- Characterization and Applications of Magnetic Nanoparticles
- Nanoparticle-Based Drug Delivery
- Membrane-based Ion Separation Techniques
- Membrane Separation Technologies
- Microfluidic and Bio-sensing Technologies
- Vibration Control and Rheological Fluids
- Fuel Cells and Related Materials
- Electrostatics and Colloid Interactions
- Gold and Silver Nanoparticles Synthesis and Applications
- Nanoplatforms for cancer theranostics
- Asphalt Pavement Performance Evaluation
- Infrastructure Maintenance and Monitoring
- Geomagnetism and Paleomagnetism Studies
- Smart Materials for Construction
- Surfactants and Colloidal Systems
- Railway Engineering and Dynamics
- Supercapacitor Materials and Fabrication
- Nanopore and Nanochannel Transport Studies
- Seismic Performance and Analysis
- Graphene and Nanomaterials Applications
- Proteins in Food Systems
- Minerals Flotation and Separation Techniques
- Advanced battery technologies research
- Solar-Powered Water Purification Methods
- Railway Systems and Energy Efficiency
Instituto de Investigación Biosanitaria de Granada
2022-2025
Universidad de Granada
2016-2025
Andalusian Health Service
2024
Maroc Numeric Cluster
2021
University College Cork
2020
University of Graz
2010-2014
During the last few years, there has been an extraordinary increase in publications describing manifold applications of monoolein, one most important lipids fields drug delivery, emulsion stabilization and protein crystallization. In this perspective we present a comprehensive review phase behavior 'magic lipid'. An account various mesophases formed presence water collection formulae for calculation their nano-structural parameters are provided. Effects chemical biological molecules...
We present herein a study on the adsorption of anionic (SDS), cationic (CTAB), and nonionic (C12E5) surfactants onto silica nanoparticles. The effects this are studied by means static structure factor, S(q), collective diffusion coefficient, Dc, obtained from small-angle X-ray scattering dynamic light measurements, respectively. effective charge particles was determined also classical electrophoresis electroacoustic sonic-amplitude measurements. surface tension sample investigated. Of...
Magnetic nanoparticles (MNPs) have been widely used to increase the efficacy of chemotherapeutics, largely through passive accumulation provided by enhanced permeability and retention effect. Their incorporation into biopolymer coatings enables preparation magnetic field-responsive, biocompatible that are well dispersed in aqueous media. Here we describe a synthetic route prepare functionalized, stable magnetite coated with temperature-responsive polymer, means hydrothermal method combined...
The use of magnetic nanoparticles in hyperthermia, that is, heating induced by alternating fields, is gaining interest as a non-invasive, free side effects technique can be considered co-adjuvant other cancer treatments. Having sufficient control on the field characteristics, within admissible limits, focus presently material. In present contribution, no attempt has been made using composition than superparamagnetic iron oxide (SPION), or applying surface functionalization, which opens wider...
Embedding sensors in rail pads allows for direct monitoring of train–track interaction, which is essential preventive maintenance and sustainable management railway infrastructure. Nonetheless, given the critical role that play enhancing track performance durability, it crucial to define optimal configuration sensorized (InterActive Pads) ensures both mechanical reliability functional accuracy. Also, before its widespread application, mandatory provide calibration modelling allow...
Polyelectrolyte-coated carbon films are used as electrodes for energy extraction from salinity exchange.
Biomimetic magnetic nanoparticles mediated by magnetosome proteins (BMNPs) are potential innovative tools for cancer therapy since, besides being multifunctional platforms, they can be manipulated an external gradient field (GMF) and/or alternating (AMF), mediating targeting and hyperthermia, respectively. We evaluated the cytocompatibility/cytotoxicity of BMNPs Doxorubicin (DOXO)-BMNPs in presence/absence GMF 4T1 MCF-7 cells as well their cellular uptake. analyzed biocompatibility vivo...
