A5034817114- Assisted Reproductive Technology and Twin Pregnancy
- Prenatal Screening and Diagnostics
- Pregnancy and preeclampsia studies
- Cancer Risks and Factors
- Breast Cancer Treatment Studies
- Birth, Development, and Health
- Estrogen and related hormone effects
- Computational Drug Discovery Methods
- Reproductive Health and Technologies
- Global Cancer Incidence and Screening
- Glutathione Transferases and Polymorphisms
- Reproductive Biology and Fertility
- Neonatal Respiratory Health Research
- Nutrition, Genetics, and Disease
- Breast Lesions and Carcinomas
- Cancer Genomics and Diagnostics
- Bioinformatics and Genomic Networks
- BRCA gene mutations in cancer
- HER2/EGFR in Cancer Research
- Ovarian function and disorders
- Gene expression and cancer classification
- Genetic Syndromes and Imprinting
- Congenital Heart Disease Studies
- Ectopic Pregnancy Diagnosis and Management
- Ovarian cancer diagnosis and treatment
Norwegian University of Science and Technology
2016-2025
UNSW Sydney
2023-2024
Central Norway Regional Health Authority
2015-2018
Norwegian Institute of Public Health
2012
Akershus University Hospital
2012
University of Oslo
2012
Statistics Norway
1997
Molecular subtyping of breast cancer may provide additional prognostic information regarding patient outcome. However, its clinical significance remains to be established. In this study, the main aims were discover whether reclassification into molecular subtypes provides more precise outcome compared conventional histopathological grading and study cancer-specific survival in different subtypes. Cases occurring a cohort women born between 1886 1928 with long-term follow-up included study....
Is the risk of hypertensive disorders in pregnancies conceived following specific assisted reproductive technology (ART) procedures different from spontaneously (SC) pregnancies? ART had a higher disorders, particular cryopreservation, with highest seen twin frozen–thawed cycles. The is than SC pregnancies. increased may be partly explained by multiple and underlying infertility, but contribution has not been excluded. Population-based cohort study, including sibling design nationwide data...
Background A higher risk of placenta previa after assisted reproductive technology (ART) is well established. The underlying mechanisms are poorly understood, but may relate to embryo culture duration, cryopreservation, and cause infertility. Within-mother analyses, where each woman her own control (i.e., sibling design), help disentangle treatment contributions from maternal confounders that stable between pregnancies. We aimed investigate the in pregnancies achieved ART according...
Adverse long-term outcomes in individuals born before full gestation are not confined to at extreme gestational ages. Little is known regarding mortality patterns among the weeks close ideal gestation, and exact causes well understood; both of these crucial for public health, with potential modification risk.To examine risk all-cause noncommunicable diseases (NCD) deaths young adults preterm early term.This multinational population-based cohort study used nationwide birth cohorts from...
Preterm birth affects lungs in several ways but few studies have follow-up until adulthood. We investigated the association of entire spectrum gestational ages with specialist care episodes for obstructive airway disease (asthma and chronic pulmonary (COPD)) at age 18-50 years.
When do the differences in birth weights become apparent between singletons born after frozen embryo transfer (FET) and fresh (fresh ET)?Mean FET significantly higher starting from gestational week (GW) 33 among boys GW 34 girls.In recent years, there has been a steep rise recorded treatments, enabling widespread use of elective single transfer, thus reducing risks associated with multiple gestations. However, are heavier is risk large-for-gestational-age (LGA) (birth weight > 90...
The aim was to investigate whether children born after assisted reproduction technology (ART), particularly frozen-thawed embryo transfer (FET), are at higher risk of childhood cancer than fresh and spontaneous conception.We performed a registry-based cohort study using data from the 4 Nordic countries: Denmark, Finland, Norway, Sweden. included 7,944,248 children, out whom 171,774 were use ART (2.2%) 7,772,474 conception, representing all between years 1994 2014 in 1990 1984 2015 1985 Rates...
The use of assisted reproductive technologies (ARTs) is steadily increasing worldwide. outcomes associated with treatment for an individual's long-term health, including risk cardiovascular disease (CVD), remain largely unknown, due to the small number studies and their limited follow-up time.
Is transfer of vitrified blastocysts associated with higher perinatal and maternal risks compared slow-frozen cleavage stage embryos fresh blastocysts?Transfer is a risk preterm birth (PTB) when large baby, hypertensive disorders in pregnancy (HDPs) postpartum hemorrhage (PPH) but lower placenta previa blastocysts.Transfer frozen-thawed (FETs) plays central role modern fertility treatment, limiting the ovarian hyperstimulation syndrome multiple pregnancies. Following FET, several studies...
