Renato de Souza Pinto Lemgruber

ORCID: 0000-0002-6616-0248
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About
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Research Areas
  • Microbial Metabolic Engineering and Bioproduction
  • Biofuel production and bioconversion
  • Anaerobic Digestion and Biogas Production
  • ATP Synthase and ATPases Research
  • Algal biology and biofuel production
  • biodegradable polymer synthesis and properties
  • CO2 Reduction Techniques and Catalysts
  • Environmental Toxicology and Ecotoxicology
  • Metabolomics and Mass Spectrometry Studies
  • Genomics and Phylogenetic Studies
  • Carbon dioxide utilization in catalysis
  • Computational Drug Discovery Methods
  • Microbial Community Ecology and Physiology
  • Plant nutrient uptake and metabolism
  • Fish biology, ecology, and behavior
  • Enzyme Production and Characterization
  • Aquaculture Nutrition and Growth
  • Photosynthetic Processes and Mechanisms

The University of Queensland
2017-2020

National Institute of Amazonian Research
2013

The global demand for affordable carbon has never been stronger, and there is an imperative in many industrial processes to use waste streams make products. Gas-fermenting acetogens offer a potential solution several commercial gas fermentation plants are currently under construction. As energy limits acetogen metabolism, supply of H2 should diminish substrate loss CO2 facilitate production reduced energy-intensive However, the effects on CO-grown have yet be experimentally quantified...

10.1186/s13068-018-1052-9 article EN cc-by Biotechnology for Biofuels 2018-03-01

BRIEF RESEARCH REPORT article Front. Bioeng. Biotechnol., 27 March 2020 | https://doi.org/10.3389/fbioe.2020.00204

10.3389/fbioe.2020.00204 article EN cc-by Frontiers in Bioengineering and Biotechnology 2020-03-27

Living biological systems display a fascinating ability to self-organize their metabolism. This ultimately determines the metabolic robustness that is fundamental controlling cellular behavior. However, fluctuations in metabolism can affect homeostasis through transient oscillations. For example, yeast cultures exhibit rhythmic oscillatory behavior high cell-density continuous cultures. Oscillatory provides unique opportunity for quantitating of metabolism, as cells respond changes by...

10.1073/pnas.1919531117 article EN cc-by-nc-nd Proceedings of the National Academy of Sciences 2020-05-29

This study aims to evaluate the transcriptome alterations, through cDNA libraries, associated with combined effects of two PAHs, benzo[a]pyrene (0.5 µg/L) and phenanthrene (50 µg/L), present in crude oil, on specimens Symphysodon aequifasciatus (discus fish) after 48 h exposure. The libraries were constructed according SOLiD™ SAGE™ protocol for sequencing SOLiD v.3 Plus sequencer. results analyzed by bioinformatics differentially expressed genes categorized using gene ontology program....

10.1371/journal.pone.0081083 article EN cc-by PLoS ONE 2013-12-03

Abstract Acetogenic bacteria can convert waste gases into fuels and chemicals. Design of bioprocesses for carbon valorization requires quantification steady-state flows. Here, autotrophic chemostats containing Clostridium autoethanogenum grown on CO 2 H revealed that captured (460 ± 80 mmol/gDCW/day) had a significant distribution to ethanol (54 3 mol% with 2.4 0.3 g/L titer). We were impressed this initial result, but also observed limitations biomass concentration growth rate. Metabolic...

10.1101/2020.01.23.917666 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2020-01-24

Abstract Acetogens can fix carbon (CO or CO 2 ) into acetyl-CoA via the Wood-Ljungdahl pathway (WLP) that also makes them attractive cell factories for production of fuels and chemicals from waste feedstocks. Although most biochemical details WLP are well understood systems-level characterisation acetogen metabolism has recently improved, key transcriptional features such as promoter motifs regulators still unknown in acetogens. Here, we use differential RNA-sequencing to identify a...

10.1101/668756 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2019-06-13
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