Antitumor hyperthermia therapy is an emerging approach for the thermal treatment of cancer. Magnetite-based nanoparticles are very promising agents due to its biocompatibility and versatile application. In this study, engineered citrate functionalized magnetite resulted in adequate colloid desire application: 12.57 nm ± 3.86, −44.5 0.6 mV, hydrophilic character, 85.2 1.6 emu/g. Those citrate-functionalized colloids were embedded into a chitosan nanomatrix obtain cluster/shell...
This study investigates porous activated carbon (AC) particles as drug delivery vehicles for methotrexate (MTX). To enhance functionality, magnetic nanoparticles are embedded in AC imparting superparamagnetic properties (MAC composites), making...
The development of cost-effective and reliable railway monitoring technologies is crucial for the maintenance modern infrastructure. Embedding sensors into rail pads has emerged as a promising approach wheel–track interactions, but successful implementation these systems requires robust framework signal data acquisition analysis. This study validates custom-designed External Signal Acquisition Device (ESAD) use with smart pads, comparing its performance against high-precision commercial...
All efforts to obtain, reuse or purify water are extremely significant for society. Recently, researchers have begun delve in an idea born decades ago: the desalination of using highly porous electrodes. It is based on a fundamental aspect electrical double layers, namely, their huge capacitance. The ions solution can be partially removed under application electric field when fills space between electrodes, either bare (CDI, capacitive deionization), coated with ionic exchange membranes...
Conventional chemotherapy against colorectal cancer (CRC), the third most common in world, includes oxaliplatin (Oxa) which induces serious unwanted side effects that limit efficiency of treatment. Therefore, alternative therapeutic approaches are urgently required. In this work, biomimetic magnetic nanoparticles (BMNPs) mediated by MamC were coupled to Oxa evaluate potential Oxa-BMNP nanoassembly for directed local delivery drug as a proof concept future development targeted CRC....
In recent years, the capacitance of interface between charged electrodes and ionic solutions (the electric double layer) has been investigated as a source clean energy. Charge is placed on either by means ion-exchange membranes or an external power source. latter method, net energy produced simple solution exchange in open circuit, due to associated decrease layer. this work, we consider change with temperature variations: former decreases when raised, and, hence, cycle possible which some...
In this work a combined, multifunctional platform, which was devised for the simultaneous application of magnetic hyperthermia and delivery antitumor drug gemcitabine, is described tested in vitro. The system consists magnetite particles embedded polymer envelope, designed to make them biocompatible, thanks presence poly (ethylene glycol) shell. commercial particles, after thorough cleaning, are provided with carboxyl terminal groups, so that at physiological pH they present negative surface...
In this work we report on the synthesis and characterization of magnetic nanoparticles two distinct origins, one inorganic (MNPs) other biomimetic (BMNPs), latter based a process bacterial synthesis. Each these kinds particles has its own advantages when used separately with biomedical purposes. Thus, BMNPs present an isoelectric point below neutrality (around pH 4.4), while MNPs show zero-zeta potential at 7, appear to be excellent agents for hyperthermia. This means that are better suited...
To date, the need for biomaterials capable of improving treatment chronic skin wounds remains a clinical challenge. The aim present work is to formulate and characterize chitosan (Cs)/hydrolyzed collagen (HC) films as potential with improved mechanical hydration performances compared single component formulations. Films were made by solvent casting method, or without glycerin and/or PEG1500 plasticizers, resulting in total eight All characterized their physico-chemical characteristics...
In this paper, it is proposed that polymer-coated magnetic nanorods (MNRs) can be used with the advantage of a double objective: first, to serve as hyperthermia agents, and second, vehicles for antitumor drug doxorubicin (DOX). Two different synthetic methodologies (hydrothermal co-precipitation) were obtain MNRs maghemite magnetite. They coated poly(ethyleneimine) poly(sodium 4-styrenesulfonate), loaded DOX, using Layer-by-Layer technique. Evidence polymer coating loading was justified by...