Monopolar electrocautery is usually a safe and effective technique used in laparoscopic cholecystectomy bile duct surgery, but it may lead to adverse consequences, even ventricular fibrillation (VF). Amiodarone an antiarrhythmic drug commonly practice treat atrial arrhythmias, induce tachyarrhythmia or VF. We report case of VF occurring twice during cholecystectomy. The first was caused by low-frequency leakage current the monopolar electrocautery. second due amiodarone causing further...

It has previously been reported that the influence of vitamin D on metabolism calcium and phosphorus is associated with diabetes, cardiovascular disease, Alzheimer's cancer other systemic diseases, considered an important indicator general health. The present study was conducted to determine effect various doses supplementation glucose metabolism, lipid concentrations, inflammation levels oxidative stress pregnant women gestational diabetes mellitus (GDM). randomized, double-blind...

A series of novel pyrazolyl acrylonitrile derivatives was designed, targeting Tetranychus cinnabarinus, and synthesized. Their structures were identified by combination 1H NMR, 13C MS spectra. The compounds 18 19 further confirmed X-ray diffraction. Extensive greenhouse bioassays indicated that compound exhibits excellent acaricidal activity against all developmental stages T. which is better than the commercialized cyenopyrafen spirodiclofen. It shown acute toxicity to mammals quite low....

Purpose: The purpose of this study was to explore if 16S rDNA amplicon sequencing can improve the conventional diagnosis causative pathogens for bacterial corneal infection. Methods: Corneal scraping and conjunctiva eyelid margin swab samples from infected eyes patients diagnosed with "bacterial infection" a random eye healthy participants were collected. Each used both aerobic anaerobic cultures sequencing. V3 V4 region amplified using polymerase chain reaction (PCR) sequenced on Illumina...

Background: Previous research has revealed that utilizing videos or images to educate primiparas about labor analgesia yields significantly superior results. WeChat supports various types of media, making it an ideal carrier for educational content. We have established a public account where content is presented through videos, images, and relevant scientific articles. will investigate the effectiveness platform in education. Methods: Primiparas were randomly assigned either education group...

ABSTRACT Severe fever with thrombocytopenia syndrome (SFTS) is an infectious disease caused by a novel bunyavirus that poses significant threat to human health. The aim of this study was identify precise and user‐friendly indicator for predicting the mortality patients SFTS. We retrospectively analyzed data from 181 hospitalized Inflammatory markers, including neutrophil‐to‐lymphocyte ratio (NLR), lymphocyte‐to‐monocyte (LMR), platelet‐to‐lymphocyte (PLR), systemic inflammation index (SII),...

Asthma is a complex inflammatory disease of the lungs marked by increased infiltration leukocytes into airways, which restricts respiratory function. Proliferator-activated receptor-γ coactivator-1 alpha (PGC-1α) has been recognized as an essential immunomodulator and potential novel anti-inflammatory target in asthma. The current study aims to investigate functions PGC-1α ovalbumin (OVA)-sensitized asthmatic mice underlying mechanisms. BALB/c mouse asthma model was induced OVA vivo....

The primary mechanism underlying pre-eclampsia (PE) remains one of the most burning problems in obstetrics and gynecology. In this study, we performed an expression profiling screen detected 1312 genes that were differentially expressed (p<0.05 fold change >1.5) PE placentas, including LEP SH3PXD2A. After validating microarray results, conducted quantitative methylation analysis SH3PXD2A preeclamptic (n = 16) versus normal placentas 16). Our results showed many CpG sites close to...

To evaluate the utility of glycated haemoglobin A1c (HbA1c) alone and in combination with haematocrit (HCT) for screening gestational diabetes mellitus (GDM) between 12-16 weeks.This prospective study was carried out Obstetrics Gynaecology Hospital Fudan University from November 2014 to February 2015. In total, 690 pregnant women 20 35 years old were included this study. All subjects received a routine blood examination HbA1c HCT at weeks (gw) 75-g oral glucose tolerance test 24-28 gw....

Sepsis-associated encephalopathy (SAE) is a diffuse brain dysfunction without overt central nervous system infection. Caffeine citrate has therapeutic effect on different diseases, while its role in SAE remains unclear. The expression levels of interleukin (IL)-18 and IL-1β were upregulated the cerebrospinal fluid subjects. In this study, rat model was established by cecal ligation puncture. inhibited SAE-induced neuronal apoptosis astrocytic activation, decreased reactive oxygen species...

