, Br), are stable in solution exhibit positive LogD 7.4 values that the...

10.1007/s00775-023-02029-7 article EN cc-by JBIC Journal of Biological Inorganic Chemistry 2023-12-15

The indiscriminate use of herbal products is increasingly growing worldwide; nonetheless consumers are not warned about the potential health risks that these may cause. Hintonia latiflora (Hl) a tree native to American continent belonging Rubiaceae family and its stem bark empirically used mainly treat diabetes malaria; supplements containing Hl sold in America Europe without medical prescription, thus scientific information regarding toxicity as consequence regular consumption needed. In...

10.14670/hh-18-016 article EN PubMed 2018-12-01
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