- Chemotherapy-induced cardiotoxicity and mitigation
- Cardiac Arrhythmias and Treatments
- Central Venous Catheters and Hemodialysis
- Chronic Lymphocytic Leukemia Research
- Lymphoma Diagnosis and Treatment
- Hematopoietic Stem Cell Transplantation
- Cancer Treatment and Pharmacology
- Infective Endocarditis Diagnosis and Management
- IgG4-Related and Inflammatory Diseases
- Healthcare Policy and Management
- Cardiac pacing and defibrillation studies
- Systemic Sclerosis and Related Diseases
- Atrial Fibrillation Management and Outcomes
- Trauma and Emergency Care Studies
- Takotsubo Cardiomyopathy and Associated Phenomena
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- PARP inhibition in cancer therapy
- Cardiac Imaging and Diagnostics
- Diabetes Treatment and Management
- Cardiac Arrest and Resuscitation
- Antimicrobial Resistance in Staphylococcus
- Platelet Disorders and Treatments
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Liver Diseases and Immunity
- Angiogenesis and VEGF in Cancer
Nazareth Hospital
2023-2024
University of South Florida
2016-2021
Florida College
2021
Moffitt Cancer Center
2016-2020
MedStar Washington Hospital Center
2011-2012
Fred Hutch Cancer Center
2000-2007
Tulane University
2007
Albany Medical Center Hospital
2007
Sapienza University of Rome
2000-2003
University of Washington
2003
Objectives There is little information about arrhythmia burden in cancer survivors with chemotherapy-induced cardiomyopathy (CIC). We hypothesise that the rates and risk of arrhythmias will be similar CIC when compared other non-ischaemic (NICMO) aetiologies. Methods retrospectively identified nine patients an implantable defibrillator 18 age sex-matched control (nine NICMO ischaemic (ICMO)). Rates odds were calculated by type cardiomyopathy, adjusting for days since cardioverter...
Background Ibrutinib is a tyrosine kinase inhibitor most commonly associated with atrial fibrillation. However, additional cardiotoxicities have been identified, including accelerated hypertension. The incidence and risk factors of new or worsening hypertension following ibrutinib treatment are not as well known. Methods We conducted retrospective study 144 patients diagnosed B cell malignancies treated (n=93) versus conventional chemoimmunotherapy (n=51) evaluated their effects on blood...
The aim of the study was to assess relationship between ischemic cerebrovascular accidents (ICVAs), that is, transient attack (TIA) or stroke, and left-sided heart valve abnormalities (LHVAs) in patients with systemic lupus erythematosus (SLE). In total, 71 consecutive SLE were studied. At baseline, history, clinical laboratory evaluations, as well trans-thoracic echocardiography (TTE) performed. From original population, so followed up for a mean time 5.80 +/- 1.53 years. After period 5.39...
Although ibrutinib-associated atrial and ventricular arrhythmias have been well described, there is little information about ibrutinib’s effects on other electrocardiographic parameters, particularly the QT interval. Using our database of 137 patients treated with ibrutinib, we retrospectively identified 21 in whom an electrocardiogram (ECG) was obtained both prior to after ibrutinib exposure. All traditional ECG parameters as dispersion were manually measured by electrophysiologist....
Carbonic anhydrase II (CAII) is expressed on alveolar epithelium and participates to CO2 elimination, fluid secretion post-capillary pH regulation. CAII overexpressed in animal models of lung fibrosis sites epithelial injury. Autoantibodies directed against (anti-CAII) have been described sera from patients affected by systemic sclerosis (SSc), but no study focused their clinical associations this disease. The aim was assess the presence anti-CAII SSc investigate association with...
Background Global budget payments (GBP) are considered effective in containing health care expenditures; however, information on their impact quality of cardiovascular is limited. We aimed to evaluate the effects GBP utilization, outcomes, and costs for 3 major conditions. Methods analyzed claims data hospital admissions Maryland from fiscal year 2013 2018. Using segmented regression, we evaluated temporal trends hospitalizations, length stay, percutaneous coronary intervention artery bypass...
The incremental value of stress myocardial perfusion SPECT (sMPI) in diagnosing obstructive CAD (CAD) may be affected by patient selection, since post-test probability is dependent on the conditional disease. As part a quality improvement project, we studied relationship between sMPI diagnostic accuracy and pretest at our institution. Patients who underwent CA within 90 days fiscal year 2021 were selected from hospital records. reports used to define test positivity. Abnormal was defined...
e19028 Background: Most of the information about ibrutinib-associated atrial fibrillation (AF) has been extrapolated from clinical trials for B cell lymphomas, however there is little AF and other supraventricular arrhythmias (SVT) in a “real-world” population patients (pts) receiving ibrutinib. Our study retrospectively evaluated patient characteristics risk factors by status cohort pts treated with ibrutinib, outside trial. Methods: We abstracted on 73 at Moffitt Cancer Center between...
Introduction: The overall survival of cardiac arrest patients is very poor. There a higher incidence on weekends especially Saturdays as per national statistics. Also, hospitals experience reduced staffing the weekends. We examined outcomes arrests compared to weekdays. Hypothesis: no difference in mortality which happen over weekday weekend. Methods: This retrospective cohort study used inpatient sample database identify from 2016 2019 presenting with weekdays vs SAS 9.3 was for data...