Abstract Background The incidence rates of obesity and gestational diabetes mellitus (GDM) are increasing in parallel. This study aimed to evaluate the relationship between different indices, including prepregnancy body mass index (preBMI), first-trimester abdominal circumference (AC), circumference/height ratio (ACHtR), GDM, efficacy these three indices predicting GDM was assessed. Methods A total 15,472 pregnant women gave birth a singleton at Obstetrics Gynecology Hospital Fudan...

BACKGROUND:This study aimed to investigate the effects on gut microbiome of 40 infants delivered before term by cesarean section between antibiotic treatment and probiotics as assessed 16S rRNA quantitative polymerase chain reaction (qPCR) sequencing. MATERIAL AND METHODS:We divided premature into 4 groups according exposure antibiotics or probiotics: N group (No-probiotics No-antibiotics), A (antibiotics), P (probiotics), AP (antibiotics+probiotics). Fecal samples were collected days 1, 3,...

A broad spectrum of health benefits from intermittent fasting have been reported in studies on animal models and human subjects. However, the underlying mechanisms these beneficial effects remain largely elusive. The present study aimed to explore potential mode action mouse with a focus liver. C57BL/6 mice were subjected or <em>ad libitum</em> feeding as controls. It was determined that 12 h daily for 30 days significantly reduced cumulative food intake compared feeding. Fasting resulted...

To describe a surgical technique for repair of an intractable sclerocorneal melt caused by serious chemical burn.This study includes description and review 3 representative cases.The combination tenonplasty with free oral buccal mucosa autograft was used in patients melts burns. Promising results were found each them. The area the healed successfully after surgery, integrities eyeballs salvaged.This provides new method burn.

Purpose: To investigate the composition and diversity of microbiota on ocular surface patients with blepharitis in northwestern China via 16S rDNA amplicon sequencing. Methods: Thirty-seven divided into groups anterior, posterior mixed twenty healthy controls from were enrolled study. Samples collected eyelid margin conjunctival sac each participant. The V3-V4 region bacterial sample was amplified sequenced Illumina HiSeq 2500 sequencing platform, differences taxonomy among different...

There is growing interest regarding vitamin D and its potential role in gestational diabetes mellitus (GDM). We aimed to assess maternal status early pregnancy relationships with the risk of GDM a Chinese population Shanghai.The retrospective cohort study included total 7816 pregnant women who underwent 75-g oral glucose tolerance test (OGTT) during 24-28 weeks gestation. Participants' demographic information including age, prepregnancy body mass index (BMI), parity, season blood collection,...

ABSTRACT Objective This study aimed to identify candidate protein biomarkers from maternal serum for Down syndrome (DS) by integrated proteomic and bioinformatics analysis. Methods A pregnancy DS group of 18 women a control with the same number were prepared, proteins analyzed isobaric tags relative absolute quantitation mass spectrometry, differentially expressed (DS‐DEMSPs). Comprehensive analysis was then employed analyze DS‐DEMSPs both in this paper seven related publications. Results...

Objective To analyze pregnancy complications and outcomes of mothers with obesity or gestational diabetes mellitus (GDM). Methods 15065 were categorized into four three groups by pre-pregnancy body mass index (preBMI) abdominal circumference (AC), respectively, divided GDM non-GDM groups. Logistic regression analysis was utilized to identify independent factors associated outcomes. Results The overweight accounted for 16.0% 4.0% the total population, respectively. incidence rate 12.3%....

Background/Aims: Nonalcoholic steatohepatitis includes steatosis along with liver inflammation, hepatocyte injury and fibrosis. In this study, we investigated the protective role potential mechanisms of a traditional Chinese medicine ShenFu (SF) preparation in an vitro hepatic model. Methods: palmitic acid (PA)-induced murine AML12 cell injury, effects SF on cellular apoptosis intracellular triglyceride (iTG) level were assessed using TUNEL TG Colorimetric Assay. Reactive oxygen species...

To evaluate the effect of different bevacizumab concentrations on retinal neovascularization in a retinopathy prematurity (ROP) mouse model.