A5058624970- Esophageal Cancer Research and Treatment
- Gastric Cancer Management and Outcomes
- Esophageal and GI Pathology
- Lung Cancer Treatments and Mutations
- Cancer, Hypoxia, and Metabolism
- Cancer Research and Treatments
- Corneal surgery and disorders
- Lung Cancer Research Studies
- Autophagy in Disease and Therapy
- Pancreatic function and diabetes
- Neonatal Respiratory Health Research
- Corneal Surgery and Treatments
- RNA modifications and cancer
- Cellular Mechanics and Interactions
- Cancer-related Molecular Pathways
- Respiratory Support and Mechanisms
- Metastasis and carcinoma case studies
- Growth Hormone and Insulin-like Growth Factors
- Cancer-related molecular mechanisms research
- Intensive Care Unit Cognitive Disorders
- Sarcoma Diagnosis and Treatment
- Cancer Treatment and Pharmacology
- Reconstructive Surgery and Microvascular Techniques
- Heat shock proteins research
- Metabolism, Diabetes, and Cancer
Shanghai Jiao Tong University
2025
Zhejiang Cancer Hospital
2008-2024
Changzhi Medical College
2024
Chinese General Hospital College of Nursing and Liberal Arts
2024
Chinese People's Liberation Army
2024
Zhejiang University
2023
State Key Laboratory of Diagnosis and Treatment of Infectious Diseases
2021-2023
Second Affiliated Hospital of Xi'an Jiaotong University
2017-2023
Southern Medical University
2020-2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2023
The aim of the present study was to determine whether liraglutide (LRG), a long acting glucagon-like peptide 1 analogue, exerted protective effect on free fatty acid (FFA)‑treated pancreatic β‑cells via activating autophagy. INS‑1 insulinoma islet cell lines were treated with FFA and levels necrosis, apoptosis autophagy detected using an MTT assay, flow cytometry electron microscopy (ECM). A type 2 diabetes mellitus mouse model established through treatment mice high‑fat diet for 8 weeks...
Nomogram has demonstrated its capability in individualized estimates of survival diverse cancers. Here we retrospectively investigated 1195 patients with esophageal squamous-cell carcinoma (ESCC) who underwent radical esophagectomy at Zhejiang Cancer Hospital Hangzhou, China. We randomly assigned two-thirds the to a training cohort (n = 797) and one-third validation 398). Cox proportional hazards regression analyses were performed using cohort, nomogram was developed for predicting 3-year...
To observe the effect of early nutritional intervention on radiation-induced oral mucositis and status in patients with head neck cancer (HNC).A total 54 HNC were divided into (28 cases) late (26 groups. The group received enteral nutrition at beginning radiotherapy (RT), while after restricted feeding. Operators reported assessed timing extent during treatment. assessment indicators included body weight; mass index (BMI); Patient-Generated-Subjective Global Assessment (PG-SGA) score; levels...
Abstract Overexpressed matrix metalloproteinases, hypoxia microenvironment, and metabolic abnormality are important pathological signs of rheumatoid arthritis (RA). Designing a delivery carrier according to the characteristics RA that can control drug release in response disease severity may be promising treatment strategy. Psoralen is main active ingredient isolated from Psoralea corylifolia L. possesses excellent anti‐inflammatory activities as well improving bone homeostasis. However,...
The objective of this study was to investigate the prognostic and predictive significance tumor length in patients with esophageal squamous cell carcinoma undergoing radical resection.Tumor other clinicopathological variables were retrospectively evaluated 1435 treated resection between 2003 2010. Tumor analyzed as categorical continuous variable. Associations overall survival assessed Cox proportional hazards models. Model-based nomograms constructed. Predictive accuracy measured C-index....
e16116 Background: Neoajuvant chemoradiation is the standard treatment for resectable locally advanced esophageal squamous cell carcinoma (ESCC). Immune checkpoint inhibitors (ICIs) have shown a survival benefit ESCC and showed promising efficacy in neoadjuvant several cancers. This study aimed to evaluate safety of chemoradiotherapy (nCRT) combined with sequential tislelizumab followed by surgery ESCC. Methods: single-arm, phase Ib study. Eligibility criteria include histologically...
Background Preoperative fine-needle aspiration (FNA) is widely used to differentiate malignant from benign thyroid nodules, while intraoperative frozen sections (FS) are suggested as a systematic supplement for decision-making, but limitations still remain both procedures. Methods Medical records of 3807 patients with nodules who underwent pathological diagnoses (FS and FNA) at our hospital were reviewed. The diagnostic accuracy, sensitivity, specificity, positive predictive value (PPV),...
To describe a surgical technique for repair of an intractable sclerocorneal melt caused by serious chemical burn.This study includes description and review 3 representative cases.The combination tenonplasty with free oral buccal mucosa autograft was used in patients melts burns. Promising results were found each them. The area the healed successfully after surgery, integrities eyeballs salvaged.This provides new method burn.
Recurrent laryngeal nerve (RLN) lymph node metastasis used to be shown a predictor for poor prognosis in esophageal squamous cell carcinoma. The purpose of this study was evaluate the prognostic impact RLN and number metastatic nodes node-positive patients with carcinoma middle thoracic esophagus. A cohort 235 who underwent curative surgery esophagus investigated. evaluated by univariate multivariate analyses. Lymph found 133 patients. Among them, 81 had nodes, 52 at least one positive but...
The human leucine-rich repeats and immunoglobulin-like domains 2 (LRIG2) protein has been shown to be of prognostic value in several types cancer, however, the expression profiles LRIG2 have not described non-small cell lung cancer (NSCLC). present study evaluated mRNA tumor specimens obtained from 39 NSCLC patients by SYBR Green quantitative polymerase chain reaction formalin-fixed paraffin sections 116 immunohistochemistry. correlations between clinicopathological data were analyzed....