A5021808340- Cerebral Palsy and Movement Disorders
- Neonatal and fetal brain pathology
- Infant Development and Preterm Care
- Family and Disability Support Research
- Epilepsy research and treatment
- Childhood Cancer Survivors' Quality of Life
- Prenatal Screening and Diagnostics
- Neurogenetic and Muscular Disorders Research
- Fetal and Pediatric Neurological Disorders
- Child and Adolescent Health
- Pharmacological Effects and Toxicity Studies
- Healthcare Policy and Management
- Ethics and Legal Issues in Pediatric Healthcare
- Child Nutrition and Feeding Issues
- Neonatal Respiratory Health Research
- Connective tissue disorders research
- Oral and Craniofacial Lesions
- Social Media in Health Education
- Diet and metabolism studies
- Dysphagia Assessment and Management
- Geriatric Care and Nursing Homes
- Genetics and Neurodevelopmental Disorders
- Infectious Encephalopathies and Encephalitis
- Cystic Fibrosis Research Advances
- Primary Care and Health Outcomes
Royal Children's Hospital
2014-2024
Murdoch Children's Research Institute
2015-2024
The University of Melbourne
2015-2024
Royal Hospital for Neuro-disability
2023
Ballarat Health Services
2014
Respiratory illness is the leading cause of mortality in children with cerebral palsy (CP). Although risk factors for developing chronic respiratory have been identified, comprehensive clinical care recommendations prevention and management do not currently exist. We invited over 200 clinicians researchers from multiple disciplines expertise CP to develop using a modified Delphi method on basis RAND Corporation–University California Los Angeles Appropriateness Method. These are intended use...
OBJECTIVE: The goal of this study was to describe the prevalence, syndromes, and evolution seizure disorders in children with cerebral palsy (CP) due white matter injury (WMI). METHODS: For population-based cohort study, brain MRI scans medical records were reviewed Victorian Cerebral Palsy Register born between 1999 2006 recorded as having WMI. Children excluded if they had features an undiagnosed syndrome, associated cortical malformation or injury, no contact preceding year. Included 166...
Seizures occur in approximately one-third of children with cerebral palsy. This study aimed to determine epilepsy syndromes seizures and palsy due vascular injury, anticipating that this would inform treatment prognosis. We studied a population-based cohort prenatal or perinatal injuries, born 1999-2006. Each child's MRI was reviewed characterize patterns grey white matter injury. Children syndromic likely genetic causes were excluded, given their inherent association our aim homogeneous...
We report a case of prophylactic management with methylene blue (MB) in an almost 4-year-old male congenital methemoglobinemia type II. He has CYB5R3 compound heterozygote mutation, causing cytochrome-b(5) reductase deficiency. Since the MB treatment regimen commenced, his methemoglobin level been significantly lower. shown modest behavioral improvements (as assessed on Achenbach behavior scales). There have no iatrogenic side effects. These findings are encouraging for symptomatic...
Cerebral palsy (CP) is a broad diagnosis unbound by aetiology and based on clinical examination demonstrating abnormalities of movement or posture. CP represents static neurological condition, provided that neurodegenerative conditions, leukoencephalopathies neuromuscular disorders are excluded. In paediatrics, the genetic conditions associated with rapidly increasing, primary overlapping neurodevelopmental perhaps better categorised predominant feature such as CP, intellectual disability,...
Abstract Background Children with medical complexity (CMC) have high care needs, often unmet by traditional healthcare models. In response to this need, the Complex Care Service (CCS) at The Royal Children's Hospital (RCH), Melbourne was created. Although preliminary parent satisfaction data were available, we lacked knowledge of how various components expanded service valued and contributed overall caregiver satisfaction. Aim aims study (a) determine what caregivers value most about CCS (b)...
Intractable feeding intolerance in children with severe neurological impairment (SNI) is poorly defined and understood.(1) To describe 9 SNI, where intractable was thought to be a contributor their deterioration or death. (2) consider terminology the end of spectrum difficulties SNI.Mean age at death 10.3 years (range: 5 - 15.6), median time from palliative care referral 3.1 months. Location home (n = 3), hospice 1), hospital 5) 1 intensive care. Gastrointestinal "failure" "dysfunction" were...
Objective: To determine the frequency of paroxysmal nonepileptic events in children with cerebral palsy due to brain injury who have epilepsy and describe factors associated events. Methods: Retrospective, population-based study from Victorian CP Register born 1999–2006. Neuroimaging, medical records, electroencephalograms (EEG), EEG requests were analyzed. Results: Of included 256 children, 87 had epilepsy. EEGs (with video correlation) available for 82 87. Eighteen (18/82, 22%) epileptic...
The most common cause of morbidity and mortality in children with severe cerebral palsy (CP) is respiratory disease. BREATHE-CP (Better REspiratory Airway Treatment HEalth Cerebral Palsy) a multidisciplinary research team who have conducted on the risk factors associated CP disease, systematic review management Delphi study development consensus for prevention disease CP. These strategies not been investigated; therefore, it known if implementation feasible, they improve patient outcomes or...
Abstract Background Obtaining peripheral intravenous catheter (PIVC) access in children with severe neurological impairment (SNI) is often challenging and commonly associated complications, including dislodgement, phlebitis extravasation. In cases, extravasation injury may lead to tissue necrosis, ulceration long‐term morbidity. The aim of this study was determine the relative incidence PIVC complications secondary lower limb cannulation, compared upper limb, SNI. Methods A single centre,...
'Jake is a 15-year-old boy, with cerebral palsy and global developmental delay'. As paediatricians, one of our key tasks to assess child's development. We monitor the domains gross motor, fine speech language (expressive receptive), as well social skills abilities. ensure vision hearing are normal. decide whether development on track. consider child in context their environment. explore for 'red flags' such regression or major delayed milestones, which trigger aetiological investigations...