A5009026091- Lipoproteins and Cardiovascular Health
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cancer, Lipids, and Metabolism
- Health Systems, Economic Evaluations, Quality of Life
- Lipid metabolism and disorders
- Diet and metabolism studies
- Acute Myocardial Infarction Research
- Health and Medical Research Impacts
- Hormonal Regulation and Hypertension
- Diabetes Treatment and Management
- Diabetes Management and Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Hormonal and reproductive studies
- Liver Disease Diagnosis and Treatment
- Metabolism and Genetic Disorders
- Adrenal Hormones and Disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Pharmaceutical Practices and Patient Outcomes
- Pharmaceutical Economics and Policy
- Cardiovascular Effects of Exercise
- Genetic Associations and Epidemiology
- Genomics and Rare Diseases
- Aortic Thrombus and Embolism
- Sexual Differentiation and Disorders
- Health disparities and outcomes
Royal Perth Hospital
2016-2025
The University of Western Australia
2016-2025
Fiona Stanley Hospital
2016-2025
Pathwest Laboratory Medicine
2017-2024
Sonic Healthcare (Germany)
2022
South Australia Pathology
2020
Universidad San Francisco de Quito
2019
St John of God Hospital
2011-2015
Ibero American University
2015
Diabetes Australia
2014
Objective: The optimal diet for weight loss in type 2 diabetes remains controversial. This study examined a low-carbohydrate, high-fat with detailed physiological assessments of insulin sensitivity, glycemic control, and risk factors cardiovascular disease. Methods: Fourteen obese patients (body mass index [BMI] 40.6 ± 4.9 kg/m2) were recruited an "Atkins"-type low-carbohydrate diet. Measurements made at 0, 12, 24 weeks weight, HbA1c, lipids, blood pressure. Results: Twelve completers lost...
The gold standard for diagnosing familial hypercholesterolemia (FH) is identification of a causative pathogenic mutation. However, genetic testing expensive and not widely available. To compare the validity Dutch Lipid Clinic Network (DLCN), Simon Broome (SB), Make Early Diagnosis to Prevent Deaths (MEDPED), American Heart Association (AHA) criteria in predicting an FH-causing An adult cohort unrelated patients referred lipid clinic testing. Odds ratio (OR), area under curve (AUC),...
Background Familial hypercholesterolaemia (FH) is an inherited disorder characterized by increased serum low-density lipoprotein (LDL)-cholesterol concentrations and premature atherosclerotic cardiovascular disease. The majority of people with FH are currently undiagnosed. We sought to determine the ability a community laboratory screen for individuals potential FH. Methods Serum LDL-cholesterol issued private in Western Australia were reviewed over one-year period (1 May 2010 31 April...
Background Elevated lipoprotein(a) (Lp[a]) and familial hypercholesterolemia (FH) are inherited lipid disorders. Their frequencies, coexistence, associations with premature coronary artery disease (CAD) in patients admitted to the care unit (CCU) remain be defined. Hypothesis Lp(a) FH commonly encountered among CCU independently associated increased CAD risk. Methods Plasma concentrations were measured consecutive an acute syndrome (ACS) or prior history of for 6.5 months. was defined as...
Diagnostic tools for familial hypercholesterolemia (FH) rely on estimation of LDL cholesterol concentration. However, routine measurement or calculation concentration using the Friedewald equation contains a contribution from lipoprotein(a) [Lp(a)]. We investigated whether Lp(a) influences phenotypic diagnosis FH by commonly used clinical criteria.A cohort 907 adult index patients attending clinic were studied. The Dutch Lipid Clinic Network (DLCN) and Simon Broome (SB) diagnostic criteria...