The present work is focused on the study of changes in microcirculation parameters patients who have undergone COVID-19 by means wearable laser Doppler flowmetry (LDF) devices. microcirculatory system known to play a key role pathogenesis COVID-19, and its disorders manifest themselves long after patient has recovered. In work, were studied dynamics one for 10 days before his disease 26 recovery, data from group undergoing rehabilitation compared with control group. A consisting several...

This article presents clinical results of wireless portable dynamic light scattering sensors that implement laser Doppler flowmetry signal processing. It has been verified the technology can detect microvascular changes associated with diabetes and ageing in volunteers. Studies were conducted primarily on wrist skin. Wavelet continuous spectrum calculation was used to analyse obtained time series blood perfusion recordings respect main physiological frequency ranges vasomotions. In patients...

ABSTRACT The work is devoted to the study of physiological variability microcirculatory‐tissue system (MTS) parameters under normal conditions and during functional tests. results were obtained in vivo using multimodal wearable analyzers implementing methods laser Doppler flowmetry fluorescence spectroscopy. Comprehensive data analysis calculation coefficients variation MTS human body for various topographic anatomical areas skin carried out. showed higher values coefficient area toes...

Introduction . This study aimed to assess blood microcirculation changes in the skin of forehead, cheeks and lower extremities before, during after performing a yoga inverted pose, using wearable laser Doppler flowmetry analyzers healthy volunteers. Materials methods The involved 25 volunteers, with an average age 37 [35–44] years. Blood were evaluated by six LAZMA PF wireless devices, placed pairs on supraorbital artery regions first toes feet, symmetrically right left. A three-phase...

ABSTRACT The paper is devoted to the study of perfusion and amplitude‐frequency spectra laser Doppler flowmetry (LDF) signals in patients with diabetes mellitus (DM) different skin areas upper lower extremities using a distributed system wearable LDF analysers. measurements were performed fingers, toes, wrists shins. mean values, amplitudes blood flow oscillations endothelial, neurogenic, myogenic, respiratory cardiac frequency ranges, values nutritive analysed. results revealed decrease...

In this study we demonstrate what kind of relative alterations can be expected in average perfusion and blood flow oscillations during postural changes being measured the skin limbs on brow forehead by wearable laser Doppler flowmetry (LDF) sensors. The aims were to evaluate dynamics cutaneous regulatory mechanisms microcirculation areas interest, possible significance those effects for diagnostics based monitoring. involved 10 conditionally healthy volunteers (44 ± 12 years). Wearable...

This work aims to study the functional state of resistive skin microvessels in patients with newly diagnosed arterial hypertension (AH), using portable laser Doppler flowmetry (LDF) devices. The included 89 men aged 30 60 years (44.4 ± 8.5) who had no known medical complaints, subjectively considered themselves healthy, and did not take medications on a regular basis. All underwent LDF left forearm, daily blood pressure (BP) monitoring (DBPM) arm, echocardiography, laboratory tests....

Introduction. Yoga breathing exercises make it possible to change the minute ventilation (MV) within a wide range, reaching states of hyper- and hypoventilation with corresponding shifts in gas exchange. In this work, interrelations between external respiration, parameters metabolism skin microcirculation were evaluated. Materials methods: 22 experienced volunteers performed yoga at frequency 3–3.5 times per 1–1.5 for 5 minutes, as well free 6 minutes before after exercises. Respiratory rate...

The growing interest in the development of new wearable electronic devices for mobile healthcare provides great opportunities methods assessing blood perfusion this direction.Laser Doppler flowmetry (LDF) is one promising methods.A fine analysis capillary flow structure and rhythm time frequency domains, coupled with a possibility round-the-clock monitoring can provide valuable diagnostic information about state microvascular flow.In study, implementation laser was utilised microcirculatory...

Introduction. Yoga breathing exercises improve the ability to significantly reduce respiratory rate. A decrease of minute respiration volume results in compensatory reactions microcirculatory bed caused by changes gas composition. The reaction regulatory mechanisms microvascular can be evaluated optical non-invasive laser Doppler flowmetry method. aim study was assess tissue microcirculation parameter people performing yoga exercises. Materials and methods. 25 volunteers performed at a...

A novel non-invasive, wearable VCSEL-based system for multipoint in − vivo measurements of blood perfusion was introduced. The operates on the basis laser Doppler flowmetry (LDF) method and allows microcirculation studies. sensors developed were used to analyse skin flow synchronization homologous regions contralateral limbs, both basal state during various functional tests. high synchronisation rhythms limbs healthy volunteers shown studies presented.

Laser Doppler flowmetry (LDF) was utilized to assess age-related changes in the blood microcirculation at skin sites with different morphology and regulation. The LDF signals obtained from glabrous of middle finger pad nonglabrous on dorsal wrist surface were analyzed. Statistically higher baseline perfusion observed zone older group volunteers compared younger participants. Observed site-specific differences can be used future experimental design for studies system patients pathologies.

Laser Doppler flowmetry (LDF) was used for detection of age-related changes in the blood microcirculation.The LDF signal simultaneously recorded from 3rd fingers' pads both hands.Amplitudes flow oscillations and wavelet coherence signals were data analysis.A statistical difference synchronisation myogenic found between two studied age groups.Myogenic perfusion younger group had a higher parameter than older group.Observed site-specific differences can be future design experimental studies...

The article is aimed at conducting pilot studies of microcirculation changes in patients with diabetes mellitus during the course intravenous infusions alpha lipoic acid. study was conducted passage a standard treatment. change parameters compared before start infusion course, and after course. A system wearable laser Doppler monitors used to conduct study. showed that although index does not undergo significant treatment process, spectral analysis recorded signal has potential...

The problem of diabetes mellitus (DM) has attracted scientists different specialities, as its prevalence is increasing worldwide and assumes the character a pandemic. use optical non-invasive diagnostic methods promising direction for early determination presence severity diabetic complications. This work aimed at assessing changes in uorescence intensity blood microcirculation level, evaluated skin patients with DM local cold heating tests. An experimental studies were carried out involving...

This work represents the first stage of a study microcirculation and oxidative metabolism parameters in skin women with type 1 diabetes mellitus early stages pregnancy. Laser Doppler flowmetry fluorescence spectroscopy were used to record diagnostic study. The main LDF recordings patients under (index upper lower extremities, normalised amplitudes blood flow oscillations), as well values when excited 365 nm light, measured presented.

Advances in the development of ultra-compact semiconductor lasers have opened up new possibilities for wearable devices implementing biophotonic technologies, such as laser Doppler flowmetry (LDF) and fluorescence spectroscopy (FS). This work is aimed to evaluate correlation between diagnostic parameters simultaneously registered by a newly developed device standard bedside fiber-based technique. Experimental studies with healthy volunteers using occlusion test showed high recorded two devices.

This paper presents the first results of study changes in microcirculatory-tissue systems functioning under spaceflight conditions.

This study is devoted to the trials of wearable diagnostic system that implements laser Doppler flowmetry technique analyse blood microcirculation. We do preliminary test with involvement limited group healthy volunteers different age and in patients type 2 diabetes. During series measurements, microcirculation parameters was measured for 10 minutes palmar surfaces big toes inner sides upper thirds shins. A statistically significant differences found bypass index, nutritive shunt ow shins...

The work is devoted to the study of effect complete hyper- and hypoventilation breathing on parameters blood flow microcirculation. Volunteers achieved hypo- hyperventilation modes by performing full breathing. correlations found between gas analysis microcirculation may indicate peculiarities mechanisms oxygen delivery biological tissues during changes in mode.