A5048189316- Bone Tissue Engineering Materials
- Bone and Dental Protein Studies
- Bone health and osteoporosis research
- Nanoplatforms for cancer theranostics
- Graphene and Nanomaterials Applications
- Orthopaedic implants and arthroplasty
- X-ray Diffraction in Crystallography
- Nanoparticle-Based Drug Delivery
- MXene and MAX Phase Materials
- Immune cells in cancer
- Nuclear Physics and Applications
- Cancer, Lipids, and Metabolism
- Kidney Stones and Urolithiasis Treatments
- Analytical Chemistry and Chromatography
- Adipokines, Inflammation, and Metabolic Diseases
- Adipose Tissue and Metabolism
- Metabolomics and Mass Spectrometry Studies
- Extracellular vesicles in disease
- 3D Printing in Biomedical Research
- Dermatological and Skeletal Disorders
- Mass Spectrometry Techniques and Applications
- Electrospun Nanofibers in Biomedical Applications
- X-ray Spectroscopy and Fluorescence Analysis
- Tissue Engineering and Regenerative Medicine
- Metal and Thin Film Mechanics
Griffith University
2023-2025
Shandong University
2024
Queensland University of Technology
2022-2023
Australian Regenerative Medicine Institute
2022-2023
The University of Queensland
2018-2023
Barrier membranes for guided tissue regeneration are essential bone repair and regeneration. The implanted may trigger early inflammatory responses as a foreign material, which can affect the recruitment differentiation of cells during purpose this study was to determine whether immobilizing interleukin 4 (IL4) on plasma immersion ion implantation (PIII)-activated surfaces alter osteo-immunoregulatory characteristics produce pro-osteogenic effects. In order immobilize IL4, polycaprolactone...
Abstract The temporary transition of macrophages from a pro‐inflammatory (M1) to an anti‐inflammatory (M2) is crucial for tissue repair and regeneration processes. Selectively targeting M1 preferred modulate inflammatory responses. However, macrophage populations are inherently heterogeneous, the competitive phagocytosis nanoparticles (NPs) by these two subtypes has not been thoroughly investigated. This study establishes 3D cell co‐culture system evaluate M1‐targeting NPs under dynamic...
Biomineralization is a process that leads to the formation of hierarchically arranged structures in mineralized tissues, such as bone and teeth. Extensive research has been conducted on crystals bones teeth, with aim understanding underlying mechanisms mineralization process. Pathological/ectopic mineralization, kidney stones, calcific tendinitis, skeletal fluorosis, shares some similar features but different physiological mineralization. A better will provide new perspectives for treating...
Bone, a mineralized tissue, continuously undergoes remodeling, process that engages the mineralization and demineralization of bone matrix, orchestrated by interactions among cells cell-secreted biomolecules under ionic microenvironment. The osteoinductive properties demineralized organic matrix many biological factors have been well-investigated. However, impact environment (BIE) on cell differentiation osteogenesis remains largely unknown. In this study, we extracted isolated inorganic...
The identification, uptake, and clearance of nanoparticles (NPs) by phagocytes are critical in NP-based therapeutics. cell membrane coating technique has recently emerged as an ideal surface modification approach to help NP bypass phagocytosis. CD47, a regulatory protein for phagocytosis, is glycoprotein expressed on all types, including platelets. Herein, we enclosed bioactive glass (BG) with platelet bestow BG unique functions immune evasion immunomodulation. Compared the uncoated...
Hyperlipidemia-induced osteoporosis is marked by increased bone marrow adiposity, and treatment with statins for hyperlipidemia often leads to new-onset osteoporosis. Endosome-associated trafficking regulator 1 (ENTR1) has been found interact different proteins in pathophysiology, but its exact role adipogenesis not yet understood. This research aimed explore the of ENTR1 discover a new small molecule that targets evaluating effectiveness treating hyperlipidemia-induced We expression during...
Large-scale mammalian cell culture is essential in therapy, vaccine production, and the manufacturing of therapeutic protein drugs. Due to adherent growth characteristic most types, combination carrier bioreactor a common choice large-scale culture. Current carriers developed by polymer crosslinking, lithography, or emulsion drops are unable obtain structure with uniformed porous interior design, which results an inhomogeneous condition for cells therefore cannot ensure optimal dynamic...