A5045199390- Pesticide Exposure and Toxicity
- Pesticide and Herbicide Environmental Studies
- Carcinogens and Genotoxicity Assessment
- Health, Environment, Cognitive Aging
- Insect and Pesticide Research
- Pesticide Residue Analysis and Safety
- Effects and risks of endocrine disrupting chemicals
- Immunotoxicology and immune responses
- Complementary and Alternative Medicine Studies
- Heavy Metal Exposure and Toxicity
- Environmental Toxicology and Ecotoxicology
- Aquaculture Nutrition and Growth
- Toxic Organic Pollutants Impact
- Environmental Justice and Health Disparities
- Animal testing and alternatives
- Agricultural safety and regulations
- Allergic Rhinitis and Sensitization
- Weed Control and Herbicide Applications
- Dermatology and Skin Diseases
- Public Health in Brazil
Lund University
2014-2021
Skåne University Hospital
2020
Getinge (Sweden)
2020
Universidad de Costa Rica
2014
Background: Mancozeb and its main metabolite ethylene thiourea (ETU) may alter thyroid function; hormones are essential for fetal brain development. In Costa Rica, mancozeb is aerially sprayed at large-scale banana plantations on a weekly basis.Objectives: Our goals were to evaluate urinary ETU concentrations in pregnant women living near plantations, compare their estimated daily intake (EDI) with established reference doses (RfDs), identify factors that predict concentrations.Methods: We...
Abstract Agricultural pesticides are extensively used for weed- and pest control, resulting in residues of these compounds food. The general population is mainly exposed through dietary intake. Exposure to certain has been associated with adverse human health outcomes. Our aim was assess urinary concentrations temporal trends the biomarkers commonly pesticides. Samples were collected from adolescents ( n = 1060) Scania, Sweden, 2000 2017. Concentrations 14 pesticide analyzed urine using...
Glyphosate (GLY), N-(phosphonomethyl) glycine, is the most widely used herbicide in world. It a broad-spectrum herbicide, also crop desiccation. Agricultural workers may be occupationally exposed and general populations to GLY mainly through diet. We studied kinetics of by measuring parent compound its metabolite aminomethylphosphonic acid (AMPA) urine samples three volunteers after an experimental oral exposure. further examined exposure AMPA spot 197 young adults population Scania,...
The filaggrin protein is important for skin barrier structure and function. Loss-of-function (null) mutations in the gene FLG may increase dermal absorption of chemicals.The objective study was to clarify if chemicals differs depending on genotype.We performed a quantitative real-time polymerase chain reaction (qPCR)-based genetic screen loss-of-function (FLG null) 432 volunteers from general population southern Sweden identified 28 null carriers. In exposure experiment, we exposed 23 31...
Thiabendazole (TBZ) is widely used as a pre-planting and post-harvest agricultural fungicide an anthelminthic in humans animals. TBZ of toxicological concern, since adverse effects including nephrogenic, hepatogenic, teratogenic neurological have been reported mammals. Occupational exposure can occur among workers the general public may be environmentally exposed to through diet. The metabolite 5-hydroxythiabendazole (5-OH-TBZ) was chosen biomarker LC/MS/MS method for quantification 5-OH-TBZ...
Pyrimethanil (PYM) is a fungicide used pre- and post-harvest on many crops. It has low acute toxicity but of toxicological concern because its antiandrogenic properties. The aim the current work was to investigate some metabolism estimate elimination kinetics PYM in humans after experimental oral dermal exposure. A liquid chromatography triple quadrupole mass spectrometry (LC–MS-MS) method developed validated for analysis metabolite 4-hydroxypyrimethanil (OH–PYM) human urine. applied analyze...
Imazalil (IMZ) is a fungicide used in the cultivation of vegetables, such as cucumbers, green houses or post-harvest on fruit to avoid spoilage due fungal growth. Agricultural workers can be occupationally exposed IMZ and general public indirectly by diet. The purpose this study was develop validate an LC–MS-MS method for analysis human urine. electrospray ionization selected reaction monitoring positive mode. Excellent linearity observed range 0.5–100 ng/mL. limit detection 0.2 ng/mL,...
Aerial Application of Mancozeb Is Associated with Elevated Urinary Ethylene Thiourea (ETU) Concentrations in Pregnant Women: the Infants' Environmental Health Study (ISA)Abstract Number:2682 Berna van Wendel de Joode*, Ana María Mora, Leonel Córdoba, Camilo Cano, Rosario Quesada, Moosa Faniband, Catharina Wesseling, Clemens Ruepert, Mattias Öberg, Brenda Eskenazi, Donna Mergler, Christian Lindh Joode* Universidad Nacional, Costa Rica, E-mail Address: [email protected] , Mora Córdoba Cano...
Background: Banana plantations are weekly sprayed with mancozeb and chlorpyrifos- treated bags being used continuously. Mancozeb its main metabolite ethylene thiourea (ETU) can alter thyroid hormone concentrations that key to fetal growth processes. With respect chlorpyrifos, prenatal exposures may impair growth. Methods: We measured, at different time points, creatinine-corrected ETU TCPy (chlorpyrifos' metabolite) in urine samples from pregnant women living less than five kilometers banana...