Blanca Luna Checa Fernández

ORCID: 0000-0002-6679-0987
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About
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Research Areas
  • Microfluidic and Bio-sensing Technologies
  • Characterization and Applications of Magnetic Nanoparticles
  • Magnetic Properties of Alloys
  • Nanoparticle-Based Drug Delivery
  • Metallurgical and Alloy Processes
  • Circadian rhythm and melatonin
  • Rare-earth and actinide compounds
  • Pleural and Pulmonary Diseases
  • Infectious Diseases and Tuberculosis
  • Powder Metallurgy Techniques and Materials
  • Water Quality Monitoring and Analysis
  • Stress Responses and Cortisol
  • Minerals Flotation and Separation Techniques
  • Innovative Microfluidic and Catalytic Techniques Innovation
  • Electrostatics and Colloid Interactions
  • Diagnosis and treatment of tuberculosis
  • Lignin and Wood Chemistry
  • Electrohydrodynamics and Fluid Dynamics
  • Hematological disorders and diagnostics
  • Ovarian function and disorders
  • Hypothalamic control of reproductive hormones
  • Neuroscience and Neuropharmacology Research
  • Sleep and Wakefulness Research
  • Nanoparticles: synthesis and applications
  • Iron oxide chemistry and applications

Universidad de Navarra
2007-2023

Universidad de Granada
1989-2021

Centro de Estudios e Investigaciones Técnicas de Gipuzkoa
2021

Institut de Physique de Nice
2018-2021

Université de Technologie de Compiègne
2017

Magnetic nanoparticles (MNPs) have been widely used to increase the efficacy of chemotherapeutics, largely through passive accumulation provided by enhanced permeability and retention effect. Their incorporation into biopolymer coatings enables preparation magnetic field-responsive, biocompatible that are well dispersed in aqueous media. Here we describe a synthetic route prepare functionalized, stable magnetite coated with temperature-responsive polymer, means hydrothermal method combined...

10.3390/polym10010010 article EN Polymers 2017-12-22

This series of two papers is devoted to the effect organic dye (methylene blue, MB; or methyl orange, MO) adsorption on surface either bare citrate-coated magnetic iron oxide nanoparticles (IONPs) their primary agglomeration (in absence an applied field) and secondary field-induced agglomeration. The present paper (Part I) focused physicochemical mechanisms adsorption-induced IONPs. Dye oppositely charged IONPs found be mostly promoted by electrostatic interactions very sensitive pH ionic...

10.1021/acsomega.1c02401 article EN cc-by-nc-nd ACS Omega 2021-07-19

In this work a combined, multifunctional platform, which was devised for the simultaneous application of magnetic hyperthermia and delivery antitumor drug gemcitabine, is described tested in vitro. The system consists magnetite particles embedded polymer envelope, designed to make them biocompatible, thanks presence poly (ethylene glycol) shell. commercial particles, after thorough cleaning, are provided with carboxyl terminal groups, so that at physiological pH they present negative surface...

10.3390/polym10030269 article EN Polymers 2018-03-06

In this work we report on the synthesis and characterization of magnetic nanoparticles two distinct origins, one inorganic (MNPs) other biomimetic (BMNPs), latter based a process bacterial synthesis. Each these kinds particles has its own advantages when used separately with biomedical purposes. Thus, BMNPs present an isoelectric point below neutrality (around pH 4.4), while MNPs show zero-zeta potential at 7, appear to be excellent agents for hyperthermia. This means that are better suited...

10.3390/pharmaceutics11060273 article EN cc-by Pharmaceutics 2019-06-11

In this paper, it is proposed that polymer-coated magnetic nanorods (MNRs) can be used with the advantage of a double objective: first, to serve as hyperthermia agents, and second, vehicles for antitumor drug doxorubicin (DOX). Two different synthetic methodologies (hydrothermal co-precipitation) were obtain MNRs maghemite magnetite. They coated poly(ethyleneimine) poly(sodium 4-styrenesulfonate), loaded DOX, using Layer-by-Layer technique. Evidence polymer coating loading was justified by...

10.3390/pharmaceutics11100517 article EN cc-by Pharmaceutics 2019-10-08

This paper (part II) is devoted to the effect of molecular adsorption on surface magnetic iron oxide nanoparticles (IONP) enhancement their (secondary) field-induced agglomeration and separation. Experimentally, we use Methylene Blue (MB) cationic dye citrate-coated maghemite provoke primary IONP in absence field. The secondary manifested through appearance needlelike micron-sized agglomerates presence an applied With increasing amount adsorbed MB molecules, size increases separation a...

10.1021/acs.langmuir.1c02021 article EN Langmuir 2021-08-26

The clinical manifestations of thoracic tuberculosis are highly varied and unspecific, can be superimposed on that any other bacterial infection affects the same organs.What is especially notable high frequency with which primary goes unnoticed persistence symptomology in secondary infection.This review analyses most common signs symptoms their presentation.Thoracic has a series patterns presentation cure that, although equally non-pathognomonic, occasion characteristic, discovery making...

10.4321/s1137-66272007000400004 article EN Anales del Sistema Sanitario de Navarra 2007-01-01

This work presents a detailed study of hydrogen decrepitation (HD) to obtain monocrystalline Nd-Fe-B powder. The effect temperature has been investigated optimize both particle size and shape. Differential scanning calorimetry was applied analyze the hydrogenation kinetics Nd2Fe14B Nd-rich phases in range 25 300ºC. Thermogravimetry X-ray diffraction allowed determining absorption whole alloy matrix phase, respectively. While electron microscopy (SEM) used visualize shape size, dynamic image...

10.2139/ssrn.4327813 article EN 2023-01-01

This work presents a detailed study of grain growth annealing gas-atomized Nd-Fe-B powders with different Nd contents, ranging from 27.5 to 31.5 wt.%. The influence Nb or Nb-Ga additions have also been investigated. First, the microstructure as-atomized was studied and initial size measured. Grain has carried out at 1150 ºC for 5 hours. addition resulted in decrease final due refining effect Nb-Fe rich compounds reduced amount free form liquid phase. Moreover, it determined by Thermo-Calc...

10.59499/ep235754756 article EN 2023-09-15
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