- Microbial Metabolic Engineering and Bioproduction
- Biofuel production and bioconversion
- Anaerobic Digestion and Biogas Production
- ATP Synthase and ATPases Research
- Algal biology and biofuel production
- biodegradable polymer synthesis and properties
- CO2 Reduction Techniques and Catalysts
- Environmental Toxicology and Ecotoxicology
- Metabolomics and Mass Spectrometry Studies
- Genomics and Phylogenetic Studies
- Carbon dioxide utilization in catalysis
- Computational Drug Discovery Methods
- Microbial Community Ecology and Physiology
- Plant nutrient uptake and metabolism
- Fish biology, ecology, and behavior
- Enzyme Production and Characterization
- Aquaculture Nutrition and Growth
- Photosynthetic Processes and Mechanisms
The University of Queensland
2017-2020
National Institute of Amazonian Research
2013
The global demand for affordable carbon has never been stronger, and there is an imperative in many industrial processes to use waste streams make products. Gas-fermenting acetogens offer a potential solution several commercial gas fermentation plants are currently under construction. As energy limits acetogen metabolism, supply of H2 should diminish substrate loss CO2 facilitate production reduced energy-intensive However, the effects on CO-grown have yet be experimentally quantified...
BRIEF RESEARCH REPORT article Front. Bioeng. Biotechnol., 27 March 2020 | https://doi.org/10.3389/fbioe.2020.00204
Living biological systems display a fascinating ability to self-organize their metabolism. This ultimately determines the metabolic robustness that is fundamental controlling cellular behavior. However, fluctuations in metabolism can affect homeostasis through transient oscillations. For example, yeast cultures exhibit rhythmic oscillatory behavior high cell-density continuous cultures. Oscillatory provides unique opportunity for quantitating of metabolism, as cells respond changes by...
Acetogens can fix carbon (CO or CO
This study aims to evaluate the transcriptome alterations, through cDNA libraries, associated with combined effects of two PAHs, benzo[a]pyrene (0.5 µg/L) and phenanthrene (50 µg/L), present in crude oil, on specimens Symphysodon aequifasciatus (discus fish) after 48 h exposure. The libraries were constructed according SOLiD™ SAGE™ protocol for sequencing SOLiD v.3 Plus sequencer. results analyzed by bioinformatics differentially expressed genes categorized using gene ontology program....
Abstract Acetogenic bacteria can convert waste gases into fuels and chemicals. Design of bioprocesses for carbon valorization requires quantification steady-state flows. Here, autotrophic chemostats containing Clostridium autoethanogenum grown on CO 2 H revealed that captured (460 ± 80 mmol/gDCW/day) had a significant distribution to ethanol (54 3 mol% with 2.4 0.3 g/L titer). We were impressed this initial result, but also observed limitations biomass concentration growth rate. Metabolic...
Abstract Acetogens can fix carbon (CO or CO 2 ) into acetyl-CoA via the Wood-Ljungdahl pathway (WLP) that also makes them attractive cell factories for production of fuels and chemicals from waste feedstocks. Although most biochemical details WLP are well understood systems-level characterisation acetogen metabolism has recently improved, key transcriptional features such as promoter motifs regulators still unknown in acetogens. Here, we use differential RNA-sequencing to identify a...