A5001859641- Congenital Heart Disease Studies
- Cardiac Structural Anomalies and Repair
- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Coronary Artery Anomalies
- Tracheal and airway disorders
- Streptococcal Infections and Treatments
- Aortic Disease and Treatment Approaches
- Chemical Synthesis and Reactions
- Asymmetric Synthesis and Catalysis
- Synthetic Organic Chemistry Methods
- Advanced Biosensing Techniques and Applications
- Glioma Diagnosis and Treatment
- Chemical Synthesis and Analysis
- Steroid Chemistry and Biochemistry
- Fluorine in Organic Chemistry
- Estrogen and related hormone effects
- Cancer Cells and Metastasis
- Cancer Genomics and Diagnostics
- Sulfur-Based Synthesis Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Cancer Treatment and Pharmacology
- Mechanical Circulatory Support Devices
- Cardiac Arrest and Resuscitation
- Congenital Diaphragmatic Hernia Studies
Princess Margaret Hospital for Children
2015-2025
Perth Children's Hospital
2019-2025
Jefferson University Hospitals
2024
Neurological Surgery
2024
Thomas Jefferson University Hospital
2024
Fiona Stanley Hospital
2016-2023
University of Miami
2022
The Royal Melbourne Hospital
2021
Gumma Paz College
2020
Children's Hospital at Westmead
2001-2019
In children undergoing heart surgery, nitric oxide administered into the gas flow of cardiopulmonary bypass oxygenator may reduce postoperative low cardiac output syndrome, leading to improved recovery and shorter duration respiratory support. It remains uncertain whether improves ventilator-free days (days alive free from mechanical ventilation).
Pulmonary atresia with intact ventricular septum is a rare congenital cardiac lesion significant anatomical heterogeneity. Surgical planning of borderline cases remains challenging and primarily based on echocardiography. The aim was to identify echocardiographic parameters that correlate surgical outcome develop discriminatory calculator. Retrospective review all pulmonary at statewide tertiary paediatric centre performed between 2004 2020. Demographic, clinical, data were collected....
Importance Children with congenital heart defects who undergo cardiopulmonary bypass (CPB) surgery are at risk for delayed or impaired neurodevelopmental outcomes. Nitric oxide (NO) added to the CPB oxygenator may reduce systemic inflammation due and improve recovery from surgery, including improved Objective To investigate neurodevelopment, health-related quality of life (HRQOL), factors associated neurodevelopment 12 months post in infants received NO standard CPB. Design, Setting,...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis of 25-hydroxy- and 1.alpha.,25-dihydroxy vitamin D3 from D2 (calciferol)David R. Andrews, Derek H. Barton, Robert Hesse, Maurice M. PechetCite this: J. Org. Chem. 1986, 51, 25, 4819–4828Publication Date (Print):December 1, 1986Publication History Published online1 May 2002Published inissue 1 December 1986https://pubs.acs.org/doi/10.1021/jo00375a013https://doi.org/10.1021/jo00375a013research-articleACS PublicationsRequest reuse...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAn oxyanionic [3,3]-sigmatropic approach to the ophiobolin ring systemLeo A. Paquette, John Colapret, and David R. AndrewsCite this: J. Org. Chem. 1985, 50, 2, 201–205Publication Date (Print):January 1, 1985Publication History Published online1 May 2002Published inissue 1 January 1985https://pubs.acs.org/doi/10.1021/jo00202a012https://doi.org/10.1021/jo00202a012research-articleACS PublicationsRequest reuse permissionsArticle...
Aryl imidazolylsulfonates participate as electrophilic coupling partners in palladium-mediated cross-coupling reactions. The aryl display good stability while maintaining reactivity a variety of palladium-catalyzed Imidazolylsulfonates are practical and economic alternative to triflates.
Abstract Das aus dem Säurechlorid erhaltene Keten (I) addiert Cyclopentadien (II) zu den isomeren Addukten (III) und (IV).
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTRapid and efficient construction of the ophiobolin nucleusLeo A. Paquette, David R. Andrews, James P. SpringerCite this: J. Org. Chem. 1983, 48, 7, 1147–1149Publication Date (Print):April 1, 1983Publication History Published online1 May 2002Published inissue 1 April 1983https://pubs.acs.org/doi/10.1021/jo00155a059https://doi.org/10.1021/jo00155a059research-articleACS PublicationsRequest reuse permissionsArticle Views394Altmetric-Citations48LEARN...
The mechanisms of attrition the Fontan population have been poorly characterised and it is unclear whether some deaths are potentially preventable. We analysed circumstances late death in patients with a circulation, special focus on identifying lesions amenable to intervention that may contributed decline their circulation.Between 1975 2018, total 105 from Bi-National Registry died beyond 1 year after completion, at median age 18.6 (IQR 13.8-26.0) years old, 12.7 6.0-19.3) completion.A...
Two examples of a practical enzymatic desymmetrization 2-substituted-1,3-propanediol and their application to the synthesis SCH51048, broad-spectrum orally active antifungal, are described. In each case, catalysis under both hydrolytic transesterification conditions is first example key intermediate, R,S-monoester triol 6, was obtained via Amano Lipase AK catalyzed hydrolysis dibutyrate 11b, or Novo SP435 acetylation 6. second example, diol 13a using 13c CE furnished S-monoester (S)-14b,c,...
The aim of this study was to compare the performance pulmonary homografts with stentless bioprosthetic valves [Medtronic Freestyle™ (Medtronic, Minneapolis, MN, USA)] in position patients congenital heart disease (CHD) younger than 20 years.
Previous studies investigating risk factors associated with reoperation or mortality after repair of complete atrioventricular septal defect (CAVSD) often have not included sizeable cohorts undergoing modified single-patch repair. Both double patch and techniques been widely used in Australia since the 1990s. Using a large multi-institutional cohort, we aimed to identify following CAVSD repair.Between January 1990 December 2015, total 829 patients underwent biventricular surgical at 4...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA direct, regio- and stereoselective 1.alpha.-hydroxylation of (5E)-calciferol derivativesDavid R. Andrews, Derek H. Barton, Kwok P. Cheng, Jean Pierre Finet, Robert Hesse, Graham Johnson, Maurice M. PechetCite this: J. Org. Chem. 1986, 51, 9, 1635–1637Publication Date (Print):May 1, 1986Publication History Published online1 May 2002Published inissue 1...
The Freestyle valve may be used for pulmonary replacement (PVR). Whether its stentless design and anticalcification treatment improve durability relative to alternative bioprostheses, however, is unknown long-term data are lacking.We performed a retrospective review of all PVRs by single surgeon in two institutions. All patients were contacted follow-up establish survival, New York Heart Association class reintervention. Up date, echocardiography was obtained assess function. Perioperative...