A5009901501- Airway Management and Intubation Techniques
- Anesthesia and Neurotoxicity Research
- Anesthesia and Pain Management
- Cardiac, Anesthesia and Surgical Outcomes
- Anesthesia and Sedative Agents
- Tracheal and airway disorders
- Veterinary Oncology Research
- Pediatric Pain Management Techniques
- Metabolism and Genetic Disorders
- Neurosurgical Procedures and Complications
- Central Venous Catheters and Hemodialysis
- Medical History and Innovations
- Vascular anomalies and interventions
- Hemodynamic Monitoring and Therapy
- Scoliosis diagnosis and treatment
- Congenital Heart Disease Studies
- Respiratory Support and Mechanisms
- Amino Acid Enzymes and Metabolism
- Pregnancy-related medical research
- Immunotherapy and Immune Responses
- Spine and Intervertebral Disc Pathology
- Neurogenetic and Muscular Disorders Research
- Foreign Body Medical Cases
- T-cell and B-cell Immunology
- Kidney Stones and Urolithiasis Treatments
Ibaraki Children's Hospital
1999-2024
SPring-8
2021-2023
Nihon Nohyaku (Japan)
2012-2022
The University of Tokyo
2022
Rothamsted Research
2017
University of Sheffield
2014
Veterinary Medical Center
2012
Rakuno Gakuen University
2010
Hitachi (Japan)
2009
Komatsu (Japan)
2008-2009
A new generation of more active succinate dehydrogenase (Sdh) inhibitors (SDHIs) is currently widely used to control Septoria leaf blotch in northwest Europe. Detailed studies were conducted on Zymoseptoria tritici field isolates with reduced sensitivity fluopyram and isofetamid; SDHIs which have only just or not been introduced for cereal disease control, respectively.
Both elicitor and suppressor of pisatin accumulation in pea leaves were found the pycnospore germination fluid Mycosphaerella pinodes, a pathogenic fungus plant. The was high, whereas low molecular weight substance. counteracted activity elicitor. Purification from fraction by gel filtration TLC gave two active components, F2 F5. These substances to be peptides because they showed positive color reaction with ninhydrin Lowry reagents. F5 inhibited induced inoculation non-pathogens, Erysiphe...
It is well known that tumor-infiltrating lymphocytes (TILs) and peripheral blood (PBLs) from patients with advanced-stage cancer have a poor immune response. Regulatory T cells (Tregs), characterized by the expression of cluster differentiation 4 intracellular FoxP3 markers, can inhibit antitumor immunoresponse. In present study, prevalence Tregs in tumor tissue dogs oral malignant melanoma was evaluated triple-color flow cytometry. The percentage malignancy significantly increased compared...
Background : This study compared the ease of insertion laryngeal mask airway (LMA™) with a partially inflated cuff using standard `nonrotational' technique versus rotational technique. Methods One hundred and forty‐five children undergoing anaesthesia LMA were randomly assigned to either method. The was in both groups. assessed by time taken complete insertion, number attempts before successful placement occurrence complications. Results success rate at first attempt higher group (99% 79%, P...
An oxalate-degrading bacterium in the gut microbiota absorbs food-derived oxalate to use this as a carbon and energy source, thereby reducing risk of kidney stone formation host animals. The bacterial transporter OxlT selectively uptakes from cells with strict discrimination other nutrient carboxylates. Here, we present crystal structures oxalate-bound ligand-free two distinct conformations, occluded outward-facing states. ligand-binding pocket contains basic residues that form salt bridges...
Taking advantage of the exposure dural sinuses during craniotomies, we measured confluens sinuum pressure by direct catheterization. The influence various surgical positions and other factors on was studied. When upper half body raised, decreased to reach zero at +25 degrees; when angle +90 degrees, a marked negative -12.7 +/- 3.0 cm H2O (mean SD) observed in adults. In children under 6 years age, however, such not even an degrees. 2.7 0.6 with patient reverse jackknife position (supine...
It is well known that lymphocytes from patients with advanced-stage cancer have impaired immune responsiveness and type1 T lymphocyte subsets in tumor bearing hosts are suppressed. Treg been reported to comprise a subgroup which inhibits cell mediated responses. In the present study, percentage of Treg, Th1 Tc1 peripheral blood dogs or without metastases was evaluated. The percentages metastatic were significantly less, greater, than those tumor. showed an inverse correlation dogs. concluded...
Summary We have used an intravenous micro‐drip infusion set to identify the epidural space in 350 infants and children. The was prepared with saline connected hub of needle. Free dripping regarded as a sign that needle tip had entered space. overall success rate this method 97.7%.
The cysteinyl residue at the active site of L-methionine gamma-lyase from Pseudomonas putida (MGL_Pp) is highly conserved among heterologous MGLs. To determine role Cys116, we constructed 19 variants C116X MGL_Pp by saturation mutagenesis. Cys116 mutants possessed little catalytic activity, while their affinity for each substrate was almost same as that wild type. Especially, C116S, C116A, and C116H composed function measured kinetic parameter k(cat) toward L-methionine. Furthermore,...
Recent data suggest a decreased prevalence of IFN-gamma-producing T lymphocytes (Type 1 cells) in tumor-bearing hosts. Moreover, it has been reported that Treg have strong impact on the activation and proliferation CD4 (+) CD8 lymphocytes; however, no previous reports described relationship between progression tumor, or Type cell populations dogs with malignant tumor. In this study, percentage Treg, Th1, Tc1 peripheral blood oral melanoma healthy was measured compared. Although percentages...
Abstract Morphological profiling is an omics-based approach for predicting intracellular targets of chemical compounds in which the dose-dependent morphological changes induced by compound are systematically compared to gene-deleted cells. In this study, we developed a reliable high-throughput (HT) platform yeast using drug-hypersensitive strains minimize use, HT microscopy speed up data generation and analysis, generalized linear model predict with high reliability. We first conducted...
We obtained venograms of the right internal jugular vein (RIJV) in 105 infants and children with congenital heart disease during cardiac catheterization. No major anomalies were found course RIJV. The diameter RIJV tended to increase patient's age, weight, height. However, some disproportionately small vessels seen 8% patients. depth from skin varied 2.5 20 mm did not significantly correlate or Confirmation by venography may facilitate clinical decisions be useful for performing percutaneous...
We obtained venograms of the right internal jugular vein (RIJV) in 105 infants and children with congenital heart disease during cardiac catheterization. No major anomalies were found course RIJV. The diameter RIJV tended to increase patient's age, weight, height. However, some disproportionately small vessels seen 8% patients. depth from skin varied 2.5 20 mm did not significantly correlate or Confirmation by venography may facilitate clinical decisions be useful for performing percutaneous...
Sacral intervertebral approach to the epidural space was introduced as an alternative caudal in infants and children 1987. We performed single-shot anaesthesia 200 with this using "drip tube" method for identification of space. Identification marked by commencement dripping chamber a micro-drip infusion set which connected needle. With i.v. extension tube, local anaesthetic solution injected "immobile needle" technique. Overall success rate block 96%. This is anatomically easy children,...
Transformation-defective (td) mutants with different sizes of genomic RNA were isolated from the Prague strain Rous sarcoma virus, subgroup C(PR-C). All six td viruses (tdTYPR-C) a single UV-irradiated stock PR-C (clone 2 TYPR-C) had slightly longer than did ordinary class b tdB77 and Rous-associated virus-7. spontaneously segregated in uncloned TYPR-C also contained size similar to tdTYPR-C RNA. On other hand, two another (LAPR-C) Fingerprint analysis confirmed that tdLAPR-C derived by...