A5001239607- Antibiotic Use and Resistance
- Pharmaceutical Practices and Patient Outcomes
- Medication Adherence and Compliance
- HIV/AIDS Research and Interventions
- Oral and gingival health research
- Cancer Immunotherapy and Biomarkers
- Cutaneous Melanoma Detection and Management
- Plant-based Medicinal Research
- Pulmonary Hypertension Research and Treatments
- HIV, Drug Use, Sexual Risk
- Patient Satisfaction in Healthcare
- HIV/AIDS drug development and treatment
- Pharmacological Effects and Toxicity Studies
- Biosimilars and Bioanalytical Methods
- Immunodeficiency and Autoimmune Disorders
- Rheumatoid Arthritis Research and Therapies
- Heparin-Induced Thrombocytopenia and Thrombosis
- Epilepsy research and treatment
- Toxin Mechanisms and Immunotoxins
- Liver Disease Diagnosis and Treatment
- Pneumocystis jirovecii pneumonia detection and treatment
- Public Health in Brazil
- Cytokine Signaling Pathways and Interactions
- Hepatitis C virus research
- HIV/AIDS oral health manifestations
Hospital Clínico Universitario Virgen de la Victoria
2015-2023
Objective. To determine the effectiveness of a pharmaceutical intervention, based on CMO methodology (capacity, motivation and opportunity), to decrease prevalence PIMDINAC concept (potentially inappropriate medication+drug interactions+non-adherence concomitant medication) in people living with HIV infection. Material methods. Longitudinal prospective multicenter study, conducted between October 2021 2022. Patients older than 65 years, antiretroviral treatment drug prescription were...
Abstract Background Since the introduction of direct-acting antivirals, thousands chronic hepatitis C patients have been successfully treated. However, vulnerable populations a higher prevalence virus (HCV) infection and face barriers that impede their access to antivirals. We carried out an HCV microelimination program focused on population groups in Malaga. Methods People drug addiction treatment centers homeless shelters Malaga who participated between October 2020 2021 were included....
<h3>Background and importance</h3> Immune checkpoint inhibitors (ICIs) represent a milestone therapy in many types of cancer, such as melanoma. Nivolumab is programmed death receptor-1 (PD-1) blocking antibody with antitumour activity Only few studies have investigated the relationship between ICIs disorders coagulation–fibrinolysis system. <h3>Aim objectives</h3> To report case disseminated intravascular coagulation (DIC) metastatic melanoma patient treated nivolumab. A 50-year-old woman...
<h3>Background</h3> The use of biological drugs such as tocilizumab for rheumatoid arthritis (RA) is very expensive. However, some observational studies and recommendations from guidelines (BBF) suggest the possibility reducing dose biologicals to minimum effective in patients with good control disease. <h3>Purpose</h3> To assess financial impact, measured direct costs, reduced doses treatment RA a tertiary hospital. <h3>Material methods</h3> Observational, descriptive retrospective study...
<h3>Background</h3> Infection by <i>Pseudomonas aeruginosa</i> (PA) is a major cause of morbidity and mortality in hospitals, especially immunocompromised patients. Mortality from bacteraemia PA ranges 25% to 62%, depending on the study consulted. There are multiple factors associated with PA. <h3>Purpose</h3> Primary: determine at 90 days, positive blood culture, patients our centre. Secondary: risk mortality. <h3>Material methods</h3> Retrospective observational study. Includes culture for...
<h3>Background</h3> The management of infection by <i>Pseudomonas aeruginosa</i> (PA) is complicated. PA a microorganism with intrinsic resistance to many antibiotics, increasing agents that are currently considered therapeutic options. <h3>Purpose</h3> Analysing antimicrobial therapy prescribed for the treatment bacteremia at our centre. <h3>Material and methods</h3> Retrospective observational study conducted/completed from January 2011 December 2014. Inclusion criteria: patients positive...
<h3> Background</h3> Interleukin (IL)-6 is involved in the pathogenesis of rheumatoid arthritis (RA) via its broad effects on immune and inflammatory responses. Sustained IL-6 activity can cause tissue damage different tissues. Previous studies have shown that G allele at -174G >C (rs1800795) polymorphism related to high producing IL-6. <h3>Purpose</h3> The aim our study was explore potential role genetic polymorphisms as a predictor tocilizumab efficacy RA patients compare results with...
<h3>Background</h3> According to the World Health Organisation, selection of drugs is a participatory, ongoing and multidisciplinary process which should be based on efficiency, security, quality cost ensure rational use them. As result medicines, some tools have been developed in specialised areas that are essential. These called pharmacotherapeutics guides (PG) show political medicines medical environments, such as hospitals. The PG dynamic consensual reflection centre's...
<h3>Background</h3> Macitentan is a new endothelin receptor antagonist (ERA) which was compared with placebo in the SERAPHIN trial. The results showed no superior efficacy or safety (indirectly) other ERAs but better hepatic tolerance. <h3>Purpose</h3> To assess adaptation of pulmonary arterial hypertension (PAH) treatment prescriptions under our hospital protocol and its economic impact, to describe clinical using ERA, macitentan. <h3>Material methods</h3> A use for established September...
<h3>Background</h3> The World Health Organisation recognises the need to improve uptake and completion rates for postexposure prophylaxis (PEP). <h3>Purpose</h3> To analyse PEP dispensed by pharmacy service patients after an occupational (OE) or nonoccupational (NOE) exposure human immunodeficiency virus (HIV). compare usual clinical practice in our centre European acquired immune deficiency syndrome (AIDS) Clinical Society guidelines.<sup>1</sup> <h3>Material methods</h3> A descriptive,...
<h3>Background and importance</h3> The prescriptions of new antibiotics should be done with caution as improper use can lead to the emergence antimicrobial resistance. stewardship team (AST) commission infections (CI) have a fundamental task achieving adequate these drugs. It is important establish suitable circuit for control their prescriptions. Knowing how this operates essential if it necessary make any modifications. <h3>Aim objectives</h3> To analyse operation prescription/revision...