A5014643643- Antibiotic Resistance in Bacteria
- Bacterial Infections and Vaccines
- Bacterial biofilms and quorum sensing
- Vibrio bacteria research studies
- Antibiotic Use and Resistance
- Pneumonia and Respiratory Infections
- Infective Endocarditis Diagnosis and Management
- Infections and bacterial resistance
- Escherichia coli research studies
- Hepatitis Viruses Studies and Epidemiology
- Brucella: diagnosis, epidemiology, treatment
- Enterobacteriaceae and Cronobacter Research
- Antimicrobial Resistance in Staphylococcus
- Plant Pathogenic Bacteria Studies
- Urinary Tract Infections Management
- Streptococcal Infections and Treatments
- Botulinum Toxin and Related Neurological Disorders
- Viral gastroenteritis research and epidemiology
- Antibiotics Pharmacokinetics and Efficacy
- Biosensors and Analytical Detection
- Influenza Virus Research Studies
- Bacteriophages and microbial interactions
- Antimicrobial Peptides and Activities
- Vector-Borne Animal Diseases
- Burn Injury Management and Outcomes
Pasteur Institute of Iran
2015-2025
Nowadays, zinc oxide nanoparticles (ZnO NPs) have been shown to exhibit potent antibacterial activity against a wide range of pathogenic bacteria. Numerous investigations delved into exploring the activities exhibited by ZnO NPs. Notwithstanding, correlation between morphology these and their resultant impacts remains an area demanding further exploration across varying morphological variations. This paper presents comparative study on how affects efficacy. In this regard, NPs with different...
New Delhi metallo-beta-lactamase (NDM-1) is a novel (MBL). Sporadic cases of NDM-1 positive strains have been reported from different countries, suggesting widespread dissemination. The aim this study was the detection MBLs in Enterobacteriaceae isolated patients Tehran hospitals. After identification tests, susceptibility to antibiotics done by Kirby-Bauer method and broth microdilution. Carbapenem-resistant isolates were tested for carbapenemase production using modified Hodge test (MHT)....
Carbapenem-resistant Enterobacterales (CRE) is an increasing problem worldwide. Here, we examined the clonal relatedness of 71 non-repetitive CRE isolates collected in a university hospital Tehran, Iran, between February 2015 and March 2016. Pulsed-field gel electrophoresis (PFGE) MLST were used for epidemiological analysis. Screening antibiotic resistance genes, PCR-based replicon typing, conjugation experiments, optical DNA mapping also performed. Among all isolates, 47 Klebsiella...
Resistant and virulent strains of Klebsiella pneumoniae (K. pneumoniae) are rapidly disseminated among both hospitalized patients communities, therefore, the identification genes responsible for virulence resistance, along with clonal relatedness these strains, could be beneficial in management dissemination patients. The aim present study was to assess antibiotic susceptibility, resistance genes, as well genetic K. isolated from admitted four hospitals Mazandaran, Iran. A total 95 were...
Objective(s) Different types of extended spectrum beta-lactamases (ESBLs) are encountered in the clinical settings worldwide. There a few studies regarding prevalence ESBL genes among Klebsiella pneumoniae isolates at Tehran especially those blaPER and blaCTX. The aim this study was to determine blaSHV, blaTEM ,blaPER blaCTX K. different hospitals Tehran. Materials Methods Two hundred were received from specimens. susceptibility 10 antibiotics examined by disk diffusion test. MICs for...
Pertussis caused by Bordetella pertussis, remains a public health problem worldwide, despite high vaccine coverage in infants and children many countries. Iran has been using whole cell for the last 50 years with more than 95% vaccination rate since 1988 experienced pertussis resurgence recent years. Here, we sequenced 55 B. isolates mostly collected from three provinces highest number of cases Iran, including Tehran, Mazandaran, Eastern-Azarbayjan period 2008-2016. Most carried ptxP3/prn2...
Background The global spread of plasmids carrying carbapenemase genes within carbapenem resistant Acinetobacter baumannii (CRAB) strains poses a worldwide public health issue. In this study, we conducted comprehensive genetic analysis and chromosomes harboring the major ( bla NDM , KPC VIM IMP GES OXA-58 -like, OXA-24/40 OXA-143 OXA-23 -like) in CRAB using bioinformatic tools. Methods We retrieved from GenBank. size, replicon type, conjugal apparatus were also determined. Furthermore, allele...
Abstract Background Escherichia coli serogroup O25b - sequence type 131 ( E. O25-B2-ST131) is considered as multidrug-resistant and hypervirulent organism. There lack of data about involvement this pathogen in the children’s infection. In study, prevalence, clonality, virulence capacity, antibiotic resistance phenotype genotype O25-B2-ST131 compared with non-O25-B2-ST131 isolates were investigated children urinary tract infection Tehran, Iran. Methods The from urine samples identified using...
Abstract Hospital wastewater can contaminate the environment with antibiotic-resistant and virulent bacteria. We analyzed samples from four hospitals in Ardabil province, Iran for Enterococcus faecium faecalis using culture molecular methods. also performed antimicrobial susceptibility testing polymerase chain reaction resistance virulence genes. Out of 141 enterococci isolates, 68.8% were E. 23.4% faecalis. Ciprofloxacin rifampicin showed highest level against isolates at 65%. High-level...
Leptospirosis is a zoonotic disease caused by pathogenic
Pseudomonas aeruginosa is a major cause of healthcare-associated infections (HAIs), particularly in immunocompromised patients, leading to high morbidity and mortality rates. This study aimed investigate the antimicrobial resistance patterns, virulence gene profiles, genetic diversity among P. isolates from hospitalized patients Mazandaran, Iran. From September 2021 April 2022, 82 non-duplicate were collected diverse clinical sources. Identification was confirmed using API 20 NE (bioMérieux,...
Objectives Pertussis remains endemic despite high vaccine coverage in infants and toddlers. vaccines confer protection but immunity wanes overtime boosters are needed a lifetime. Iran, eligible for the Expanded Program on Immunization that includes primary immunization, implemented two additional booster doses using whole-cell (wPV) at 18 months-old about 6 years-old. Duration of induced by wPVs currently use their impact as pre-school not well documented. This study aimed assessing...
The human T-cell leukemia virus type 1 (HTLV-1) is a positive single-stranded RNA that belongs to the delta retrovirus family. As result, vaccine candidate can be recognized by B cells and T good for generating durable immune response. Further, GPEHT protein multi-epitope designed based on Gag, Pol, Env, Hbz, Tax proteins of HTLV-1. In developing suitable effective against HTLV-1, selection (GPEHT) with formulation an alum adjuvant was conducted. this study, we assessed potential stimulating...
Abstract Background Extended-spectrum beta-lactamase-producing enterobacteria (ESBL-PE) in carriers have become a global health problem. Using molecular typing techniques, including PFGE, could be useful to determine the source of bacterial dissemination. The current study aimed investigate intestinal carriage ESBL-producing E. coli (ESBL-EC) and clonal relatedness among ESBL-EC isolated from hospitalized outpatient fecal Iran. Methods A total 120 rectal swabs were collected; 50.8% (61/120)...