A5013631117- Chronic Obstructive Pulmonary Disease (COPD) Research
- Medical Research and Treatments
- Asthma and respiratory diseases
- Ferroptosis and cancer prognosis
- Pharmacological Effects of Natural Compounds
- Traditional Chinese Medicine Studies
- Pancreatic function and diabetes
- Polysaccharides and Plant Cell Walls
- Pulmonary Hypertension Research and Treatments
- Cancer-related molecular mechanisms research
- Gynecological conditions and treatments
- Pediatric health and respiratory diseases
- Traditional Chinese Medicine Analysis
- RNA modifications and cancer
- Cancer-related gene regulation
- Lipid metabolism and disorders
- Autophagy in Disease and Therapy
- Acne and Rosacea Treatments and Effects
- Herbal Medicine Research Studies
- Salivary Gland Disorders and Functions
- Pelvic floor disorders treatments
- Healthcare and Venom Research
- Acupuncture Treatment Research Studies
- Flavonoids in Medical Research
- Hydrogen's biological and therapeutic effects
Chengdu University of Traditional Chinese Medicine
2012-2022
Jinan Military General Hospital
2009-2015
Dalian Medical University
2010
Second Affiliated Hospital of Dalian Medical University
2010
The aim of the present study was to determine whether liraglutide (LRG), a long acting glucagon-like peptide 1 analogue, exerted protective effect on free fatty acid (FFA)‑treated pancreatic β‑cells via activating autophagy. INS‑1 insulinoma islet cell lines were treated with FFA and levels necrosis, apoptosis autophagy detected using an MTT assay, flow cytometry electron microscopy (ECM). A type 2 diabetes mellitus mouse model established through treatment mice high‑fat diet for 8 weeks...
Lung adenocarcinoma (LUAD) is a common malignant tumor with poor prognosis. Recent studies have found that angiopoietin-like 4 (ANGPTL4) abnormally expressed in many tumors, so it can serve as potential prognostic marker and therapeutic target. However, its value LUAD remains unclear. We downloaded RNA sequence data for from The Cancer Genome Atlas (TCGA) database, methylation the University of California Santa Cruz genome clinical information. R software (version 4.1.1) was applied to...
1. UbcH10 is the cancer-related E2 ubiquitin-conjugating enzyme, and its overexpression has been demonstrated in a variety of malignancies. The aim present study to silence gene by RNA interference (RNAi) observe inhibitory effect on colorectal cancer cell growth vitro vivo. 2. We constructed expression vector pGPU6/GFP/Neo/UbcH10-RNAi (pUbcH10-RNAi), which contained short hairpin cassette. Then silencing lines LoVo/UbcH10-RNAi HT-29/UbcH10-RNAi were established. Reverse...
Abstract Introduction: People with refractory asthma (RA) often seek help from Chinese medicine due to dissatisfaction conventional treatments. External cold and internal fluid syndrome is the most common type of herbal formula Xiao-Qing-Long (XQL) decoction commonly prescribed for patients this syndrome. However, there no direct evidence support efficacy safety XQL RA treatment its potential mechanism still unclear. Methods: We propose a double-blind, placebo-controlled, randomized...
Background/Aim . Chronic obstructive pulmonary disease (COPD) is one of the most common health problems around world. Xiaoqinglong decoction (XQLD) has been clinically reported to improve lung function and shorten cough sputum in AECOPD patients, but its mechanism still unclear. This study aims investigate effects XQLD on inflammation apoptosis tissues explore underlying mechanisms acute exacerbation COPD (AECOPD) mice. Method Male C57BL/6J mice were used establish model by cigarette smoke...
Chronic obstructive pulmonary disease (COPD) is a multifactorial with gene-environment interaction leading to airflow limitation through the respiratory tract. Reports on association of matrix metalloproteinase 12 (MMP-12) polymorphisms COPD have been controversial. A new systematic evaluation which could examine whether MMP-12 mutations are associated susceptibility needed.We will search PubMed, EMBASE, Web Science, China National Knowledge Infrastructure and Google Scholar obtain eligible...
Abstract Background: Chronic obstructive pulmonary disease (COPD) is a major public health problem that severely affects the quality of life patients and may even endanger their lives. The key to prevent progression COPD active treatment during stable phase prevents reduces acute exacerbation COPD. Although modern medicine has achieved significant results in relieving clinical manifestations COPD, it difficult its entirely. As one classic aspects acupuncture moxibustion therapy, acupoint...