- Enzyme Production and Characterization
- Biofuel production and bioconversion
- Polysaccharides and Plant Cell Walls
- Microbial Metabolites in Food Biotechnology
- Enzyme Catalysis and Immobilization
- Environmental Toxicology and Ecotoxicology
- SARS-CoV-2 and COVID-19 Research
- African Botany and Ecology Studies
- Liver Disease Diagnosis and Treatment
- Glycosylation and Glycoproteins Research
- RNA and protein synthesis mechanisms
- Gout, Hyperuricemia, Uric Acid
- Enzyme Structure and Function
- Phytochemicals and Antioxidant Activities
- Heavy metals in environment
- CRISPR and Genetic Engineering
- Viral Infections and Immunology Research
- Phytochemical and Pharmacological Studies
- Food composition and properties
- Microbial Metabolic Engineering and Bioproduction
- Toxic Organic Pollutants Impact
- Polysaccharides Composition and Applications
- Ethnobotanical and Medicinal Plants Studies
- DNA Repair Mechanisms
- Catalysis for Biomass Conversion
National Institutes of Health
2008-2025
National Institute of Environmental Health Sciences
2022-2025
Ministry of Earth Sciences
2018-2025
Government of India
2019-2023
Indian Institute of Technology Guwahati
2016-2023
California Institute of Technology
2023
Bioengineering Center
2022
Russian Academy of Sciences
2022
Indian Institute of Technology Gandhinagar
2020-2021
University of Rajasthan
2007-2014
Over the past two decades, birchwood and beechwood xylans have been used as a popular substrate for characterization of xylanases. Recently, major companies discontinued their commercial production. Therefore, there is need to find an alternative these substrates. Xylan extraction from Acacia sawdust resulted in 23.5% (w/w) yield. The extracted xylan composed xylose glucuronic acid residues molar ratio 6:1 with molecular mass ∼70 kDa. specific optical rotation analysis displayed that it...
The dynamic coastal and marine waters are frequently polluted by metals that affect the biota. Metal concentrations in biota, water sediments of Ennore estuary were monitored spatially over two years to understand their potential impact ecological risk. Variations chromium (Cr), copper (Cu), cadmium (Cd), lead (Pb) nickel (Ni) observed water, sediment organisms. metal (μg/l) order Ni (35) > Pb(16.9) Cu(15.8) Cr(12.5) Cd(5.6) (μg/g) was Cr(390) Pb(266) Cu(162) Ni(125) Cd(7.6). Elevated levels...
During the COVID-19 pandemic, people across globe turned to traditional and ethnobotanical remedies boost immunity, alleviate symptoms, prevent infections. Plants have long been a vital source of medicine, many common herbs plants possess antimicrobial, antiviral, immunomodulatory properties. This paper delves into botanical names, useful parts, family medicinal uses various such as Zingiber (Ginger), Capsicum, Azadirachta (Neem), Aloe, others, in relation prevention protection. The examined...
Cobalt and selenium are emerging concerns for marine organisms due to their raising levels in ambient environment toxicity. Bioassay tests were conducted on plankton evaluation assessment of cobalt Considering the ecological importance, diatoms such as Odontella mobiliensis, Coscinodiscus centralis, Skeletonema costatum copepod Longipedia weberi, mysid shrimp selected toxicity evaluation. The 96-h IC50 1.08 ± 0.04 mg/l diatom O. mobiliensis 3.52 0.02 C. 4.0 0.42 mg/l, 3.56 0.22 derived LC50...
Neutralizing antibodies targeting the SARS-CoV-2 spike protein have shown a great preventative/therapeutic potential. Here, we report rapid and efficient strategy for development design of neutralizing humanized nanobody constructs with sub-nanomolar affinities nanomolar potencies. CryoEM-based structural analysis nanobodies in complex revealed two distinct binding modes. The most potent nanobody, RBD-1-2G(NCATS-BL8125), tolerates N501Y RBD mutation remains capable B.1.1.7 (Alpha) variant....
This study compares different types of pretreatment methods, such as thermal at 120 °C, autoclaving, microwaving and ultrasonication in the presence water, dilute acid (1% H2SO4) or alkali NaOH) on Sorghum stalk with respect to holocellulose Acid Detergent/Insoluble Lignin content. Among all 1% NaOH along autoclaving 121 °C 15 psi for 30 min was most effective method stalk. Fourier Transform Infra-Red spectroscopy analysis this pretreated biomass showed removal lignin Field Emission Scanning...
The present study evaluates the possible radioprotective effect of Grewia asiatica fruit (rich in anthocyanin, carotenes, vitamin C, etc.) pulp extract (GAE) on cerebrum Swiss albino mice exposed to 5 Gy gamma radiation. For this, healthy from an inbred colony were divided into four groups: (1) Control (vehicle treated) (2) GAE treated - this group orally supplemented with (700 m/kg. b.w./day) once daily for fifteen consecutive days, (3) Vehicle irradiated mice, and (4) + Irradiated Mice...
The increasing use of nuclear radiation for human welfare necessitates the search new, safe, and cost-effective radioprotectors not only personnel charged with responsibility testing or working in laboratories, but also general public. With this view, present study has been undertaken to find out possible radioprotective potential Grewia asiatica fruit pulp extract (GAE). It is reported have a high content antioxidants such as vitamin C, anthocyanin, folate carotenoids, etc. that may play...