Are obstetric and perinatal outcomes in pregnancies after fresh blastocyst transfer (BT) comparable with those born cleavage stage (CT) spontaneous conception (SC)?Fresh BT is associated a higher risk of placental complications.BT optimizes the selection top-quality embryos increases pregnancy live birth rates per compared to CT. However, concerns have been raised as extended culture duration may increase complications impair outcomes. Previous studies shown preterm (PTB) among infants...
Introduction The complex etiology of autism spectrum disorder (ASD) is still unresolved. Preterm birth (<37 weeks gestation) and its complications are the leading cause death babies in world, those who survive often have long-term health problems. Length gestation, including preterm birth, has been linked to ASD risk, but robust estimates for whole range gestational ages (GAs) lacking. primary objective this study was provide a detailed description risk across entire GAs while adjusting sex...
Is the growth pattern of children conceived by ART different compared to naturally children.Both and underlying parental subfertility may contribute differences in early childhood between with without use ART.Children weigh less are shorter at time delivery. The extent which according mode conception persist during childhood, role subfertility, remains unclear.We conducted a prospective study population-based study. We studied 81 461 participating Norwegian Mother, Father Child Cohort Study...
Background Compared to naturally conceived children, adverse perinatal outcomes are more common among children born after assisted reproductive technology with fresh embryo transfer (fresh-ET) or frozen (frozen-ET). However, most previous studies could not adequately control for family confounding factors such as subfertility. We compared birth size and duration of pregnancy infants fresh-ET frozen-ET versus natural conception, using a within-sibship design account by maternal factors....
Background Some earlier studies have found indications of significant changes in cardiometabolic risk factors children born after assisted reproductive technology (ART). Most these are based on small cohorts with high selection bias. In this study, we compared the cardiovascular disease, obesity, and type 2 diabetes between singleton ART spontaneous conception (SC). Methods findings This was a large population-based cohort study individuals Norway, Sweden, Finland, Denmark 1984 2015. Data...
Frozen embryo transfer (frozen-ET) is increasingly common because of improved cryopreservation methods and elective freezing all embryos. Frozen-ET associated with higher risk hypertensive disorders in pregnancy than both natural conception fresh (fresh-ET), but whether this attributable to parental factors or treatment unknown.Using the Medical Birth Registries Denmark (1994-2014), Norway, Sweden (1988-2015), linked data from national quality registries databases on assisted reproduction,...
Background: Hospital regionalization involves balancing hospital volume and travel time. We investigated how time affect perinatal mortality the risk of delivery in transit using three different study designs. Methods: This nationwide cohort used data from Medical Birth Registry Norway (1999-2016) Statistics Norway. compared estimates across designs: (1) Observed confounder adjustment : Comparing women giving birth at hospitals sizes times (1,066,332 births), (2) Sibling comparison who moved...
The aim of this study was to compare breast cancer specific survival (BCSS) for invasive lobular carcinoma (ILC) and ductal (IDC) and, further, evaluate critically the prognostic value histopathological grading ILC examine E-cadherin as a marker in ILC.The comprised 116 611 carcinomas occurring between 1961 2008. All cases had been classified previously according type grade, stained oestrogen receptor (ER), progesterone (PR), antigen Ki67 (Ki67), epithelial growth factor (EGFR), cytokeratin...
ABSTRACT Objective The association of insomnia with subsequent breast cancer risk is largely unknown. Therefore, we assessed whether different symptoms and their combination are associated incident in a large population-based study. Methods In prospective cohort study, 33,332 women were followed to monitor the occurrence first invasive identified by Cancer Registry Norway. Insomnia including (1) nonrestorative sleep (2) difficulty initiating (3) maintaining self-reported using study specific...
Abstract STUDY QUESTION: Is the risk of imprinting disorders increased in children conceived after SUMMARY ANSWER: We found an adjusted odds ratio (AOR) 2.84 [95% CI: 1.34–6.01] for Beckwith–Wiedemann syndrome ART children, while Prader–Willi syndrome, Silver–Russell or Angelman was not ART. WHAT IS KNOWN ALREADY: Earlier studies, most them small, have suggested association between and disorders. DESIGN, SIZE, DURATION: This a binational register-based cohort study. All by Denmark (n = 45...
Pregnancy may reduce breast cancer risk through induction of persistent changes the mammary gland that make less susceptible to carcinogenic factors. It is not known what extent effects parity are independent other In a Norwegian cohort 58 191 women (2890 cancers), we assessed whether on postmenopausal be modified by menstrual and anthropometric We calculated attributable proportions due interaction as measure synergism. Parity, height, body mass index (BMI), age at menarche menopause were...